Clinical trials: Risk of Cardiac Arrhythmias
Atrial Fibrillation (Paroxysmal), Atrial Fibrillation Recurrent
Atrial Fibrillation Ablation Registry
This is a single centre prospective data registry. In this study atrial conduction characteristics of extended surface Electrocardiograms (esECG), biomarkers and genetic analysis will be performed before ablation, before…
- Conditions
- Atrial Fibrillation (Paroxysmal), Atrial Fibrillation Recurrent, Atrial Fibrillation Common Gene Variants
- Trial name
- AFAB (NCT03075930)
- Testing
- Extended Electrocardiogram, Body surface potential map
- Where
- Netherlands
- Volunteers
- 1,250 people
- Sponsor
- Maastricht University Medical Center
Defibrillators, Implantable, Myocardial Infarction
Risk of Life-threatening Heart Rhythm Disturbances in Siblings
The purpose of this study is to determine if heredity influences the risk of life-threatening heart rhythms (ventricular tachycardia and ventricular fibrillation) after heart attack (myocardial infarction).
- Conditions
- Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
- Trial name
- SIBFIB (NCT00498524)
- Testing
- ICD
- Where
- United States
- Volunteers
- 2,047 people
- Sponsor
- Duke University
Atrial Fibrillation
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs).
- Trial name
- NCT02347111
- Testing
- Flecainide, Sotalol
- Where
- 4 sites in United States
- Volunteers
- 162 people
- Sponsor
- University of Illinois Chicago
Atrial Fibrillation, Chronic Kidney Disease
The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function
This study is designed to investigate the role of lipids/lipoproteins as a potential cause for the harmful changes seen in fibrin clot properties with renal dysfunction and atrial fibrillation
- Trial name
- RALiC (NCT04043026)
- Testing
- Statin
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people
- Sponsor
- University of Liverpool
Atrial Fibrillation, Atrial Fibrillation Paroxysmal
Early Diagnosis of Atrial Fibrillation in the Wait-Time Prior to Seeing a Cardiologist
A randomized patient-oriented trial to investigate whether continual symptomatic use of the Kardia Mobile monitoring device is a superior strategy for diagnosing Atrial Fibrillation (AF) in comparison to normal ambulatory…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- CATCH-AF (NCT04302311)
- Testing
- Holter monitoring, Kardia/AliveCor monitoring
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- Victoria Cardiac Arrhythmia Trials
Atrial Fibrillation, Stroke
AFLETES-MRI: A Cardiac and Cerebral Magnetic Resonance Imaging Study in Athletes With Atrial Fibrillation
Participation in exercise improves cardiovascular health. However, long-term endurance exercise may increase the risk of an irregular heart rhythm called atrial fibrillation (AF).
- Trial name
- AFLETES-MRI (NCT06424171)
- Testing
- Cardiac and brain magnetic resonance imaging.
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Atrial Fibrillation, Cardioversion
Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation
Patients with atrial fibrillation undergoing cardioversion will be randomized to undergo transesophageal echocardiography or they will receive warfarin for 3 weeks with an international normalized ratio (INR) value between…
- Conditions
- Atrial Fibrillation, Cardioversion, Cerebrovascular Stroke
- Trial name
- AFTER-CV (NCT01924065)
- Testing
- Cardioversion, Oral Anticoagulant
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Suleyman Demirel University
Hemodialysis
Fibroblast Growth Factor 23 and Risk of Cardiac Arrhythmias in Hemodialysis Patients
Despite recent progress in the field of hemodialysis (HD), mortality remains unacceptably high, particularly due to cardiac arrhythmias.
- Trial name
- FibCA-HD (NCT06668831)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Antonio Bellasi
Sleep Apnea Syndrome, Atrial Fibrillation
Sleep Apnea and Atrial Fibrillation Recurrence
The main aim of this project is to assess the effect of Sleep apnea syndrome (SAS) screening (and treatment if SAS is moderate to severe, defined by an apnea hypopnea index >15 / h) on recurrence of atrial fibrillation (AF) over…
- Trial name
- SAAFIR (NCT02906839)
- Testing
- Intervention group
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
The Jordan Atrial Fibrillation Study: Baseline Risk Scores and One Year Outcome
The Jordanian AF study, the first of its kind in Jordan, will evaluate patients with AF in an in-patient and out-patient settings.
- Trial name
- NCT03917992
- Where
- 8 sites in Jordan
- Volunteers
- 2,020 people
- Sponsor
- Ayman J Hammoudeh, MD, FACC
Atrial Fibrillation, Coronary Artery Disease
Antithrombotic Strategy for AF Patients With High Risk CAD
Anticoagulation therapy is recommended for patients with atrial fibrillation (AF) in order to prevent ischemic stroke and systemic embolism.
- Trial name
- ADAPT AFFIRM (NCT06866665)
- Testing
- Anticoagulation Monotherapy, Combination therapy
- Volunteers
- 1,400 people
- Sponsor
- Yonsei University
Ventricular Tachycardia
Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias.
- Trial name
- NCT03453645
- Testing
- ventricular tachycardia ablation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Cardiac Resynchronization, Biventricular Pacemakers, Artificial
Assessment of Ventricular Arrhythmia Risk After CRT-D Replacement for Patients With Primary Prevention Indication
Cardiac resynchronization therapy (CRT) has been shown to reduce heart failure (HF), hospitalizations and death in patients with left ventricular ejection fraction (LVEF) <35% and wide QRS.
- Conditions
- Cardiac Resynchronization, Biventricular Pacemakers, Artificial, Cardioverter-Defibrillators, Implantable, Device Replacement
- Trial name
- BioCONTINUE (NCT02323503)
- Testing
- CRT-D device replacement
- Where
- 37 sites in Belgium, France and 6 more
- Volunteers
- 289 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation and Flutter
Risk-Based Screening for the Evaluation of Atrial Fibrillation Trial
1. To determine whether a risk-based screening programme for occult paroxysmal atrial fibrillation, involving extended cardiac monitoring in adults with CHA2DS2-VASc score of 3 or greater, increases the detection of new atrial…
- Trial name
- R-BEAT (NCT03911986)
- Testing
- R Test 4 External Loop Recorder
- Where
- Ireland
- Volunteers
- 755 people
- Sponsor
- National University of Ireland, Galway, Ireland
Atrial Fibrillation
Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 80 Years and Over
The aim of the study is to compare, in real life, the risk benefit (including both major bleeding and thrombotic events (TE) and death from any cause) associated with direct oral anticoagulants (DOA) and with anti vitamin K (VKA)…
- Trial name
- PRESAGE-ACO (NCT02286414)
- Testing
- Direct oral antocoagulant: dabigatran, rivaroxaban, apixaban, Vitamin K antagonist: warfarin, fluindione, acenocoumarol
- Where
- France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Stroke, Prevention and Control
An Observational Cross-sectional Study Evaluating the Use of Re-sources and the Sociodemographic and Clinical Characteristics of Patients Diagnosed With Non-valvular Atrial Fibrillation With a Risk of Stroke or Systemic Embolism on Anticoagulant Therapy and Treated in Primary Care Centers
This is a retrospective observational study to describe the sociodemographic and clinical characteristics of patients diagnosed with non-valvular atrial fibrillation (NVAF) at risk of stroke or systemic embolism, who at least…
- Conditions
- Stroke, Prevention and Control, Atrial Fibrillation
- Trial name
- BRONCE-AP (NCT02559232)
- Testing
- Direct Oral Anticoagulant (DOAC)
- Where
- Spain
- Volunteers
- 247 people
- Sponsor
- Bayer
Brugada Syndrome
Hydroquinidine Versus Placebo in Patients With Brugada Syndrome
The specific aim of this study is to determine whether hydroquinidine administration can prevent heart from appearance of ventricular arrhythmia detected by the automatic implantable defibrillator (ICD).
- Trial name
- Quidam (NCT00927732)
- Testing
- hydroquinidine
- Where
- 17 sites in France
- Volunteers
- 64 people
- Sponsor
- Nantes University Hospital
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation
Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy.
To evaluate the progression of atrial myopathy through wearable devices and cardiac imaging.
- Trial name
- TiPP (NCT04703166)
- Testing
- Samsung Galaxy Watch Active2
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Tulane University School of Medicine