Clinical trials: Root Canal Infection
Pulp Disease, Dental, Obturation
Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling
Preserving primary teeth is essential for many aspects such as the child's growth and development, esthetic, functional, psychological, and dental arch integrity aspects.
- Conditions
- Pulp Disease, Dental, Obturation, Root Canal Infection
- Trial name
- NCT05633537
- Testing
- pulpectomy procedure and the clinical evaluation, radiographic evaluation
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Anal Canal HPV Infection Diagnosis, Anal Dysplasia Diagnosis
Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test
This is a study to determine if HC2 HPV testing in the anal canal can detect high-risk HPV and whether this aids in identifying individuals are risk for anal cancer or precancerous lesions.
- Conditions
- Anal Canal HPV Infection Diagnosis, Anal Dysplasia Diagnosis, Anal Cancer
- Trial name
- NCT01104181
- Testing
- HC2 collection kit with a swab or brush
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Laser Surgery Care
Dental Pulp Necrosis, Periapical Abscess
Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.
This Study Was Made to Evaluate the Antibacterial Effect of Different Antibacterial Combinations on Revascularization Process in Permanent Anterior Immature Teeth.
- Conditions
- Dental Pulp Necrosis, Periapical Abscess, Root Canal Infection
- Trial name
- NCT03533231
- Testing
- Canal Disinfection Triple Antibiotic Paste (TAP), Ciprofloxacin + Propolis Paste, Ciprofloxacin + Metronidazole Paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tariq Yehia
Endodontically Treated Teeth, Root Canal Infection
Tooth Crown Discoloration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Root Canal Infection, Tooth Discoloration
- Trial name
- NCT03841370
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Otomycosis
Comparative Efficacy of Topical Clotrimazole Versus 2% Salicylic Acid in Otomycosis
Otomycosis is a fungal infection of the outer ear canal that commonly causes itching, discomfort, discharge, and a feeling of blockage in the ear.
- Trial name
- NCT07535424
- Testing
- clotrimazole, 2% Salicylic Acid
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mayo Hospital Lahore
Periapical Periodontitis
Safety and Efficacy of the Apexum Ablator
The study is designed to test the hypothesis that there is a difference in healing kinetics and healing rate between teeth treated by conventional endodontic procedure alone and those in which such procedure was supplemented with…
- Trial name
- NCT00762840
- Testing
- the Apexum Protocol, Conventional endodontic procedure
- Where
- 2 sites in Romania
- Volunteers
- 100 people
- Sponsor
- Apexum Ltd.
Periapical Periodontitis
Antibacterial Effectiveness of Two Root Canal Irrigants
The aim of this randomized clinical trial is to compare the antibacterial effects of 1% sodium hypochlorite (NaOCl) and 2% chlorhexidine gluconate (CHX) during retreatment of teeth with apical periodontitis (AP).
- Trial name
- NCT02747082
- Testing
- Retreatment of root-filled teeth with infection
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- University of Oslo
Endodontic Disease, Root Canal Infection
Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection
The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments.
- Trial name
- NCT05959629
- Testing
- Waterlase Express™, BIOLASE®, Sodium Hypochlorite
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Escherichia Coli Infections
Detection of Biofilm Among Uropathogenic Escherichia Coli Clinical Isolates in Suez Canal University Hospitals
This descriptive cross-sectional study will beconducted in Suez Canal University Hospitals (SCUHs) in Ismailia, Egypt. The study aims to detect Escherichia coli biofilm producers to improve prognosis and treatment and reduce…
- Trial name
- NCT06252428
- Where
- Egypt
- Volunteers
- 47 people
- Sponsor
- Suez Canal University
Effects of; Cold
Role of Cryotherapy in Reduction of Post Operative Endodontic Pain Following Single Visit Root Canal Therapy
AIM : To determine the efficacy of cold saline irrigation in reduction of post operative pain following root canal therapy. METHODOLOGY : Forty patients requiring root canal treatment on permanent single rooted teeth were…
- Trial name
- NCT03044470
- Testing
- cryotherapy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mamata Dental College
Root Canal Infection
Postoperative Pain After Using a Minimally Invasive Reciprocating Single-file System in Mandibular Molars With Symptomatic Irreversible Pulpitis
The aim of the present study is to assess the incidence and severity of postoperative pain after root canal preparation of mandibular molars with symptomatic irreversible pulpitis using a minimally invasive reciprocating…
- Trial name
- NCT07718607
- Testing
- Reciprocating rotary single-file system, Wave One Gold rotary file system
- Volunteers
- 56 people
- Sponsor
- Minia University
Apical Periodontitis, Dental Pulp Necrosis
Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial)
The goal of this clinical trial is to learn which of three common root-canal rinsing (irrigation) methods removes bacteria most effectively in adult patients who need root-canal treatment.
- Conditions
- Apical Periodontitis, Dental Pulp Necrosis, Root Canal Infection
- Trial name
- CHITO-PRE RCT (NCT07048028)
- Testing
- Chitosan Low Molecular Weight (20-200 Mpa.S), Sodium Hypochlorite, EDTA chelating agents
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ESRA DAĞCI
Periapical; Infection
Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators
Calcium hydroxide is generally preferred in endodontics as an intracanal medicament because of its antimicrobial and biological effects. However, the antimicrobial effect of calcium hydroxide is limited.
- Trial name
- NCT06307678
- Testing
- Calcium Hydroxide, Calcium Silicate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University