Clinical trials: Rotator Cuff Repair
Rotator Cuff Tears
Biomarkers to Predict Rotator Cuff Repair Healing on Postoperative MRI
Rotator cuff repair healing is highly variable with healing failure rates ranging from 11 to 94%. To this date, there are no specific biomarkers in shoulder tissues that can be associated with rotator cuff healing after surgery.
- Trial name
- NCT07781553
- Testing
- MRN
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph W. Galvin
Rotator Cuff Tears
Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair
The purpose of this study is to see how well the ActiveMatrix® graft works at improving healing and function of the shoulder following rotator cuff repair surgery
- Trial name
- NCT05894265
- Testing
- ActiveMatrix® Dosage A, ActiveMatrix® Dosage B, Saline injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The University of Texas Health Science Center, Houston
Rotator Cuff Tears
The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair
The aim of the study is to evaluate the impact of cervical radiculopathy on functional status and quality of life outcomes in patients who have undergone rotator cuff repair, comparing the group with a history of cervical…
- Trial name
- NCT07001566
- Testing
- There was no intervention. Only assessment procedure will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Rotator Cuff Tear
Outcomes in Rotator Cuff Repair Using Graft Reinforcement
The purpose of this study is to evaluate patient shoulder functional outcomes following rotator cuff repairs reinforced with a surgical mesh.
- Trial name
- NCT01025037
- Testing
- Conexa Reconstructive Tissue Matrix
- Where
- 6 sites in United States
- Volunteers
- 61 people
- Sponsor
- Stryker Trauma and Extremities
Rotator Cuff Tear Repair
Evaluation of the Therapeutic Effect of Local Application of Tranexamic Acid in Rotator Cuff Repair
This prospective randomized controlled trial aims to evaluate the efficacy and safety of intraosseous tranexamic acid administration during arthroscopic rotator cuff repair.
- Trial name
- NCT07714473
- Testing
- Tranexamic Acid, Normal Saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Hua Luo
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Arthroscopic Rotator Cuff Repair
Comparison Between Abduction External Rotation Brace and Arm Sling After Arthroscopic Rotator Cuff
Comparison between Abduction External Rotation Brace and Arm Sling after Arthroscopic Rotator Cuff : A Randomized Controlled Trial Comparison of primary outcome : range of motion (at pre-operative , post-operative) , pain score …
- Trial name
- ARCR (NCT05948995)
- Testing
- Abduction external rotation brace
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
Shoulder Cuff Surgical Repair
Rotator Cuff Repair Under Isolated Loco-regional Anesthesia
Damage to the tendons of the shoulder, called rotator cuff, causes pain and loss of strength that may require surgery. This operation is performed under general anesthesia combined with loco-regional anesthesia of the shoulder.
- Trial name
- AGORA (NCT05848375)
- Testing
- Arthroscopic rotator cuff repair, naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA associated to GA), naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA)
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- Elsan
Rotator Cuff Tears, Rotator Cuff Injuries
Use of Nanoscaffold Augmentation in Rotator Cuff Repair: Clinical Outcome and Ultrasound Assessment of Healing Rates and Vascularity
The purpose is to assess Rotium, a novel nanoscaffold, impact on healing of a repaired rotator cuff and compare to a repair without Rotium.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Syndrome of Shoulder and Allied Disorders
- Trial name
- NCT04361266
- Testing
- Rotium nanoscaffold, Control arm rotator cuff repair
- Sponsor
- Joshua Szabo, MD
Rotator Cuff Tear, Tendon Injuries
Mesenchymal Stem Cells in Rotator Cuff Repair
Randomized clinical study involving 44 patients, evaluating the effect of mesenchymal cells on rotator cuff repair. The primary outcome will be post-operative MRI tendon integrity and secondary outcomes clinical assessment by the…
- Conditions
- Rotator Cuff Tear, Tendon Injuries, Mesenchymal Stem Cell
- Trial name
- NCT03362424
- Testing
- Mesenchymal stem cell, Rotator cuff repair
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Full Thickness Rotator Cuff Tear
BioFiber Scaffold Post-Market Observational Study
The aim of this study is to collect and report data from a consecutive series of patients implanted with these products as part of a post-market surveillance plan for CE Mark approval in the European Union.
- Trial name
- NCT01849458
- Testing
- BioFiber
- Where
- 3 sites in United States, France
- Volunteers
- 50 people
- Sponsor
- Stryker Trauma and Extremities
Rotator Cuff Tears
The Effect of Self-rehabilitation Using Communication APP After Arthroscopic Surgery for Rotator Cuff Tear
The purpose of this study was to assess the clinical effect of a mobile application supporting home-based rehabilitation for the patients after arthroscopic rotator cuff repair.
- Trial name
- NCT05102968
- Testing
- Home-based rehabilitation supporting with the mobile application, Supervised rehabilitation by the therapist
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Rotator Cuff Tear
Pilot Study of the Use of ULTRABRAID PLUS SUTURE in the Repair of Tears of the Rotator Cuff
The primary objective of this study is to obtain safety data on the use of the ULTRABRAID PLUS SUTURE, and to assess the preliminary effectiveness of the use of the ULTRABRAID PLUS SUTURE in comparison to the ULTRABRAID SUTURE in…
- Trial name
- NCT01767740
- Testing
- ULTRABRAID PLUS SUTURE, ULTRABRAID SUTURE
- Where
- 4 sites in Canada
- Volunteers
- 82 people
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff Tear Repair
Early Versus Delayed Postoperative Mobilization After Arthroscopic Rotator Cuff Tear Reapair.
Arthroscopic suture for complete and partial >50% thickness Rotator Cuff Tears (RCT) is the gold standard. However, there is no evidence of superiority of delayed postoperative mobilization protocols versus early ones, in terms…
- Trial name
- RAPIDREHAB (NCT04458025)
- Testing
- Standard rehabilitation program, Early rehabilitation program
- Sponsor
- Borja Alcobía-Díaz MD, PhD
Rotator Cuff Tears, Shoulder Pain
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
This study is a comparison of analgesia effect from peripheral nerve blockade (PNB) with liposomal bupivacaine combined with bupivacaine compared to PNB with ropivacaine combined with dexamethasone for arthroscopic rotator cuff…
- Trial name
- NCT04737980
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery Florida
Rotator Cuff Repairs, Pain Management
The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair
The goal of this clinical trial is to understand which group of pain control medications work best in adults after rotator cuff surgery.
- Trial name
- NCT07076069
- Testing
- Multimodal Pain Regimen, Standard of Care Pain Regimen
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Montefiore Medical Center
Rotator Cuff Tears of the Shoulder
Integrity Implant System Post Market Clinical Follow-Up Study
The study design is a prospective, multi-center, single-arm, non-randomized post market clinical follow-up study to confirm the performance, safety and clinical benefit of the Integrity Implant System when used for rotator cuff…
- Trial name
- NCT06741527
- Testing
- Integrity Implant System
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- Anika Therapeutics, Inc.
Rotator Cuff Injuries, Pain, Postoperative
Physical Therapy Interventions Following Arthroscopic Rotator Cuff Repair
In the post-arthroscopic rotator cuff repair (ARCR) management, physical therapy intervention is an important factor in bringing about a clinically positive prognosis.
- Conditions
- Rotator Cuff Injuries, Pain, Postoperative, Kinesiophobia
- Trial name
- NCT04711616
- Testing
- physical therapy intervention
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Sahmyook University
Arthroscopic Rotator Cuff Repair
Shoulder Anterior Capsular Block for Postoperative Analgesia in Arthroscopic Rotator Cuff Repair Surgery
Shoulder pain is frequently encountered in the medical field. Rotator cuff tears are the most common cause. Shoulder pain affects quality of life and delay rehabilitation programs.
- Trial name
- NCT06969625
- Testing
- (SHAC) block, (SSNB-ANB) block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University