Clinical trials: Risk Factors Cardiovascular Disease
Dementia, Mild Cognitive Impairment
Norwegian COgnitive Impairment After STroke (NorCOAST) Study
A prospective observational multicenter study aiming to describe incidence, and identify predictors for development of poststroke dementia (PSD) and mild cognitive impairment (MCI) after stroke
- Conditions
- Dementia, Mild Cognitive Impairment, Stroke
- Trial name
- Nor-Coast (NCT02650531)
- Where
- Norway
- Volunteers
- 816 people
- Sponsor
- Norwegian University of Science and Technology
Type 2 Diabetes, Cardiovascular Diseases
The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Purpose To assess the impact of inclusion of 2 eggs daily for 6 weeks in an otherwise vegan diet compared to a vegan diet on cardio-metabolic risk and dietary pattern in adults at risk for type 2 diabetes.
- Trial name
- NCT04316429
- Testing
- Egg included vegan phase, Vegan Phase
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Griffin Hospital
Stroke
Vitamin D and Stroke
Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin…
- Trial name
- NCT02916030
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Metabolic Syndrome, Overweight and Obesity
Pediatric Metabolic Syndrome Study
The Pediatric Metabolic Syndrome Study is an observational study being conducted at the Medical University of South Carolina to investigate cardiometabolic risk parameters in obese subjects ages 4 to 21.
- Conditions
- Metabolic Syndrome, Overweight and Obesity, Cardiovascular Risk Factor
- Trial name
- PMSS (NCT03570840)
- Where
- United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cardiovascular Disease Risk, Rheumatoid Arthritis (RA)
Cardiovascular Disease Awareness in Rheumatoid Arthritis and Knee Osteoarthritis
Cardiovascular diseases (CVD) are still the most common cause of death. For these reasons, individuals, especially those with chronic diseases, need to be aware of CVD.
- Conditions
- Cardiovascular Disease Risk, Rheumatoid Arthritis (RA), Knee Osteoarthritis
- Trial name
- NCT07056608
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Peripheral Vascular Disease
Systematic Assessment of Vascular Risk
It is hypothesized that patients with vascular disease are undertreated for modifiable risk factors, leading to increased morbidity and mortality in this population.
- Trial name
- NCT00378040
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University Health Network, Toronto
Type 2 Diabetes, Cardiovascular Risk Factor
Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)
Diabetes is an independent risk factor for ischemic heart disease (CAD) and heart failure, and cardiovascular diseases are the main cause of mortality and morbidity in patients with diabetes.
- Trial name
- FIORE (NCT04183868)
- Testing
- Empagliflozin 10 MG, Glimepiride 2 mg
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Catanzaro
Stroke, Cognitive Impairment
Cognitive and Emotional Impairment After Stroke
Cognitive and emotional symptoms are often seen in the acute phase of a stroke. The prevalence of such symptoms later and the mechanisms explaining the symptoms are not fully known.
- Conditions
- Stroke, Cognitive Impairment, Vascular Dementia
- Trial name
- NCT00506818
- Testing
- Multifactorial vascular-risk-factor-intervention
- Where
- Norway
- Volunteers
- 250 people
- Sponsor
- Sykehuset Asker og Baerum
Myocardial Infarction, Acute Coronary Syndrome
Impact at One Year of a Secondary Prevention Educational Program on Cardiovascular Risk Factors
In secondary prevention, the beneficial role of cardiac rehabilitation programs after myocardial infarction, percutaneous coronary intervention or coronary artery bypass is now well established.
- Trial name
- OLIMPIC (NCT00758810)
- Where
- 4 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Diabetes, Cardiovascular Risk
The Effects of Soy Protein and Isoflavones on Glycemic Control, Insulin Sensitivity and Cardiovascular Risk Factors
The investigators propose to perform a double-blind, randomized placebo-controlled trial to examine the hypothesis that soy protein with isoflavones could improve glycemic control, insulin sensitivity and decrease cardiovascular…
- Trial name
- NCT00856882
- Testing
- soy protein, isoflavones, milk protein
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cardiovascular Diseases, Inflammation
Dietary Intake of Alpha-linolenic Acid in Elderly
The purpose of this study is to evaluate the antiatherogenic and anti-inflammatory potential of an adequate intake of alpha-linolenic acid in elderly.
- Conditions
- Cardiovascular Diseases, Inflammation, Metabolism Disorder, Lipid
- Trial name
- NCT03025620
- Testing
- Rapeseed oil, Sunflower oil
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiovascular Disease Prevention, Cardiometabolic Diseases
Preventative Screening and Health Coaching in a Food Insecure Population
The goal of this longitudinal study is to investigate the role of virtual health coaching on mitigation of cardiometabolic disease risk in an underserved, food insecure population.
- Conditions
- Cardiovascular Disease Prevention, Cardiometabolic Diseases, Cardiovascular Risk Factor, Cardiovascular Risk Score
- Trial name
- HEALTHCOACH (NCT06907524)
- Testing
- Longitudinal, Individualized Health Coaching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Overweight, Prediabetic State
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and…
- Conditions
- Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal
- Trial name
- ATTAIN-NOW (NCT07794579)
- Testing
- Orforglipron
- Where
- 180 sites in United States, Argentina and 10 more
- Volunteers
- 2,001 people
- Sponsor
- Eli Lilly and Company
Stroke
Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III
The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH). ICH, a type of bleeding into brain tissue, is a type of stroke that can result in death or disability in a…
- Trial name
- GERFHS-III (NCT00930280)
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Wearable Device, Cardiovascular Disease
HEARTS in Sync + CardioWatch 287-2
The goal of this interventional study is to evaluate the implementation, usability, and clinical outcomes of a wearable medical-grade device in a virtual Cardiac Rehabilitation (CR) program, titled HEARTS in Sync.
- Conditions
- Wearable Device, Cardiovascular Disease, ASCVD Management, CHF - Congestive Heart Failure
- Trial name
- NCT07322510
- Testing
- Remote Patient Monitoring with Corsano CardioWatch 287-2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Diabetic Retinopathy, Diabetic Macular Edema
Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images
The objective of this study is to compare the results of a deep learning approach to diabetic retinopathy assessment with results from (1) an in-person examination with an ophthalmologist, and (2) the assessments of optometrists…
- Trial name
- NCT03694145
- Testing
- In-Person Eye Examination
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Charles Drew University of Medicine and Science
Heart Failure
Heart Failure IDentification in a High Risk Cardiovascular OutpatiEnt Population (HIDE)
This is a pilot, multicenter, real-world, single-visit, low risk, phase IV interventional study to efficiently identify new cases of heart failure (HF) Stage C in subjects who are at risk of cardiovascular (CV) disease in…
- Trial name
- HIDE (NCT04143919)
- Testing
- NYHA assessment, Serum NT-proBNP concentration, Transthoracic Ecocardiogram
- Where
- 5 sites in Dominican Republic, El Salvador and 1 more
- Volunteers
- 317 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Kidney Diseases, Cardiovascular Risk Factors
Cardiovascular Risk Factors and Physical Activity in Chronic Kidney Patients on Peritoneal Dialysis
The objective of this study was to examine the association between cardiovascular risk factors and physical activity parameters in patients with chronic kidney disease who are treated with peritoneal dialysis.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Risk Factors, Arterial Stiffness, Physical Activity
- Trial name
- NCT07041554
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Dokuz Eylul University
Diabetes Mellitus, Type 2
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Aim: The United Kingdom Prospective Diabetes Study (UKPDS) showed a reduction in cardiovascular events in obese patients with type-2-diabetes treated with metformin compared with other hypoglycaemic treatments with no difference…
- Trial name
- NCT00118963
- Testing
- Metformin, Insulin BIAsp30 (Novolog 70/30), Repaglinide
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Steno Diabetes Center Copenhagen
Cardiovascular Diseases
Cardiovascular Disease Risk of Awareness
The Cardiovascular Risk Reduction Program (CARDIOREP) aims to raise risk awareness and reduce risk factors.
- Trial name
- NCT06000436
- Testing
- Cardiovascular disease risk assessment, Training and Consultancy, Mobile Application
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University