Clinical trials: Risk Factors Cardiovascular Disease
Morbid Obesity
Bariatric Surgery and HDL-cholesterol
Objective: to assess the effect of gastric bypass on HDL-cholesterol concentration and its Apolipoprotein A4 content at 1 year following bariatric surgery in comparison with a hypocaloric diet.
- Trial name
- NCT01707771
- Testing
- Roux-en-Y gastric bypass, diet and lifestyle modifications
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Cardiovascular Diseases, Heart Diseases
Pediatric Epidemiology of Cardiovascular Disease Risk Factors (Project Heartbeat)
To conduct a longitudinal, natural history study of cardiovascular disease risk factors in children. Growth curves were compared for levels of blood pressure, lipids, cardiac structures and function, and related to physical…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis
- Trial name
- NCT00005264
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Cardiovascular Risk Factor
The Healthy Cantonese Diet on Cardiometabolic Syndrome
The DASH diet (Dietary Approaches to Stop Hypertension) have been proven to lower risk of cardiovascular diseases. But the DASH diet is inconsistent with Chinese dietary pattern.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, High Blood Pressure, Hypertension
- Trial name
- NCT04064281
- Testing
- the healthy Cantonese diet, the typical Cantonese diet
- Volunteers
- 90 people
- Sponsor
- Sun Yat-sen University
Risk Factors
Establishment of Risk Factors Model of Drug-induced Coagulation Disorder Caused by Cefoperazone Sulbactam Sodium
The incidence rate of drug-induced blood diseases accounts for about 10% of all drug-induced diseases, most of which are serious at the time of onset, and the mortality rate can be as high as 32.5%.
- Trial name
- NCT05535309
- Testing
- cefoperazone sulbactam sodium
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Qianfoshan Hospital
Hypertension, Diabetes
A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti
Investigators will establish a longitudinal cohort of ~3,000 adults >18 years in Port-au-Prince using multistage random sampling, and follow them longitudinally to evaluate the prevalence and incidence of cardiovascular disease…
- Conditions
- Hypertension, Diabetes, Obesity, Kidney Diseases
- Trial name
- NCT03892265
- Testing
- Observational Study
- Where
- Haiti
- Volunteers
- 3,005 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes Mellitus, Hypertension
Efficacy of Exercise at a Fitness Club for Cardiovascular Risk Reduction
The purpose of the study is to determine whether exercise has further beneficial effects on improving cardiovascular risk factors such as hypertension, high cholesterol level or diabetes mellitus, when added to the standard…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- NCT00106236
- Testing
- exercise
- Where
- Japan
- Volunteers
- 561 people
- Sponsor
- Sapporo Health Promotion Foundation
Transcatheter Aortic Valve Replacement, Coronary Artery Disease
Coronary Artery Disease Assessment Strategies in TAVI Patients
Coronary artery disease (CAD) and aortic stenosis frequently coincide. Before valve intervention, invasive coronary angiography is routinely performed to assess coronary status.
- Conditions
- Transcatheter Aortic Valve Replacement, Coronary Artery Disease, Heart Disease Risk Factors
- Trial name
- CAT (NCT06559332)
- Testing
- Risk-based CAD management, Invasive coronary angiography
- Where
- Switzerland
- Volunteers
- 546 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Risk Factor, Cardiovascular Diseases
The DEtermining Statin Intolerance FOr Rosuvastatin (DESIFOR) Trial
This study will enroll patients who previously were not able to tolerate being on a statin medication due to muscle-related side effects.
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Adverse Effect
- Trial name
- DESIFOR (NCT03889314)
- Testing
- Rosuvastatin 20mg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Stroke
Effects of Intravenous Laser Irradiation of Blood Treatment With Different Colored Lights on Controlling Recurrent Stroke Risk Factors and Neurological Function in Stroke Patients
Introduction and Purpose: Patients with stroke have over a decade of experience with vascular laser treatment. Previous studies predominantly used low-energy vascular lasers with red light, specifically helium-neon lasers with a…
- Trial name
- NCT06232499
- Testing
- Intravenous Laser Irradiation of Blood
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Atherosclerosis, Myocardial Infarction
Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness
This minimal risk protocol is designed to assess the reproducibility of B-mode ultrasound measurements of carotid intima media thickness (IMT) when the scans are performed in CC Radiology and read using a computerized edge…
- Trial name
- NCT00001904
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sudden Cardiac Death, Cardiomyopathies
Sudden Cardiac Death - Screening Of Risk Factors
The investigators have created a way of quickly collecting information in a large scale young population regarding the presence of some severity indicators that may allow us to classify them into: seemingly "low risk" and…
- Conditions
- Sudden Cardiac Death, Cardiomyopathies, Channelopathies
- Trial name
- SCD-SOS (NCT01845909)
- Testing
- ECG and survey screening
- Where
- Portugal
- Volunteers
- 15,351 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Cardiovascular Disease, Diabetes
Effect of Vitamin D3 Supplementation on Cardiometabolic Risk
Supplementation studies with vitamin D have been performed where cardiometabolic risk markers have been assessed but these are few, and results are inconsistent. Hence, the purpose of this study is to determine: 1.
- Conditions
- Cardiovascular Disease, Diabetes, Bone Disease
- Trial name
- NCT02359214
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Chester
Hyperlipidemias, Overweight and Obesity
Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors
The purpose of this study is to conduct a preliminary test of the effectiveness of various educational interventions to promote adoption of a whole-food, plant-strong diet and reduce specific cardiovascular risk factors in…
- Conditions
- Hyperlipidemias, Overweight and Obesity, Diabetes
- Trial name
- NCT03330548
- Testing
- TeleMOVE!, Culinary Rx
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Phoenix VA Health Care System
Cancer, Anticancer Treatment
Risk Prediction Scores for Cardiotoxicity in Cancer Patients Treated With Cardiotoxic Anticancer Therapies in Europe
Cancer management has undergone major advances over the past 30 years. Several anticancer therapies are now highly effective, allowing many cancers to become chronic diseases through sequential lines of treatment.
- Conditions
- Cancer, Anticancer Treatment, Cardiovascular Disease Risk Factor, Cardiovascular Diseases
- Trial name
- EUCARTOXSCORES (NCT07621289)
- Testing
- antineoplastic agents, endocrine therapy, immunostimulants drugs (ATC classification)
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Caen
Insulin Resistance, Atherosclerosis
The Effect of Cranberry Extract Supplementation on Cardiovascular Risk Factors in Obese, Insulin Resistant Humans
The purpose of this study is to determine the health benefits of cranberry extract in people who are at risk for diabetes and heart problems.
- Trial name
- NCT02068144
- Testing
- Cranberry Extract
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hypertension, Obesity
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States.
- Conditions
- Hypertension, Obesity, Nutrition, Healthy
- Trial name
- FIM-BCS (NCT06504914)
- Testing
- Assigned Interventions
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Illinois Chicago
Obesity, Morbid Obesity
Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
The growing obesity pandemic has a major impact on global cardiovascular (CVD)-related morbidity and premature mortality, severely compromising the quality of life of those affected and significantly increasing costs for the…
- Trial name
- KETOHEART (NCT05781269)
- Testing
- VLCKD, r-MedDiet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Cardiovascular Risk Factor, Lipemia
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a…
- Trial name
- NCT03958734
- Testing
- High-fat meal
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Acute Coronary Syndrome, Contrast-Induced Acute Kidney Injury
Predictors of Contrast-induced Acute Renal Injury in Patients With Acute Coronary Syndrome
This observational study aims to identify predictors of contrast-induced acute kidney injury (CI-AKI) in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
- Trial name
- PC-AKI-ACS (NCT07294911)
- Testing
- Observational data collection
- Where
- Kazakhstan
- Volunteers
- 88 people
- Sponsor
- Karaganda Medical University
Diabetes Mellitus, High Blood Pressure
Comparative Effectiveness of Family vs. Individually Focused Diabetes Education and Support
The objective of this study is to compare the effectiveness of a novel program-Family Support for Health Action (FAM-ACT) - to individual patient-focused diabetes self-management education and support (I-DSMES).
- Conditions
- Diabetes Mellitus, High Blood Pressure, High Blood Sugar, Hypertension
- Trial name
- NCT03812614
- Testing
- FAM ACT, I-DSMES
- Where
- 2 sites in United States
- Volunteers
- 444 people
- Sponsor
- University of Pittsburgh
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