Clinical trials: Rosacea
Papulopustular Rosacea
A Twelve Week Safety and Efficacy Study in Rosacea
The purpose of this study is to evaluate th safety and efficacy of one-daily topical application of CLS001 low, mid and high dose compared to vehicle gel in subjects with papulopustular rosacea.
- Trial name
- NCT01784133
- Testing
- omiganan
- Where
- 17 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maruho Co., Ltd.
Rosacea
MirvasO Soolantra Association In the Treatment of Moderate to Severe rosaCea.
The main objective of this study is to evaluate the efficacy of Ivermectin 1% cream (IVM) associated with Brimonidine 0.33% gel (Br) compared with the association of their respective vehicles in the treatment of moderate to…
- Trial name
- MOSAIC (NCT02616250)
- Testing
- Brimonidine 0.33% gel (Br), Ivermectin 1% cream (IVM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Galderma R&D
Rosacea
Analysis of the Microbiome in Rosacea
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy.
- Trial name
- NCT04108897
- Testing
- Doxycycline, Ivermectin Topical
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Papulopustular Rosacea
A Multicenter Trial of a Topical Medication for Papulopustular Rosacea Applied Twice Daily Versus Once Daily
To assess the efficacy and tolerability of azelaic acid 15% gel applied once daily versus twice daily in the treatment of patients with papulopustular rosacea.
- Trial name
- NCT00417937
- Testing
- azelaic acid 15% gel
- Where
- Germany
- Volunteers
- 98 people
- Sponsor
- LEO Pharma
Rosacea
A Study to Determine the Safety and Efficacy of Atralin (Tretinoin 0.05%) Gel for the Treatment of Rosacea
To compare the efficacy and safety of tretinoin gel 0.05% to its vehicle when dosed once or twice daily in female subjects with rosacea.
- Trial name
- NCT00621218
- Testing
- tretinoin gel 0.05%, vehicle
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Coria Laboratories, Ltd.
Rosacea
A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream"
A Randomized, Double-blind, Parallel-group, Three-arm, Placebo-controlled, Multi-Site Therapeutic Equivalence Study with Clinical End-points Comparing Test Product "Oxymetazoline hydrochloride Cream, 1%" to Reference Product…
- Trial name
- NCT03954444
- Testing
- Oxymetazoline Hydrochloride, Rhofade Cream, 1%
- Where
- United States
- Volunteers
- 1,105 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Rosacea
RosaC-RF : Bipolar Radiofrequency vs Doxycycline in Rosacea
Rosacea is a chronic facial disfiguring dermatosis characterized by different stages like flushing, erythema, telangiectasia and papulo-pustular lesions.
- Trial name
- Rosac-RF (NCT02204254)
- Testing
- Radiofrequence, Doxycycline
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Lipid Keratopathy, Penetrating Keratoplasty
Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal Neovasculization
1. Purpose:Our animal study demonstrated the effectiveness of subconjunctival injection of bevacizumab in the inhibition of corneal neovasculization formation.
- Conditions
- Lipid Keratopathy, Penetrating Keratoplasty, Herpetic Keratopathy, Rosacea
- Trial name
- NCT00681603
- Testing
- subconjunctival injection of bevacizumab ( 1.25 to 2.50 mg)
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
GVHD, Ocular Rosacea
IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD
The purpose of this study was to see if Intense Pulsed Light (IPL) can be used safely and effectively to help treat dry eyes from ocular rosacea after chronic graft-versus-host disease (GVHD).
- Conditions
- GVHD, Ocular Rosacea, Dry Eye Syndrome
- Trial name
- NCT02066051
- Testing
- IPL, Meibomian Gland Expression
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Demodicidosis, Rosacea
Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis
The purpose of this study is to determine whether 0.5% ivermectin cream is effective in the treatment of demodicidosis (including papulopustular rosacea)
- Trial name
- NCT02036229
- Testing
- ivermectin cream 0.5%
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Rosacea
Assessment of Rosacea Patients' Clinical Trial Experiences
Taking part in medical trials usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups.
- Trial name
- NCT05747391
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Rosacea
Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo
The purpose of this study is to assess relapse, efficacy and safety in subjects with rosacea during long-term treatment with either Oracea® or placebo, after an initial 12-week regimen of Oracea® and MetroGel® 1%.
- Trial name
- NCT01426269
- Testing
- Doxycycline, Metronidazole
- Where
- 11 sites in United States
- Volunteers
- 235 people
- Sponsor
- Galderma R&D
Papulopustular Rosacea
Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular Rosacea
Rosacea is a common chronic inflammatory relapsing-remitting skin condition almost exclusively affecting the central area of the face and the eyes.
- Trial name
- NCT05150587
- Testing
- Rifaximin
- Where
- 38 sites in United States
- Volunteers
- 216 people
- Sponsor
- Alfasigma S.p.A.
Facial Rosacea
Clinical Study of a Facial Cream for Rosacea
This study aimed to evaluate the efficacy, tolerability, and safety of Eucerin Skin Relief Multi-Repair Cream containing the active ingredient SenSiCel™ in improving facial rosacea.
- Trial name
- NCT07637032
- Testing
- ARM 1, ARM 2
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Rosacea
A Study of Laropiprant (MK-0524) in Participants With Moderate to Severe Erythematotelangiectatic Rosacea (MK-0524-155)
This study will assess the effect of MK-0524 relative to placebo, on signs and symptoms of rosacea and to determine the safety and tolerability profile of MK-0524 in participants with rosacea.
- Trial name
- NCT01451619
- Testing
- Laropiprant
- Volunteers
- 60 people
- Sponsor
- Merck Sharp & Dohme LLC
Rosacea Subtype 1 (Erythematotelangiectatic)
Efficacy and Tolerability of Topical Rossoseq™ Compared to Vehicle in Rosacea Subtype 1 (Erythematotelangiectatic)
Rossoseq™ is registered for the treatment of inflammatory skin conditions. Rosacea is one such inflammatory skin disorder that has not been studied yet for the use of Rossoseq™.
- Trial name
- NCT01666509
- Testing
- Rossoseq™
- Where
- 4 sites in Germany
- Volunteers
- 61 people
- Sponsor
- PBB Entrepreneur Ltd.
Acne, Actinic Keratosis
Potential Research Study Participant Registry
The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment.
- Conditions
- Acne, Actinic Keratosis, Dysplastic Nevi, Eczema
- Trial name
- NCT00710489
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Rosacea
Effects of Aminocaproic Acid (ACA) on Rosacea-specific Inflammation
The purpose of this study is to determine the effect of topical aminocaproic acid on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with rosacea.
- Trial name
- ACA (NCT01398280)
- Testing
- Topical aminocaproic acid (ACA) mixed with Vanicream, Vehicle cream
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego
Demodex Infestation, Rosacea
Facial Demodicosis and Ocular Demodicosis
To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of…
- Conditions
- Demodex Infestation, Rosacea, Blepharitis, Meibomian Gland Dysfunction
- Trial name
- NCT04377841
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Rosacea
A Study to Evaluate the Safety and Clinical Study of Azelaic Acid Gel 15% in Patients With Moderate Facial Rosacea
The purpose of the study is to compare the safety and efficacy profiles of a generic Azelaic Acid Gel, 15% to the reference listed Finacea® (azelaic acid) Gel, 15% in the treatment of moderate facial rosacea.
- Trial name
- NCT02120924
- Testing
- Azelaic acid, Vehicle, Finacea
- Where
- 30 sites in United States
- Volunteers
- 1,009 people
- Sponsor
- Actavis Inc.