Clinical trials: Rosacea
Rosacea, Sensitive Skin
Clinical Benefit of M89PB in Subjects With Rosacea Associated With Erythema and Sensitive Skin
The aim of the study is to assess the efficacy of the product M89 probiotic fractions in improving the symptoms of rosacea patients with sensitive skin after 30 days of treatment, in comparison with an area treated with the…
- Trial name
- NCT04898582
- Testing
- Mineral 89 Probiotic Fractions
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute of Skin and Product Evaluation, Italy
Rosacea, Papulopustular Rosacea
Photodynamic Therapy for Papulopustular Rosacea
Rosacea is a chronic inflammatory disorder that is characterized by severe flushing (transient erythema), non-transient erythema, papules, pustules, and telangiectasia.
- Trial name
- NCT02075671
- Testing
- Aminolevulinic acid topical solution 20%, Blu-U Light Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Papulopustular Rosacea
A Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib (LOU064) in Adult Patients With Papulopustular Rosacea (PPR)
This Phase 2 study aims to evaluate whether Bruton's tyrosine kinase (BTK) inhibition with remibrutinib can produce a clinically meaningful reduction in inflammatory lesions in adults with moderate-to-severe papulopustular…
- Trial name
- NCT07681271
- Testing
- LOU064
- Where
- 12 sites in United States, Bulgaria and 6 more
- Volunteers
- 100 people
- Sponsor
- Novartis Pharmaceuticals
Ocular Rosacea
Efficacy and Safety of Dextenza Compared to Topical Fluorometholone in Patients With Ocular Rosacea
To determine patient preference and treatment outcomes with an intracanalicular dexamethasone (0.4mg) insert compared to a standard steroid drop regimen in the contralateral eye for the treatment of ocular rosacea.
- Trial name
- NCT04839549
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Fluoromethalone .01%
- Sponsor
- Eye Associates of Central Texas
Inflammatory Rosacea
Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea
The aim of this trial is to assess the efficacy of Metronidazole Topical Gel 1% in the Treatment of Inflammatory Lesions of Rosacea.
- Trial name
- NCT01016782
- Testing
- 0444
- Volunteers
- 867 people
- Sponsor
- Fougera Pharmaceuticals Inc.
Rosacea
Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
A long-term, open-label, non-comparative safety and efficacy study of CD07805/47 gel 0.5% once daily in subjects with moderate to severe facial erythema associated with rosacea.
- Trial name
- NCT01318733
- Testing
- CD07805/47 gel 0.5%
- Where
- 27 sites in United States
- Volunteers
- 449 people
- Sponsor
- Galderma R&D
Rosacea
A Study of Patient Concerns and Treatment Satisfaction in Patients Being Treated With Finacea Foam for Rosacea
To survey rosacea patients about their concerns, treatment satisfaction, and quality of life associated with their Finacea Foam treatment
- Trial name
- NCT03193372
- Testing
- Azelaic Acid (Finacea Foam, BAY39-6251)
- Where
- United States
- Volunteers
- 2,200 people
- Sponsor
- LEO Pharma
Rosacea
A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Rosacea
This clinical study is to determine the optimum dose of PAC-14028 cream in a therapeutic confirmatory clinical study by evaluating the safety and therapeutic equivalence of PAC-14028 cream 0.1%, 0.3% and 1.0% in patients with…
- Trial name
- NCT02583009
- Testing
- PAC-14028 cream 0.1%, PAC-14028 cream 0.3%, PAC-14028 cream 1.0%
- Where
- South Korea
- Volunteers
- 216 people
- Sponsor
- Amorepacific Corporation
Rosacea
Mirvaso® Utilisation and Patient Satisfaction Evaluation (MUSE)
The aim of the study is to evaluate the level of satisfaction among patients to whom Mirvaso® / Onreltea TM (trade mark) is prescribed.
- Trial name
- MUSE (NCT02637232)
- Testing
- Mirvaso® / Onreltea TM
- Where
- Canada
- Volunteers
- 301 people
- Sponsor
- Galderma R&D
Erythema, Rosacea
Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea
The purpose of this study is to compare the efficacy and assess the safety of CD07805/47 gel 0.5% applied topically once daily versus azelaic acid gel 15% applied topically twice daily in subjects with moderate to severe facial…
- Trial name
- NCT01659853
- Testing
- CD07805/47 gel 0.5%/CD07805/47 Vehicle, azelaic acid gel 15%
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Ocular Rosacea, Antimicrobial Resistance
Ocular Rosacea Biome Study
Ocular rosacea is an inflammatory disease of the eyelids and ocular surface. Like the facial disease, the ocular condition is chronic and recurrent. Sequelae of ocular rosacea vary from mild to severe.
- Trial name
- ORBS (NCT05296837)
- Testing
- Doxycycline 40 MG ( 20mg twice daily), Doxycycline 200 MG ( 100 mg twice daily)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Dermatitis, Atopic, Rosacea
A Study of a Polymeric Surfactant Technology Cleanser in Sensitive Skin Participants
The purpose of this study is to evaluate the efficacy and tolerance of a gentle facial cleanser in participants with sensitive skin (eczema/atopic dermatitis, rosacea, acne, cosmetic intolerance syndrome).
- Conditions
- Dermatitis, Atopic, Rosacea, Acne Vulgaris, Sensitive Skin
- Trial name
- NCT05094700
- Testing
- Non-marketed Cosmetic Facial Cleanser
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Chalazia, Chalazion
Intralesional Tetracycline Injection in the Treatment of Chalazia
The investigators propose a study to investigate the role of tetracycline injection into chalazia versus observation alone. The investigators hypothesize tetracycline injection will result in a significant decrease in lesion size…
- Trial name
- TET (NCT01763437)
- Testing
- Tetracycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Rosacea
Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea
Rosacea is one of the most commonly occurring dermatoses treated by dermatologist today. Rosacea is an inflammatory condition of the skin presenting as flushing and or blushing along with redness, swelling, telangiectasia, and…
- Trial name
- NCT05014906
- Testing
- Minocycline 45 MG, Azelaic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dermatology Specialists Research
Rosacea, Acne
Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases.
- Conditions
- Rosacea, Acne, Centella, Melasma
- Trial name
- NCT06763367
- Testing
- Face mask containing Centella sinensis
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Lipid Keratopathy, Penetrating Keratoplasty
Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal Neovasculization
1. Purpose:Our animal study demonstrated the effectiveness of subconjunctival injection of bevacizumab in the inhibition of corneal neovasculization formation.
- Conditions
- Lipid Keratopathy, Penetrating Keratoplasty, Herpetic Keratopathy, Rosacea
- Trial name
- NCT00681603
- Testing
- subconjunctival injection of bevacizumab ( 1.25 to 2.50 mg)
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
Papulopustular Rosacea
Safety and Efficacy of Rifaximin in Patients With Papulopustular Rosacea and Positive Lactulose Breath Test
Preliminary evidence suggests that treatment with rifaximin may be beneficial in patients with papulopustular rosacea. The present clinical trial is aimed to investigate the safety and efficacy of oral rifaximin delayed release…
- Trial name
- NCT03864978
- Testing
- Rifaximin delayed release 400 mg tablet
- Where
- 12 sites in Italy
- Volunteers
- 236 people
- Sponsor
- Alfasigma S.p.A.
Rosacea
PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With Rosacea
The investigators aim is to investigate the incidence of headache and rosacea-like flushing after pituitary adenylate cyclase-activating peptide-38 (PACAP38) with and without treatment with sumatriptan in patients with rosacea
- Trial name
- NCT03878784
- Testing
- Imigran, Isotonic Saline
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Danish Headache Center
Corneal Neovascularization
Treatment of Corneal Neovascularization With Topical Pazopanib
The purpose of this study is to determine the safety and efficacy of a drug [Pazopanib (Votrient)] as a treatment for corneal neovascularization.
- Trial name
- NCT01257750
- Testing
- Pazopanib (5mg/ml)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Reza Dana, MD
Acne Rosacea
Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study
The pilot study will investigate whether combination treatment of Finacea 15% Gel and Brimonidine 0.33% Gel could be more effective than Brimonidine 0.33% Gel monotherapy in treating both the papules/pustules and erythema…
- Trial name
- NCT02147691
- Testing
- Azelaic acid 15%, Brimonidine 0.33%
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Derm Research, PLLC