Clinical trials: Ropivacaine
Overweight and Obesity, Bariatric Surgery Candidate
Intraperitoneal Local Anesthetic in Bariatric Surgery Study (iLABS Study)
Obesity is a metabolic disorder that has gradually become a prevalent public health problem and is becoming one of the leading causes of death and disability worldwide.
- Trial name
- NCT03175081
- Testing
- Ropivacaine, Normal saline
- Where
- 2 sites in Malaysia
- Volunteers
- 54 people
- Sponsor
- Dr. Tikfu Gee
Major Ankle Surgery
Saphenous Nerve Block: Single Shot Versus Continuous Infusion to Supplement a Continuous Sciatic Nerve Block After Major Ankle Surgery
The most useful method to manage pain after major ankle surgery is infusion of local analgesics with a catheter close to the sciatic nerve.
- Trial name
- NCT01445210
- Testing
- Continuous saphenous nerve block
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Pain, Arthroplasty, Replacement, Knee
Comparison of Levobupivacaine and Ropivacaine for Femoral Neural Block
The anaesthetic management of patients undergoing total knee replacement is still not standardised. Epidural analgesia is common, but is associated with bilateral lower limb motor block and limited mobilisation.
- Trial name
- NCT01172197
- Testing
- Levobupivacaine, Ropivacaine
- Volunteers
- 14 people
- Sponsor
- NHS Tayside
Hip Arthropathy, Hip Osteoarthritis
PENG Block Optimization: Volume and Dexamethasone Effects
This randomized controlled trial investigates the impact of local anesthetic volume and perineural dexamethasone on the analgesic and anti-inflammatory effectiveness of the pericapsular nerve group (PENG) block in patients…
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Arthritis
- Trial name
- NCT07023120
- Testing
- Ropivacaine 0.2% Injectable Solution, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Poznan University of Medical Sciences
Obstetric Pain
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient…
- Trial name
- NCT03502642
- Testing
- wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain), Spinal Anesthesia, intrathecal morphine
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Postoperative Pain
Ropivacaine After Sternotomy
Continuous ropivacaine infusion to sternotomy wound after coronary artery bypass grafting (CABG) or heart valve surgery to diminish postoperative pain.
- Trial name
- NAROSYD (NCT02449486)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital
Rotator Cuff Tears, Shoulder Pain
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
This study is a comparison of analgesia effect from peripheral nerve blockade (PNB) with liposomal bupivacaine combined with bupivacaine compared to PNB with ropivacaine combined with dexamethasone for arthroscopic rotator cuff…
- Trial name
- NCT04737980
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery Florida
Pain
Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery
Nerve blocks are used to decrease the amount of pain you have after surgery. We are asking you to take part in a research study.
- Trial name
- NCT01986751
- Testing
- Clonidine, ropivacaine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Alabama at Birmingham
Gastric Cancer
Ropivacaine-Poloxamer 407 Gel for Pain Control After Open Gastrectomy
The study evaluates the efficacy of Ropivacaine-Poloxamer 407 hydrogel in reducing postoperative pain following open gastrectomy.
- Trial name
- NCT06778954
- Testing
- Arm I (Peritoneal application group), Arm II (Subcutaneous injection group)
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Gangnam Severance Hospital
Anesthesia; Adverse Effect, Spinal and Epidural, Anaesthetic Complication Neurological
Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Consenting patients, scheduled for orthopaedic surgery under spinal anesthesia will be randomly assigned (1:1) to receive ropivacaine or bupivacaine as a single shot before the start of surgery, followed by bolus doses of the…
- Trial name
- BuRoNe (NCT03293472)
- Testing
- Ropivacaine, Bupivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Postoperative Pain
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
The cesarean section is one of the most commonly performed surgeries in the world and it represents 20% of the births in France. Postoperative pain is moderate-to-severe during the first 48 hours after this procedure.
- Trial name
- ROMANCE (NCT02410317)
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Grenoble
Osteoarthritis, Hip
Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA).
- Trial name
- NCT02359136
- Testing
- local infiltration anesthesia using Ropivacaine and Epinephrine, local infiltration anesthesia using saline, Multimodal analgesic regimen
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Pain, Postoperative
Preemptive Co-infiltration of Triamcinolone Acetonide With Ropivacaine for Postoperative Pain in Major Spinal Surgery
Patients undergoing major spinal surgery usually experience moderate to-severe postoperative pain. Inadequate pain control may lead to severe complications.
- Trial name
- NCT06801587
- Testing
- Triamcinolone acetonide plus ropivacaine, Ropivacaine alone
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Fang Luo
Subgluteal Sciatic Block
Ropivacaine Versus Ropivacaine Plus Mepivacaine for Sciatic Block
In loco regional anesthesia, much more than for general anesthesia, the choice of the product is largely left at the discretion of the practitioner.
- Trial name
- NCT00567450
- Testing
- ropivacaine, ropivacaine plus mepivacaine
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Healthy Volunteers
Effect of Systemic Ropivacaine on Hyperalgesia, Flare Reaction and Peripheral Nerve Excitability
The purpose of this study is to compare the effect of intravenous ropivacaine and lidocaine on the receptive field of primary sensory afferents and their influence on the vascular bed. *Trial with medicinal product
- Trial name
- NCT00900913
- Testing
- ropivacaine (Naropin)
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- University of Zurich
Upper Extremity
Clinical Research of Retrograde Infraclavicular Brachial Plexus Blockade
Brachial plexus block is a frequently used technique for upper extremity surgery. All present approaches and techniques have certain advantages and disadvantages.
- Trial name
- RIBPA (NCT01075503)
- Testing
- brachial plexus block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Jishuitan Hospital
Lower Limb Injuries
Comparative Study of Bupivacaine and Ropivacaine in Lumber Epidural Lower Limb Bypass Surgery
Regional anaesthesia is an important part in clinical anaesthesiology now a day. Epidural block is a commonly used regional technique alternative for general anaesthesia in case of lower limb bypass surgery.
- Trial name
- NCT06677697
- Testing
- Ropivacaine 0,5%
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- ibrahim cardiac hospital and research institute
Inguinal Hernia
Antalgic Efficacy of CycloMesh™ Soaked in Ropivacaine Hydrochloride in Uncomplicated Inguinal Hernia.
CycloMesh is a polyester visceral implant functionalized by drug delivery systems directly on its surface, targeting a unique intervention, a slow anesthetic release and an in situ activity.
- Trial name
- HENRI (NCT04033055)
- Testing
- Inguinal hernia repair with CycloMesh™ soaked in ropivacaine hydrochloride 10mg/mL, Inguinal hernia repair with CycloMesh™ soaked in saline solution NaCl 9°/°°
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Quanta Medical
Duration of Interscalene Block
The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine
Patients undergoing rotator cuff repair or subacromial decompression at the investigators institution are frequently hospitalized overnight due to inadequate pain relief after resolution of interscalene brachial plexus blocks.
- Trial name
- NCT01495624
- Testing
- ropivacaine plus dexamethasone anesthetic, ropivacaine plus saline plus dexamethasone anesthetic
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Inguinal Hernia
The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients
To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
- Trial name
- NCT06218160
- Testing
- Hydromorphone combined with ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Hospital of Jilin University