Clinical trials: Root Canal Therapy
Apical Periodontitis
Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis
This clinical study aimed to Compare the levels of Interleukin 8 before and after root canal treatment in patients with apical periodontitis Diagnosis Local anesthesia Isolation and disinfection of the tooth Two-staged access…
- Trial name
- NCT05653947
- Testing
- Root canal instrumentation, 2.5% NaOCl irrigation
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apical Lesion
The Effect of Injectable Platelet Rich Fibrin on Apical Lesion Healing
In recent years, the use of autologously obtained blood products that stimulate cell proliferation, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), has become increasingly widespread.
- Trial name
- NCT07876427
- Testing
- i-PRF, root canal treatment and intracanal medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hande Has Elçi
Pulpitis - Irreversible
Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment
Pulpotomy has been proposed in the last decade as a definitive treatment of mature permanent teeth with irreversible pulpitis due to the better understanding of the pulp biology and development of bioactive materials .
- Trial name
- NCT03916900
- Testing
- Pulpotomy, Root canal treatment
- Volunteers
- 52 people
- Sponsor
- Cairo University
Post Operative Pain
Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used.
- Trial name
- PEP (NCT03448263)
- Testing
- Balanced Force technique, WaveOne technique, Reciproc technique
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Chronic Apical Periodontitis, Periapical Healing
MMP-2/3 and Periapical Healing Outcomes
This prospective randomized clinical study will investigate the association between MMP-2 and MMP-3 gene polymorphisms and radiographic healing outcomes following nonsurgical root canal treatment in patients with chronic apical…
- Trial name
- NCT07529964
- Testing
- Nonsurgical Root Canal Treatment
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Irreversible Pulpitis, Mature Teeth
Effectiveness of Pulpotomy in the Management of Mature Permanent Tooth With Irreversible Pulpits
This study is to evaluate the effectiveness of pulpotomy in mature permanent tooth with irreversible pulpits, and compare the clinical efficacy of pulpotomy and root canal therapy.
- Trial name
- NCT05622266
- Testing
- Pulpotomy, Root Canal Therapy
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Liver Cirrhosis, Periapical Lesions
Oral Health Status in Patients With Cirrhosis and Effect of Dental Treatment on MELD Score of Cirrhosis Patients
It has been found that there is an association between prevalence of odontogenic infection and systemic diseases.Cirrhosis has also been associated with poor oral health status.Treating those patients accordingly can help in…
- Trial name
- NCT04399512
- Testing
- Nonsurgical root canal treatment
- Where
- India
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Liver Metastases, Colorectal Cancer
Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases
This is a Phase II study to determine the efficacy of SBRT to treat liver metastases in patients with Colorectal Adenocarcinoma, Carcinoma of the Anal Canal and Gastrointestinal Neuroendocrine Tumors that are not amenable to…
- Conditions
- Liver Metastases, Colorectal Cancer, Anal Canal Cancer, Gastrointestinal Neuroendocrine Tumors
- Trial name
- NCT02185443
- Testing
- SBRT
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- University of Sao Paulo
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Endodontic Disease, Root Canal Infection
Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection
The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments.
- Trial name
- NCT05959629
- Testing
- Waterlase Express™, BIOLASE®, Sodium Hypochlorite
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
LUMBAR STENOSIS
Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Stenosis of symptomatic lumbar canal is presented as a series of degenerative changes affecting the various vertebral segment structures, including: a joint zigoapofisária, yellow ligament, the articular capsule and the…
- Trial name
- Stenosis (NCT02879461)
- Testing
- LUMBAR DESCOMPRESSION
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Federal University of São Paulo
Periapical Lesions
Glycemic Levels on Healing of Periapical Lesions in Type 2 Diabetic Patients
Increased incidence of peri-radicular lesions have been reported in diabetic patients which has been implicated due to compromised immune response.
- Trial name
- NCT04355988
- Testing
- Nonsurgical root canal therapy
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Apical Periodontitis
The Aim of This Study is to Evaluate the Relationship Between Genetic Polymorphisms and Periapical Lesion Healing in Individuals With Chronic Apical Periodontitis at Clinical and Radiological Levels.
Chronic apical periodontitis is a chronic inflammatory condition characterized by periapical tissue destruction and alveolar bone resorption as a result of the host response to pulpal infection, often presenting asymptomatically.
- Trial name
- NCT07542223
- Testing
- single nucleotide polymorphism
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ataturk University