Clinical trials: Risk Factors Cardiovascular Disease
Obesity, Dysglycemia
Secular Trends in the Prevalence of Cardiometabolic Risk Factors Among Teenage School Children in Urban South India
The prevalence of cardiometabolic risk is high among South Asians which manifests itself at an early age. Studies have reported that unhealthy food choices, inadequate physical activity and lack of awareness on healthy lifestyle…
- Conditions
- Obesity, Dysglycemia, Dyslipidemias, Hypertension
- Trial name
- NCT04015726
- Where
- India
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Cardiovascular Diseases, Metabolic Syndrome
Effect of Dried Fruit on Cardiometabolic Risk Factors
This is a 2-period randomized crossover study with free-living subjects on self-selected diets. The objective of this study is to compare the effects of ¾ cup of a blend of dried plums, figs, dates and raisins (DPFDR) with an…
- Trial name
- NCT03020758
- Testing
- Dried Fruit, High Carbohydrate Snack
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Penn State University
COVID-19, Cardiovascular Diseases
Cannabidiol in Patients With COVID-19 and Cardiovascular Disease or Risk Factors
Non-critical patients, hospitalized within the previous 24 hours who tested positive for COVID-19 and have a prior history of cardiovascular disease (CVD) and/or significant risk factors for CVD will be treated for 28 days.
- Conditions
- COVID-19, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- NCT04615949
- Testing
- Cannabidiol, pharmaceutically produced with < 5 ppm THC
- Where
- 20 sites in United States, Brazil and 1 more
- Volunteers
- 90 people
- Sponsor
- Cardiol Therapeutics Inc.
Leukemia, Hodgkin's Lymphoma
Abdominal Obesity and Cardiovascular Risk Factors in Women Who Survived Cancer or a Related Illness Following Total Body Irradiation and Stem Cell Transplant
The purpose of this study is to better understand why some women who survived cancer or a related illness later develop diabetes, problems with their cholesterol, or other problems that may lead to heart disease.
- Conditions
- Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Myelodysplastic Syndrome
- Trial name
- NCT00510315
- Testing
- Questionnaires, Laboratory tests, Abdominal MRI
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Blood Pressure
iPhone App Compared to Standard Riva-Rocci (RR)-Measurement During Stress Testing
The iPARR DELTA BP Study is designed to evaluate whether a new smartphone app using the photoplethysmography signal of the inbuilt camera can measure blood pressure (BP) fluctuations with sufficient correlation compared to the…
- Trial name
- iPARRDeltaBP (NCT02860533)
- Testing
- cuff device, iphone
- Where
- Switzerland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Intradialytic Hypotension, End-stage Renal Disease (ESRD)
Epidemiology And Risk Factors Of Intradialytic Hypotension In Maintenance Hemodialysis Patients
This prospective, multicenter observational study aims to describe how often intradialytic hypotension (IDH) occurs and to identify its risk factors in adult patients receiving maintenance hemodialysis.
- Conditions
- Intradialytic Hypotension, End-stage Renal Disease (ESRD), Chronic Kidney Failure, Chronic Kidney Disease, Stage IV (Severe)
- Trial name
- IDH-MHD (NCT07545629)
- Where
- China
- Volunteers
- 395 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Cerebral Stroke, Thrombosis, Deep Vein
A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
To characterize and analyze the number, type and incidence of adverse events/suspected adverse drug reactions in patients treated with Apixaban, according to therapeutic indications approved in Mexico.
- Conditions
- Cerebral Stroke, Thrombosis, Deep Vein, Pulmonary Embolism
- Trial name
- NCT03804125
- Sponsor
- Pfizer
Hypertension, Atherosclerosis
Age-Related Changes in Body Composition
Background: Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age.
- Trial name
- NCT01517113
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Cardiovascular Risk Factor, Menopause Related Conditions
The Clinical Utility of Resistance Training for Improving Cardiovascular Disease Risk in Post-Menopausal Women
Given the heightened cardiovascular disease (CVD) risk in post-menopausal women, studies are needed to explore novel, feasible methods for reducing risk in this population.
- Conditions
- Cardiovascular Risk Factor, Menopause Related Conditions, Neuromuscular Function, Aerobic Capacity
- Trial name
- NCT03752060
- Testing
- Resistance Exercise, Aerobic Exercise
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Obesity, Morbid, Hypertension
Comparison of Extremely Obese Patients Undergoing Gastric Sleeve Surgery
By the comparison of the preoperative and postoperative data of approximately 160 patients undergoing gastric sleeve surgery, we try to draw conclusions about the effectiveness of gastric sleeve surgery, expected complication…
- Conditions
- Obesity, Morbid, Hypertension, Diabetes Mellitus, Type 2
- Trial name
- NCT05929170
- Where
- Hungary
- Volunteers
- 160 people
- Sponsor
- University of Pecs
Kidney Transplant Recipients, Metabolic Syndrome
Velocity-Based Resistance Training in Kidney Transplant Recipients
This randomized controlled trial aims to evaluate the effects of velocity-based resistance training on renal function and metabolic health in kidney transplant recipients.
- Conditions
- Kidney Transplant Recipients, Metabolic Syndrome, Cardiovascular Risk Factors
- Trial name
- VBRTKIDNEY (NCT07370727)
- Testing
- Velocity-Based Resistance Training - Submaximal Velocity Protocol, Velocity-Based Resistance Training - Maximal Velocity Protocol
- Where
- Colombia
- Volunteers
- 12 people
- Sponsor
- Fundación Universitaria del Area Andina
Cigarette Smoking, Coronary Heart Disease
Exercise and Coronary Heart Disease Risk Markers in Male Smokers and Non-Smokers
The present study will investigate the effect of acute exercise on fasting and postprandial risk markers for coronary heart disease (CHD) in healthy male cigarette smokers and non-smokers.
- Conditions
- Cigarette Smoking, Coronary Heart Disease, Cardiovascular Risk Factor, Insulin Resistance
- Trial name
- NCT03735186
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Cardiovascular Diseases
Evaluating the Effect of Neighborhood Environments on Cardiovascular Risk Factors
Cardiovascular disease (CVD) is one of the main causes of death in the United States. Research has shown that individuals who maintain an active lifestyle are less likely to develop CVD.
- Trial name
- NCT00361673
- Where
- 2 sites in United States
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Weight Loss, Obesity
A Grapefruit Feeding Trial in Healthy, Overweight Adults
Folklore has suggested that consuming grapefruit may promote weight control. Sparse data exist to support this hypothesis, though there is some evidence of health promotional effects regarding blood pressure and lipid profiles.
- Conditions
- Weight Loss, Obesity, Cardiovascular Risk Factors
- Trial name
- NCT01452841
- Testing
- Grapefruit, Control
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hypertension
Effects of Blackberry-derived Polyphenols on Cardiovascular Risk in Adults
Cardiovascular disease (CVD) is the most common cause of death in Ireland, accounting for 33% of all deaths. Hypertension or elevated blood pressure, is also a significant health problem, however, it is one of the major…
- Trial name
- Cardio-Rubus (NCT02355444)
- Testing
- blackberry polyphenol enriched beverage, blackberry beverage with minimal polyphenol concentrations
- Where
- Ireland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University College Cork
Pulmonary Embolism, Deep Venous Thrombosis
Prevalence of Pulmonary Embolism in ICU
The primary objective of this study was to estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was…
- Trial name
- PEICU (NCT01457963)
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Grenoble
Cardiovascular Risk Factor
Intensive Intervention to Improve Lifestyles in Subjects With Intermediate Cardiovascular Risk.
This is a randomized controlled trial aimed to design an intensive intervention to modify lifestyles of subjects with intermediate cardiovascular risk and evaluate its effectiveness.
- Trial name
- NCT03164499
- Testing
- Individual counselling on lifestyles, Additional group counselling on lifestyles
- Where
- Spain
- Volunteers
- 203 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Gastrointestinal Hemorrhage, Cardiovascular Diseases
Study of the Risk Factors and Outcomes After Gastrointestinal Bleeding
The purpose of this multicenter, two component observational and standardized case-control study is to evaluate risk factors of gastrointestinal (GI) bleeding with a prospective 3-month and 12-month follow-up to examine outcomes…
- Trial name
- NCT02514304
- Where
- Canada
- Volunteers
- 4,745 people
- Sponsor
- Population Health Research Institute
Diabetes Mellitus, Type 2
A Study of People With Type 2 Diabetes Who Have Diseases That Affect the Heart and Blood Vessels. The Study Will Also Look at the Treatment of a Group of These People in Hospitals in Portugal
This study aims to estimate the number of patients with cardiovascular disease and risk factors in patients who had been diagnosed with type 2 diabetes mellitus.
- Trial name
- PICT2RE (NCT03797885)
- Testing
- No treatment given
- Where
- 14 sites in Portugal
- Volunteers
- 730 people
- Sponsor
- Novo Nordisk A/S
Obstructive Sleep Apnea, Metabolic Syndrome
Effects of CPAP on Cardiovascular Risk in Obstructive Sleep Apnea (OSA) and Metabolic Syndrome
The increased risk of atherosclerotic morbidity and mortality in patients with obstructive sleep apnea (OSA) has been linked to arterial hypertension, insulin resistance, systemic inflammation, and oxidative stress in previous…
- Trial name
- NCT00635674
- Testing
- CPAP device - REMstar Plus, Respironics, Murrysville, USA
- Where
- Slovakia
- Volunteers
- 32 people
- Sponsor
- Pavol Jozef Safarik University
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