Clinical trials: Rotator Cuff Repairs
Rotator Cuff Tear
Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery
This study is a randomized, double-blind, placebo-controlled pilot trial investigating the effects of BPC-157 on tendon healing and functional recovery following arthroscopic rotator cuff repair (aRCR).
- Trial name
- NCT07803250
- Testing
- BPC-157
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Rotator Cuff Tear
LifeNet: Extracellular Matrix Graft in Rotator Cuff Repair
This trial is to evaluate the effectiveness of the ArthroFLEX® ECM scaffold graph as an augment in rotator cuff repair surgery to reduce the failure rate of rotator cuff repairs for large and massive rotator cuff tears.
- Trial name
- NCT03551509
- Testing
- ArthroFLEX ECM scaffold graft, Control, Alternative Treatment Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Gregory Gilot
Rotator Cuff Tear
Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
Rotator cuff tears are seen in 40% of subjects over age 50 57, with a prevalence known to increase with each decade of life 51. Each year rotator cuff disorders lead to 4.5 million physician visits, 40,000 inpatient surgeries…
- Trial name
- NCT01383239
- Testing
- Immediate Postoperative Therapy, Delayed Physical Therapy
- Where
- 9 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Rotator Cuff Tear
Post-Op Rotator Cuff Pain Study With Subacromial Bupivacaine Infusion
Subacromial pain catheters have been used with uncertain efficacy for many years after rotator cuff repair to aid in postoperative pain control.
- Trial name
- NCT01126593
- Testing
- 0.5% bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Orlando Health, Inc.
Rotator Cuff Injury
Trial of the Use of Doxycycline After Rotator Cuff Repair
The purpose of this study is to examine healing after rotator cuff repair in subjects either treated with Doxycycline or placebo post-operatively.
- Trial name
- NCT02388477
- Testing
- Doxycycline, sugar pill
- Where
- United States
- Sponsor
- Milton S. Hershey Medical Center
Rotator Cuff Tear
A Safety Study Of BMP-655/ACS As An Adjuvant Therapy For Treatment Of Rotator Cuff Tears
Subjects undergoing an open surgical repair for their torn Rotator Cuff (RC) will be consented, screened, and enrolled in the study if they meet all eligibility criteria.
- Trial name
- NCT01122498
- Testing
- BMP-655/ACS+Standard of care or Standard of care
- Where
- 9 sites in Japan
- Volunteers
- 23 people
- Sponsor
- Pfizer
Rotator Cuff Tear, Rotator Cuff Injury
Rotator Cuff Tendon Repair With FiberLocker System Patch Augmentation
The overall objective of this clinical investigation is to assess the safety and efficacy of full-thickness arthroscopic rotator cuff repairs augmented with the FiberLocker System for the subjects.
- Conditions
- Rotator Cuff Tear, Rotator Cuff Injury, Rotator Cuff Rupture
- Trial name
- FIBERLOCK (NCT07005063)
- Testing
- FiberLocker® System (encompassing SpeedPatch® PET and FiberLocker Instrument® SN)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- ZuriMED Technologies AG
Pain
Pain Relief Following Arthroscopic Rotator Cuff Repair: Perioperative Pregabalin Administration Versus Interscalene Brachial Plexus Block
Arthroscopic rotator cuff (RC) repair is often associated with severe post operative pain and discomfort. Many analgesic protocols have been proposed for pain relief following RC repair and controversy remains regarding the…
- Trial name
- NCT01359085
- Testing
- Pregabalin, ISBPB - interscalene brachial plexus block
- Where
- Israel
- Volunteers
- 56 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Massive Rotator Cuff Tear
Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs
This prospective, single-arm interventional study will evaluate the effects of long head of the biceps tendon (LHBT) transposition without tenotomy as an augmentation technique for arthroscopic partial repair in adults with…
- Trial name
- ROTATORCUFF (NCT07375277)
- Testing
- LHBT Transposition Augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir Ataturk City Hospital
Rotator Cuff Tears
Tendon Transfer Rotator Cuff Tear
This is a prospective randomized study on using muscle tendons to repair tears of the muscles on the shoulder. There are 3 muscles covering the shoulder joint- supraspinatus, infraspinatus and subscapularis.
- Trial name
- NCT04588506
- Testing
- Lower Trapezius Tendon Transfer Technique, Latissimus Dorsi Tendon Transfer Technique, Pectoralis Tendon Transfer Technique
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Rotator Cuff Tear
A Comparison of Two Adjunctive Treatments in Arthroscopic Cuff Repair
This Clinical Trial is being conducted to study two adjunctive treatments for rotator cuff repair; soft tissue and bone trephination.
- Trial name
- NCT01706978
- Testing
- Bone Trephination, Soft Tissue Trephination
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tears, Postoperative Pain Management
Pain Education After Rotator Cuff Surgery
Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair Purpose: This study aims to…
- Conditions
- Rotator Cuff Tears, Postoperative Pain Management, Shoulder Dysfunction, Kinesiophobia (Fear of Movement)
- Trial name
- PNE-RCS (NCT06886932)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Elif Dilara Durmaz
Rotator Cuff Tear
Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
1. Treatment of rotator cuff tear The rotator cuff tear is the most demanding part of the shoulder surgery. Rotator cuff degeneration is thought to be the largest cause of rotator cuff tear.
- Trial name
- VITCRCR (NCT02992028)
- Testing
- Intravenous Nutrition (Vitamins) injection, Intravenous Saline injection
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Himchan Hospital
Shoulder Pain, Shoulder Injuries
MDR SureLock All-Suture Anchor
To report the outcomes of a series of patients with recurrent anterior and/or posterior shoulder instability who underwent surgical repair of the affected labrum using the SureLock all-suture anchor.
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Disease, Shoulder Pain Chronic
- Trial name
- NCT04093700
- Testing
- SureLock All-Suture Anchor
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Zimmer Biomet
Shoulder Arthroscopy, Soft Tissue Swelling
The Effect of Draping on Swelling in Shoulder Arthroscopy
Strategies to minimize soft tissue swelling during shoulder arthroscopy are constantly sought after. The investigators propose an unfamiliar method which may reduce tissue swelling during shoulder arthroscopy.
- Trial name
- NCT03216590
- Testing
- Compressive draping using adhesive incise drape
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Rotator Cuff Tears of the Shoulder
Acne Face Wash for Reducing the Contamination Rate in Arthroscopic Rotator Cuff Repair Surgery
Previous studies have shown that even when following standard sterilization protocols, the positive culture rate of Cutibacterium acnes can still be as high as 30%.
- Trial name
- NCT07239349
- Testing
- Acne face wash
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Rotator Cuff Injuries
TeleRehabilitation Following Arthroscopic Rotator Cuff Repair
Telerehabilitation is a form of tele-treatment in which rehabilitation services are dispensed at patients' home utilizing video telecommunication services with real-time synchronous exchange of information.
- Trial name
- NCT04541953
- Testing
- Telerehabilitation Therapy, In-person Rehabilitation Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Rotator Cuff Injuries
REGENETEN™ Bioinductive Implant System in Full-thickness Tears
The study is designed to assess the safety and efficacy of Arthroscopic rotator cuff repair (ARCR) augmented with REGENETEN in subjects requiring full-thickness rotator cuff tear repair or revision repair versus Arthroscopic…
- Trial name
- REGENETEN (NCT04450342)
- Testing
- Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery
- Where
- 30 sites in United States, Australia and 6 more
- Volunteers
- 119 people
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff Tear
An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS
The prognosis for patients with large rotator cuff tears is poor. This recently developed biologic scaffold provides numerous structural and functional properties that may direct cell growth and aid in tendon healing.
- Trial name
- NCT00182299
- Testing
- porcine small intestine submucosa (SIS)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Rotator Cuff Tear
Effect of Postoperative Immobilization on Healing After Rotator Cuff Arthroscopic Repair
The study aims to establish whether one month postoperative immobilization compared early passive motion after rotator cuff arthroscopic repair in small or medium ruptures with double row technique has any healing significance.
- Trial name
- NCT01502098
- Testing
- Postoperative early passive motion, Sling
- Where
- Argentina
- Volunteers
- 114 people
- Sponsor
- Hospital Italiano de Buenos Aires