Clinical trials: Roux-en-Y
Hypophosphatemia, Roux-en-Y Gastric Bypass
IV Iron-induced Hypophosphatemia After RYGB
The primary objective of the study is to compare the incidence of hypophosphatemia in RYGB patients treated with intravenous (IV) single dose of iron isomaltoside (Monofer®) or ferric carboxymaltose (Ferinject®).
- Trial name
- IVORY (NCT06350955)
- Testing
- Iron isomaltoside, Iron Carboxymaltose
- Where
- Switzerland
- Volunteers
- 94 people
- Sponsor
- Lucie Favre
Pancreatic Neoplasms, Bile Duct Neoplasms
Evaluation of Isolated Roux-en-Y Reconstruction After Pancreaticoduodenectomy
The purpose of this study is to evaluate the incidence of complications with the isolated Roux-en-Y reconstruction after pancreaticoduodenectomy in pancreatic tumor and periampullary tumor patients.
- Conditions
- Pancreatic Neoplasms, Bile Duct Neoplasms, Ampullary Neoplasms, Duodenal Neoplasms
- Trial name
- NCT00915863
- Testing
- Billroth-II-type reconstruction, Isolated Roux-en-Y type reconstruction
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Wakayama Medical University
Type 2 Diabetes Mellitus
The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass
The study is being undertaken to understand how a gastric bypass can affect a subject's diabetes even prior to their losing significant amounts of weight.
- Trial name
- NCT01843855
- Testing
- Exendin 9,39
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Adrian Vella
Pancreatoduodenectomy
Billroth II Versus Roux-en-Y for the Gastrojejunostomy in the Pancreatoduodenectomy
The purpose of this study is to compare the safety and superiority of Roux-Y versus Billroth II gastrojejunostomy reconstruction on delayed gastric emptying after pancreatoduodenectomy.
- Trial name
- NCT01984216
- Testing
- Roux-en-Y for the gastrojejunostomy reconstruction, Billroth II for the gastrojejunostomy reconstruction
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundacion Miguel Servet
Bariatric Surgery
Fat Absorption and Metabolism After Roux-en-Y Gastric Bypass
Using intravenous and oral administration of stable isotope tracers, we will investigate the importance of altered fat absorption and altered whole body fat metabolism for the reduced postprandial systemic TAG concentrations in…
- Trial name
- FAT-BAR (NCT04859816)
- Testing
- Metabolic test, DXA-scan, MRS
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Obesity
Metabolic Factors of Outcomes From Gastric Bypass Surgery
The objective of this study is to determine whether the metabolic, endocrine and energetic response to short term caloric restriction are factors in weight loss in subjects having gastric bypass (GB) surgery.
- Trial name
- Cassini (NCT01347840)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Ethicon Endo-Surgery
Obesity
Long-Term Follow-up of Ohio State University Medical Center (OSUMC) Bariatric Patients
Obtain long-term follow-up results for bariatric patients who underwent medical management or surgery for treatment of morbid obesity by Ohio State University Medical Center (OSUMC).
- Trial name
- NCT00700843
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ohio State University
Obesity, Metabolic Disease
Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery
The study aims to investigate whether tailoring limb lengths based on the 1/3rd and 2/3rd concept improves clinical outcomes in Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) surgery compared to conventional limb lengths.
- Conditions
- Obesity, Metabolic Disease, Bariatric Surgery Candidate, Metabolic Surgery
- Trial name
- TAILO-R-YGB (NCT06756789)
- Testing
- Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach, Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approach
- Where
- India
- Volunteers
- 40 people
- Sponsor
- GEM Hospital & Research Center
Morbid Obesity, Weight Loss
Intraoperative Measuring of Small Bowel Length Compared to Measuring by Magnetic Resonance Imaging (MRI) in Morbid Obese Patients
An important step during a gastric bypass operation for the treatment of morbid obesity is the measuring of the small bowel length.
- Trial name
- NCT00740662
- Testing
- Distal gastric bypass
- Where
- 2 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Complications, Operative Time
Eliminating Learning Curve Related Morbidity in Fast Track Laparoscopic Roux-en-Y Gastric Bypass
Background: Laparoscopic Roux en Y gastric bypass (LRYGB) is associated with a significant learning curve. We report the results of a systematic training programme from a high volume bariatric center measuring the outcome by…
- Conditions
- Postoperative Complications, Operative Time, Surgical Volume
- Trial name
- NCT01257789
- Testing
- laparoscopic gastric bypass
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Private Hospital Moelholm
Obesity, Morbid, Bariatric Surgery Candidate
Endoscopic Complications After Gastric Bypass
Endoscopic complications such as gastro-esophageal reflux disease, ulcera, gastritis, bile reflux, anastomotic stricture and so on are described after gastric bypass surgery.
- Trial name
- NCT03532646
- Testing
- upper endoscopy
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Sana Klinikum Offenbach
Stomach Neoplasms, Minimally Invasive Surgery
Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
To date, Roux-en-Y esophagojejunostomy transabdominal extracorporeally by circular stapler was the most common used method during laparoscopy-assisted total gastrectomy for gastric cancer, even though it was not totally…
- Conditions
- Stomach Neoplasms, Minimally Invasive Surgery, Anastomosis
- Trial name
- NCT02085031
- Testing
- Intracorporeal Roux-en-Y esophagojejunostomy, Extracorporeal Roux-en-Y esophagojejunostomy
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obesity, Morbid
Early Feasibility Study: Assessment of Self-Forming Magnetic Anastomosis Device and Delivery System (SFM) in Obese Patients, When Used to Create a Duodenal-Ileal Anastomosis Post SG (SNAP-PS), or Used to Create a Jejuno-Jejunal (J-J) Anastomosis
The objectives of this study are to assess the initial safety and device functionality of the SFM Anastomosis System including delivery systems when used to create a duodenal-ileal (D-I) anastomosis with patients with prior…
- Trial name
- GIW-J-J (NCT06200896)
- Testing
- Self Forming Magnets used to Create A Compression Anastomosis
- Where
- Chile
- Volunteers
- 28 people
- Sponsor
- GI Windows, Inc.
Roux-en-y Gastric Bypass, Post Prandial Hypoglycemia
Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.
The primary objective of this study is to assess the neuro-endocrine response to hypoglycaemia in PHH vs. non-PHH post-gastric bypass individuals.
- Trial name
- DEEP1B (NCT04334161)
- Testing
- Administration of glucose and controlled induction of hypoglycaemia.
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lia Bally
Type 2 Diabetes Mellitus, Obesity
Silastic Ring Gastric Bypass Versus Sleeve Gastrectomy for Type 2 Diabetes Mellitus in Obese Patients
Type 2 diabetes (T2DM) and obesity are becoming increasingly common in New Zealand (NZ) and worldwide. Both are associated with a risk of early mortality (death).
- Trial name
- NCT01486680
- Testing
- Laparoscopic Silastic Ring Roux-en-Y Gastric Bypass, Laparoscopic Sleeve gastrectomy
- Where
- 2 sites in New Zealand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- North Shore Hospital, New Zealand
Bariatric Surgery
Understanding Hypoglycaemia After Bariatric Surgery
Postprandial hyperinsulinaemic hypoglycaemia is an increasingly recognized adverse side effect of bariatric surgery. Affected individuals experience low glucose levels 1-3 hours after intake of meals, accompanied by symptoms such…
- Trial name
- HYPOBAR1 (NCT03609632)
- Testing
- Dietary Supplement: Glucose
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Post-bariatric Hypoglycaemia, Roux-en-Y Gastric Bypass
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 2
The overall aim of this study is to develop a sustainable hypoglycemia correction strategy.
- Trial name
- PBH Forecast (NCT05250271)
- Testing
- 15 g dextrose, 5 g dextrose, Protein bar
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Lia Bally
Non Alcoholic Steatohepatitis
Bariatric Surgery Versus Non-alcoholic Steato-hepatitis
Bariatric-metabolic surgery is effective in treating the cluster of conditions forming the metabolic syndrome, strictly associated with NAFLD and NASH.
- Trial name
- BRAVES (NCT03524365)
- Testing
- RYGB, SG, Intensive Lifestyle Modification
- Where
- 3 sites in Italy
- Volunteers
- 288 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity, Diabetes
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Biliopancreatic Diversion (BPD)- Duodenal Switch for Superobesity
The purpose of this study is to compare the outcome in a broad perspective after laparoscopic Roux-en-Y gastric bypass and laparoscopic BPD-duodenal switch in the treatment of superobesity (body mass index [BMI] > 50 kg/m2).
- Conditions
- Obesity, Diabetes, Hypertension
- Trial name
- ASGARD (NCT00327912)
- Testing
- Laparoscopic Biliopancreatic diversion with Duodenal switch, Laparoscopic Roux-en-Y Gastric Bypass
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Gastric Cancer
Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Health-Related Quality of Life in Patients Undergoing Total Gastrectomy for Adenocarcinoma
This study is being done to learn more about how different surgery procedures bring back the eating pathway after removing the stomach in patients with stomach cancer.
- Trial name
- NCT01491698
- Testing
- Roux-en-Y pouch reconstruction (RYP), conventional Roux-en-Y reconstruction (RYC)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center