Clinical trials: Robotic-assisted Radical Prostatectomy
Prostate Adenocarcinoma, Localized Prostate Carcinoma
Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)
This study is a two-arm, multicenter, randomized controlled clinical trial on whether single-port extraperitoneal VIP RARP is non-inferior to multi-port transperitoneal RARP in terms of functional recovery rate and other key…
- Trial name
- NCT06238713
- Testing
- Single-port extraperitoneal robotic-assisted radical prostatectomy with Vattikuti Institute Prostatectomy（VIP） techniques, Multi-port transperitoneal robotic-assisted radical prostatectomy with bilateral intrafascial nerve-sparing techniques
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Changzheng Hospital
Prostate Cancer, Positron Emission Tomography
Radio-guided Surgery With DROP-IN Beta Probe for 68Ga-PSMA, in High-risk Prostate Cancer Patients Eligible for Robotic-assisted Radical Prostatectomy.
The goal of this observational study is to evaluate the diagnostic efficacy and the safety of the combined approach with β-probe and 68Ga-PSMA-11 PET/CT in the correct identification of lymph node metastases, in high-risk…
- Conditions
- Prostate Cancer, Positron Emission Tomography, PSMA
- Trial name
- NCT05596851
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- European Institute of Oncology
Prostate Cancer, Radical Prostatectomy
Efficacy of the Pelvic Clock® Device for Functional Recovery After Robotic-Assisted Radical Prostatectomy
This randomized controlled trial evaluates the efficacy of the Pelvic Clock® device, a proprioceptive neuromuscular facilitation tool, in accelerating functional recovery following Robotic-Assisted Radical Prostatectomy (RARP).
- Trial name
- NCT07333807
- Testing
- Pelvic Clock®, Standard Pelvic Floor Muscle Training (PFMT)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Hypothermia; Anesthesia
The Comparison of Remimazolam With Propofol in Core Body Temperature
1. Core body temperature is normally tightly regulated to within a few tenths of a degree. The major thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shivering. 2.
- Trial name
- NCT05215834
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Wonkwang University Hospital
Prostate Cancer
The Impact of Low Pressure Pneumo in RARP
The purpose of this study is to evaluate clinical significance of low pressure pneumoperitoneum during robotically assisted radical prostatectomy (RARP).
- Trial name
- NCT03370016
- Testing
- Amount of Pneumoperitoneum Pressure applied during RARP
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Metro Health, Michigan
Prostate Cancer, Erectile Dysfunction
Nerve Grafting Technique to Preserve Erectile Function in Patients Undergoing Robotic Assisted Radical Prostatectomy
The investigator proposing a single arm prospective pilot trial evaluating the safety and the 1-year erectile recovery outcomes of patients undergoing Nerve Restoring (NR) Robotically assisted laparoscopic radical prostatectomy…
- Trial name
- NR-RALP (NCT06521710)
- Testing
- Intraoperative Somatic-Autonomic Nerve Grafting
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Database, Prostate Cancer
National Robotics-Assisted Radical Prostatectomy Database
In Australia, nearly 70 men are diagnosed with Prostate cancer every day. Prostate removal (Radical Prostatectomy) is the proven treatment option to control cancer spread.
- Conditions
- Database, Prostate Cancer, Robotic-assisted Radical Prostatectomy, Surgical Outcomes
- Trial name
- RASOR (NCT06279260)
- Where
- 8 sites in Australia
- Volunteers
- 10,000 people
- Sponsor
- Melbourne Health
Prostate Cancer (Adenocarcinoma)
Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
This is a Phase I/II trial evaluating the effectiveness of adding neoadjuvant HDR-B prior to RALP for HR-PCa patients with selective AAB for decipher high risk or pathologically node positive patients.
- Trial name
- NCT07182279
- Testing
- Brachytherapy
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The Methodist Hospital Research Institute
Prostate Cancer
Laparoscopic vs Robotic-Assisted Radical Prostatectomy
This randomized trial was designed to address the lack of high-quality literature comparing robotic-assisted (RARP) and laparoscopic (LRP) radical prostatectomy (RP).
- Trial name
- LAP-01 (NCT03682146)
- Testing
- Prostatectomy
- Where
- 4 sites in Germany
- Volunteers
- 782 people
- Sponsor
- University of Leipzig
Robot-Assisted Radical Prostatectomy
Effect of Control Ventilation, PEEP, and PEEP With ARM in Robot-assisted Radical Prostatectomy
The goal of this clinical trial is to determine whether different ventilatory strategies improve oxygenation and hemodynamic stability in patients undergoing robot-assisted radical prostatectomy under general anesthesia.
- Trial name
- NCT07462689
- Testing
- PEEP group, PEEP + ARM group
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ilsan Cha hospital
Myocard Injury After Non Cardiac Surgery, Robotic Assisted Laparoscopic Radical Prostatectomy
PERIOPERATIVE MYOCARDIAL DAMAGE IN ROBOT-ASSISTED SURGERY
Our study aimed to identify myocardial damage during or after robotic-assisted radical prostatectomy by measuring high-sensitive Troponin I levels, which are the most sensitive and effective according to the AHA/ACC guideline.
- Trial name
- NCT06502340
- Testing
- high sensitive troponin I
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Hypotension During Surgery
Hypotension Prediction Index (HPI) in Patients Undergoing Robotic Assisted Radical Prostatectomy
Robot assisted radical prostatectomy (RARP) is the leader in robotic treatment for prostate cancer. Goal-directed therapy (GDT) is the approach used, but HPI, a machine learning algorithm analysing arterial waveforms, might offer…
- Trial name
- HPI in RARP (NCT06535464)
- Testing
- Hypotension Prediction Index, No Hypotension Prediction Index
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Foggia
Prostate Cancer, Urinary Incontinence
Prospective RCT on Post Prostatectomy Urine Leak
Objectives: Primary: Comparison of proportion of patient achieving continence between the four arms at 6 months. Secondary: Comparison of time to achieve continence between the four arms.
- Trial name
- NCT02367404
- Testing
- Duloxetine, Pelvic Floor Muscle Training
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut Mutualiste Montsouris
Prostate Cancer
Effect of Mannitol on Optic Nerve Sheath Diameter in Patients Undergoing Robotic Prostatectomy
We aim to evaluate the change in optic nerve sheath diameters as a surrogate of intracranial pressure before and after mannitol administration in patients who undergo robot assisted laparoscopic radical prostatectomy with…
- Trial name
- NCT03214055
- Testing
- Mannitol
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Asan Medical Center
Robot-Assisted Radical Prostatectomy Training, Prostatectomy
Comparing Two Training Methods for Learning Robot-Assisted Radical Prostatectomy
This randomized non-inferiority study evaluates whether a robot-assisted radical prostatectomy (RARP) training pathway incorporating the IMRA Surgical Prostatectomy Class V Hydrogel Model is as effective as the current standard…
- Trial name
- NCT07669974
- Testing
- IMRA-Enhanced Training Pathway, Standard Training Pathway
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Orsi Academy
Prostate Cancer
Randomized AmnioFix Study During Radical Prostatectomy
The goal of this clinical research study is to learn about the safety and the effectiveness of using AmnioFix® (dehydrated human amnion/chorion membrane, also called dHACM) to help improve the return of erectile function and…
- Trial name
- NCT02645591
- Testing
- Robotic Assisted Laparoscopic Radical Prostatectomy (RARP), AmnioFix®, Questionnaire
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Ability of Cardio Q for Prediction of Hypotension
Evaluation the ability of each indicator of Cardio Q in predicting hypotension after position changes in robot-assisted laparoscopic radical prostatectomy
- Trial name
- NCT03882697
- Where
- 2 sites in South Korea
- Volunteers
- 125 people
- Sponsor
- Severance Hospital
Cerebral Hemodynamics, Mechanical Ventilation Strategies
Cerebral Hemodynamic Effects of Individualized PEEP During Robotic Prostatectomy
This randomized clinical trial will compare two approaches to setting positive end-expiratory pressure (PEEP) during robot-assisted radical prostatectomy performed in the Trendelenburg position.
- Conditions
- Cerebral Hemodynamics, Mechanical Ventilation Strategies, Robotic Prostatectomy
- Trial name
- NCT07784010
- Testing
- Individualized PEEP Titration, Standard PEEP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Erectile Dysfunction Following Radical Prostatectomy
Intracavernosal Exosomes vs. Rectal Ozone for Post-RARP Erectile Dysfunction
This prospective, randomized, controlled trial aims to evaluate and compare the therapeutic efficacy of intracavernosal urine-derived exosomes and systemic rectal ozone therapy in patients experiencing erectile dysfunction (ED)…
- Trial name
- REHAB-RARP (NCT07707505)
- Testing
- Urine-Derived Exosomes (USC-Exos), Rectal Medical Ozone Insufflation, Daily Phosphodiesterase type 5 (PDE5) Inhibitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Prostate Cancer
Robot-assisted vs Laparoscopic Radical Prostatectomy for Prostate Cancer Treatment
This study is to compare the outcomes of robotic-assisted laparoscopic radical prostatectomy (RARP) and laparoscopic radical prostatectomy (LRP) for prostate cancer treatment in terms of perioperative surgical, functional and…
- Trial name
- NCT04011865
- Testing
- Radical prostatectomy
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Binh Dan Hospital