Clinical trials: Risk for Metabolic Syndrome
Erythropoietin Resistant Anemia (EPO Resistant Anemia)
" Evaluation of Erythropoietin Therapy in Patients With End-Stage Kidney Disease on Regular Hemodialysis: Hemoglobin Outcomes, and Metabolic Syndrome as a Risk Factor for Erythropoietin Resistance "
The primary aim of this study is to investigate the association between metabolic syndrome and erythropoietin resistance in patients with End-Stage Kidney Disease (ESKD).
- Trial name
- NCT06983756
- Testing
- Erythropoietin
- Volunteers
- 66 people
- Sponsor
- Fayoum University
Exergaming, Metabolic Syndrome
Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
The worldwide increasing of prevalence of non-communicable diseases has grown the recognition of necessity for identifying the modifiable risk in preventing and managing these diseases.
- Trial name
- NCT06556784
- Testing
- 12-week at-home immersive virtual reality exergame
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Guangzhou University
Obesity, Metabolic Syndrome
Effects of Exercise on Abdominal Obesity and Risk Factors for Cardiovascular Disease
The investigators will randomize abdominally obese men and women at increased health risk to one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume, low intensity exercise (LVLI), 3) High volume…
- Conditions
- Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00955071
- Testing
- Exercise: LVLI, Exercise: HVLI, Exercise: LVHI
- Where
- Canada
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Queen's University
Obesity, Body Weight
Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans
This study, at the Western Human Nutrition Research Center (WHNRC), will focus on whether or not achieving and maintaining a healthy body weight is the most important health promoting recommendation of the Dietary Guidelines for…
- Trial name
- DGA4ME (NCT04293224)
- Testing
- DGA Mediterranean diet pattern, energy balance, DGA Mediterranean diet pattern, negative energy balance, TAD diet pattern, negative energy balance
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Diabetes Mellitus, Type 2, PreDiabetes
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease.
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
- Trial name
- TRANSFORM (NCT06112418)
- Testing
- The Cleerly CAD Staging System
- Where
- 125 sites in United States
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Cleerly, Inc.
Metabolic Syndrome, Diabetes
Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome
The goal of this randomized clinical trial is to evaluate the effect of Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome.
- Conditions
- Metabolic Syndrome, Diabetes, Hyperlipidemias
- Trial name
- NCT05566197
- Testing
- Diet Nusantara, Nutrition Counseling
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Metabolic Syndrome Risk Factors, Overweight
Study of Effectiveness of Different Lifestyle Interventions for Health and Wellbeing
The purpose of this study is to examine the effectiveness and applicability of different interventions designed for enhancing overall wellbeing.
- Conditions
- Metabolic Syndrome Risk Factors, Overweight, Psychological Stress
- Trial name
- NCT01738256
- Testing
- Wellbeing intervention (ACT), Wellbeing intervention (Internet), No intervention
- Where
- 3 sites in Finland
- Volunteers
- 339 people
- Sponsor
- University of Jyvaskyla
Metabolic Syndrome
Lifestyle-related Early Detection and Intervention for Older Adults & Elderly at Risk for Metabolic Syndrome
In GATEKEEPER intervention, Big Data Analytics techniques will be exploited to address risk stratification and early detection, based on lifestyles analysis including: pattern recognition for the improvement of public health…
- Trial name
- GATEKEEPER (NCT05031299)
- Testing
- Standard care, Health-promotion application for self-management, Wearables and devices
- Where
- 2 sites in Greece
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Harokopio University
The Focus of Study is to Determine the Waist Circumference Values to Predict Overweight or Obesity
The Sex Specific Waist Circumference Cut Off Points to Predict Overweight or Obesity
The waist circumference (WC) cut off levels of the Caucasian people may not represent the characteristics of different ethnic groups.
- Trial name
- NCT01914640
- Volunteers
- 4,310 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pediatric Obesity, Obesity
OBDIPHY (OBesity DIgital-PHYsical Care Study)
This is a prospective randomized controlled multicentre non-inferiority trial. The aim of this study to evaluate digi-physical care compared to regular physical/in person care and investigate if digi-physical care can be an equal…
- Conditions
- Pediatric Obesity, Obesity, Adolescent Obesity, Lifestyle Risk Reduction
- Trial name
- OBDIPHY (NCT05247918)
- Testing
- Digital-physical care, Treatment as usual
- Where
- 5 sites in Sweden
- Volunteers
- 102 people
- Sponsor
- Göteborg University
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Immunological Status, Healthy Volunteers
Critical Food Ingredients on Immunocompetence to Prevent the Risk and Development of Obesity/Metabolic Syndrome
Double-blind cross-over intervention where the volunteers were randomized into two groups who, after receiving nutritional counseling, received two formulations in the form of a cookie: Group 1, commercial formulation and Group…
- Conditions
- Immunological Status, Healthy Volunteers, Healthy Volunteers - Male and Female
- Trial name
- CricoImNut (NCT07496320)
- Testing
- Administration of a commercial cookie formulation, Immunonutritional_2
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
This phase II trial studies how well an exercise program and continuous Fitbit monitoring work for managing metabolic syndrome and cardiovascular disease risk in patients with prostate cancer that has spread to other places in…
- Conditions
- Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT05054296
- Testing
- Educational Intervention, Exercise Intervention, FitBit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Hyperlipidemia, Metabolic Syndrome X
Low Fat Plant-Based Supplemented Diet Effects on Risk Factors for Chronic Non-communicable Diseases
The effect of a diet free from animal-sourced nutrients on a variety of risk factors for chronic non-communicable diseases in weight reduction programs is not well established.
- Trial name
- LFPBDS2 (NCT02905448)
- Testing
- Low fat plant-based nutrition
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Hiv, HIV Infections
Changes in Weight, Body Composition and Cardiac Risk After Discontinuing Abacavir Treatment in HIV-infected Individuals
Randomized controlled parallel open-label study in people living with HIV and at least 6 month of treatment with dolutegravir/abacavir/lamivudine prior to inclusion.
- Conditions
- Hiv, HIV Infections, HIV Cardiomyopathy, Weight Change, Body
- Trial name
- AVERTAS (NCT04904406)
- Testing
- Dolutegravir / Lamivudine Oral Tablet
- Where
- 2 sites in Denmark
- Volunteers
- 81 people
- Sponsor
- Thomas Benfield
Cardiovascular Diseases, Heart Diseases
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia
This study will evaluate the efficacy of diet and exercise (DE), with and without niacin and fenofibrate, in reducing the cardiovascular risk of patients with HIV lipodystrophy or dyslipidemia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, HIV Infections, Hyperlipidemia
- Trial name
- HeartPositive (NCT00246376)
- Testing
- Diet, Exercise, Niacin
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Baylor College of Medicine
Bipolar Youth Treated With Second-generation Antipsychotics
SGA-induced Metabolic Syndrome in Bipolar Youth
The investigators tested the hypothesis that long-chain omega-3 (LCn-3) fatty acid supplementation will attenuate the adverse cardiometabolic effects of second-generation antipsychotics exposure in first-episode adolescent manic…
- Trial name
- NCT01858948
- Testing
- Omega, Quetiapine fumarate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Cardiovascular Diseases, Metabolic Syndrome
Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
The aim of this study is to investigate the postprandial effects of fat content and fatty acid composition of mixed meals on parameters associated with cardiometabolic diseases.
- Trial name
- NCT05208346
- Testing
- Mixed meals
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Bonn