Clinical trials: Risk Prediction Model
Acute Ischaemic Stroke, Stroke-associated Pneumonia
Ultra-early Chest CT for SAP Prediction
Stroke-associated pneumonia (SAP) is a common and serious complication after acute ischaemic stroke (AIS). Existing scores rely mainly on clinical variables, and the added prognostic value of inflammatory markers and early chest…
- Trial name
- SENTRY (NCT07321275)
- Where
- 8 sites in China
- Volunteers
- 1,499 people
- Sponsor
- Capital Medical University
Hip Fracture, Hip Fracture Surgeries
External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture
This study aims to externally validate ten existing prediction models with a low risk of bias for 30-day mortality following hip fracture.
- Trial name
- PROTECT (NCT06961253)
- Where
- Netherlands
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- JointResearch
Prostate Cancer (Diagnosis), Clinically Significant Prostate Cancer
Multimodal Imaging and Digital Pathology for Prostate Cancer Prediction
This is a multicenter observational study. A deep learning model integrated with multimodal imaging and digital pathology spatial registration is built based on preoperative multiparametric magnetic resonance imaging, transrectal…
- Trial name
- NCT07614256
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangxi Medical University
Bronchiectasis, Non-cystic Fibrosis Bronchiectasis
BASE: Bronchiectasis Severity and Exacerbation Risk Study
Non-cystic fibrosis bronchiectasis (NCFB) is a chronic airway disease characterized by permanent bronchial dilatation, impaired mucus clearance, recurrent infection, airway inflammation, and repeated exacerbations.
- Conditions
- Bronchiectasis, Non-cystic Fibrosis Bronchiectasis, Bronchiectasis With Acute Exacerbation
- Trial name
- BASE (NCT07599839)
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Assiut University
Pre-Exposure Prophylaxis
Leveraging Electronic Health Record Data in a Risk Prediction Model to Increase HIV PrEP Intake in Primary Care
Kaiser Permanente Northern California (KPNC) has been a national leader in implementation of HIV preexposure prophylaxis (PrEP), a daily antiretroviral pill that is more than 99% effective in preventing HIV acquisition.
- Trial name
- NCT05991869
- Testing
- Point-of-care decision support intervention
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Venous Thromboembolism, Critical Illness
Predicting the Risk of Venous Thromboembolism in Critically Ill Patients
Introduction: Venous thrombosis (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE) remains a frequent complication in patients admitted to the Intensive Care Unit (ICU).
- Trial name
- NCT05498142
- Volunteers
- 7,600 people
- Sponsor
- University Medical Center Groningen
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Oncology
Risk Scoring Model for Endometrial Cancer
A prospective cohort study to assess RHEA ( recurrent vaginal bleeding, hypertension, endometrial thickness and age) scoring model for prediction of endometrial carcinoma
- Trial name
- Cohort (NCT03298100)
- Testing
- Scoring model
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Acute Myocardial Infarction
Risk Prediction Model of MACE in Patients With AMI Based on Multi-modal Machine Learning
A prospective, multicenter, observational study is adopted, with Jiangsu Provincial People's Hospital as the leading unit, and the other 13 Hospitals as cooperative units.
- Trial name
- NCT06767852
- Where
- China
- Volunteers
- 655 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer, Estrogen Receptor-Positive
Validity of Brain Metastasis Risk Predictive Model in Hormone Positive Breast Cancer Patients
This study aims to validate a prediction model of brain metastasis risk for females with HR+ breast cancer by using variables collected at diagnosis.
- Trial name
- NCT06729099
- Volunteers
- 128 people
- Sponsor
- Assiut University
Colorectal Polyp, Colorectal Cancer Recurrent
Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
The characteristics of the intestinal microbiota in high-risk colorectal polyp recurrence and their relationship with disease pathogenesis have not yet been fully elucidated.
- Conditions
- Colorectal Polyp, Colorectal Cancer Recurrent, Colorectal Adenoma
- Trial name
- NCT06957626
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Psoriasis
Prediction Model for Osteopenia in Patients With Psoriasis
This study aims to develop a clinical prediction model for osteopenia in patients with psoriasis. By retrospectively analyzing demographic, laboratory, and lifestyle variables, the investigators will identify risk factors…
- Trial name
- NCT07112755
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongli Yu