Clinical trials: Roux-en-Y
Morbid Obesity
Long-term Adverse Effects After Bariatric Surgery on Oesophagus Epithelium
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on oesophageal symptoms and disease, including the presence of Barrett oesophagus ≥ 5 years post-surgery.
- Trial name
- FUB-B (NCT03410849)
- Testing
- Gastroscopy
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- University Hospital, Basel, Switzerland
Internal Hernia, Mesocolic Hernia
Internal Hernias After Laparoscopic Gastric Bypass
The main goal of this study is to describe the trends in the incidence rate of internal hernia presentation after different modifications of the mesenteric closure technique after primary laparoscopic Roux-en-Y gastric bypass…
- Conditions
- Internal Hernia, Mesocolic Hernia, Petersen´s Hernia, Jejunojejunostomy Hernia
- Trial name
- IHafterLRYGB (NCT01040364)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of California, San Francisco
Minimally Invasive Surgical Procedure, Laparoscopic Gastric Banding
Evaluation of Safety and Efficacy of the EndoLift Liver Retractor
The primary goal of the study is to evaluate the safety of the EndoLift Liver Retractor as an internal laparoscopic liver retraction device.
- Conditions
- Minimally Invasive Surgical Procedure, Laparoscopic Gastric Banding, Laparoscopic Roux-en-Y Gastric Bypass, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT02008409
- Testing
- EndoLift Liver Retractor
- Where
- United States
- Sponsor
- Duke University
Obesity
Effects of Roux-en-Y Gastric Bypass on Gastro-intestinal Hormone Secretion and Brain Responses Food Pictures
This is a cross-sectional study enrolling 11 weight-stable, formerly obese female patients 1-5 years after Roux-en-Y gastric Bypass (RYGB) 11 age- and weight-matched female subjects 10 normal weight (Body Mass Index 19-25 kg/m2)…
- Trial name
- NCT02160379
- Testing
- standard test meal
- Where
- Switzerland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Severe Obesity
Sleeve Gastrectomy With Transit Bipartition(SG+TB) Versus Roux-en-Y Gastric Bypass (RYGB) for Type 3 Obesity
Obesity is a major public health problem worldwide. Bariatric surgery has proved to be the most effective treatment of morbid obesity in terms of weight reduction and remission of co-morbid conditions during long-term follow-up.
- Trial name
- BIPASS (NCT04915014)
- Testing
- sleeve gastrectomy with transit bipartition (SG +TB), Roux-en-Y gastric bypass (RYGB)
- Where
- 8 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Lille
Hypoglycemia
The Effect of Glucomannan Soluble Fiber on Glucose Homeostasis in Patients With Roux En Y (RNY) Gastric Bypass Surgery
One of the emerging complications of RNY gastric bypass surgery is mild to severe refractory/ recurrent postprandial hypoglycemia. This complication can lead to a significant reduction in quality of life to severe disability.
- Trial name
- NCT02336438
- Testing
- glucomannan
- Volunteers
- 10 people
- Sponsor
- Bassett Healthcare
Pancreatic Cancer
A Comparative Clinical Research on Single Roux-en-Y and Traditional Roux-en-Y of Pancreaticojejunostomy-choledochojejunostomy For Treatment of Obstruction of Pancreatic Duct and Bile Duct
This study is being done to learn more about how different surgery procedures bring back the quality of life.After removing the small intestine at least 20cm in patients with pancreatic cancer, Some patients develop problems…
- Trial name
- NCT01926717
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengyi Sun
Obesity and Overweight, Bariatric Surgery (Gastric Bypass)
Protein Requirements After Bariatric Surgery
The study investigates protein requirements at least 1 year after gastric bypass surgery in adult males, to investigate whether protein requirements are elevated compared to protein requiremens for the general populaiotn.
- Conditions
- Obesity and Overweight, Bariatric Surgery (Gastric Bypass), Protein Requirement
- Trial name
- PROXY (NCT06853652)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastric Tumor
Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Quality of Life in Patients Undergoing Total Gastrectomy
The purpose of this study is to find out more about differences of the quality of life in patients undergoing Roux-En-Y pouch reconstruction and conventional Roux-En-Y reconstruction.
- Trial name
- GCQOL02 (NCT01697943)
- Testing
- Roux-En-Y Pouch Reconstruction or Conventional Roux-En-Y Reconstruction
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fudan University
Obesity, Diabetes Mellitus, Type 2
Bariatric Surgery and Male Reproductive Function
Obesity is a global public health problem. According to literature reports, as of 2016, China's obese population has reached more than 90 million and type 2 diabetes mellitus has reached more than 100 million, which has brought a…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Bariatric Surgery Candidate, Roux en Y Gastric Bypass
- Trial name
- NCT04237311
- Testing
- Sleeve gastrectomy, Roux-en-Y gastric bypass
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Gastric Emptying, Roux-en-Y Gastric Bypass
Bariatric Procedures and Changes Gastric Passage
Gastric emptying measured with scintigraphy in patients after standard Roux-en-Y Gastric Bypass (S-RYGB), Banded-RYGB (B-RYGB) or Extended pouch-RYGB (E-RYGB).
- Conditions
- Gastric Emptying, Roux-en-Y Gastric Bypass, Bariatric Surgery
- Trial name
- BIP (NCT04972357)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Rijnstate Hospital
Obesity, Roux-en-y Anastomosis Site
Comparing Reduction With ESD- Versus APC-TORe
The goal of this clinical trial is to compare two variations of the same procedure used to assist with weight loss in patients who have a history of Roux-en-Y gastric bypass who have experienced weight regain.
- Conditions
- Obesity, Roux-en-y Anastomosis Site, Weight Gain
- Trial name
- CREATORe (NCT06131281)
- Testing
- E-TORe, c-TORe
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stephen Firkins
Obesity, Roux-en-Y Gastric Bypass
A Registry of Laparoscopic Bariatric Surgery Using Stapling Devices: Observation of Safety and Clinical Efficacy
The purpose of this observational registry is to evaluate the safety and the clinical efficacy of laparoscopic bariatric surgery using stapling devices (easyEndoTM Universal Linear Cutting Stapler and reloads from Ezisurg…
- Conditions
- Obesity, Roux-en-Y Gastric Bypass, Gastrostomy, Nissen Sleeve
- Trial name
- STAP-JOLI (NCT04808206)
- Testing
- easyEndoTM Universal Linear Cutting Stapler and reloads (Ezisurg Medical)
- Where
- 3 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- Duomed
Type 2 Diabetes, Morbid Obesity
Type 2 Diabetes After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: A Randomised Single Centre Study
Glycaemia, insulin secretion and action in morbidly obes subjects with type 2 diabetes after sleeve gastrectomy ond Roux-en-Y gastric bypass: A randomised single centre study.
- Trial name
- OSEBERG (NCT01778738)
- Testing
- Bariatric surgery, either gastric bypass surgery or sleeve gastrectomy, Sleeve gastrecomy, Bastric bypass
- Where
- Norway
- Volunteers
- 125 people
- Sponsor
- Sykehuset i Vestfold HF
Obesity, Morbid, Overnutrition
Comparative Analysis Between Sleeve Gastrectomy and Roux-en Y Gastric Bypass in Bariatric Operation
Prospective, double-arm, multi-center cohort study on obese patients, for laparoscopic sleeve gastrectomy versus Roux-en Y gastric bypass
- Conditions
- Obesity, Morbid, Overnutrition, Nutrition Disorders, Overweight and Obesity
- Trial name
- NCT04554758
- Testing
- Sleeve gastrectomy, Roux-en-Y gastric bypass
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Inha University Hospital
Benchmark, Bariatric Surgery
Defining Benchmarks in Bariatric Surgery
Aim: To define benchmark outcomes in minimally-invasive primary bariatric surgery. Design: Multicenter retrospective cohort study.
- Conditions
- Benchmark, Bariatric Surgery, Roux-en-y Gastric Bypass, Sleeve Gastrectomy
- Trial name
- BBenchmarks (NCT03440138)
- Testing
- bariatric surgery (RYGB or SG)
- Where
- Switzerland
- Volunteers
- 5,741 people
- Sponsor
- Marco Bueter
Obesity, Morbid, Bariatric Surgery
Photographic Food Recognition and Meal Size Estimation Before and After Roux-en-Y Gastric Bypass
Direct measurements of changes in food selection in humans after RYGB have been limited by the unreliability of patients, which poses significant methodological and conceptual challenges to researchers and study design.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Roux-en-Y Gastric Bypass, Food Preferences
- Trial name
- NCT04600596
- Testing
- Recording of food intake.
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marco Bueter
Weight Loss
Impact of Biliopancreatic Limb Lenght on Long-term Weight Loss After Roux-en-Y Gastric Bypass
Patients were randomly assigned into 2 groups: those patients undergoing RYGB with a BPL of 70cm and those ones undergoing RYGB with a BPL of 120 cm. Excess BMI loss 5 years after surgery was investigated
- Trial name
- NCT03607305
- Testing
- BP limb 70cm, BP limb 120cm
- Volunteers
- 506 people
- Sponsor
- Hospital General Universitario Elche
Diabetes Mellitus Type 2 in Nonobese, Gastric Cancer
Safety and Efficacy of Long Limb Roux-en Y Reconstruction
We grafted the concept of metabolic surgery (long limb Roux-en Y reconstruction) into gastric cancer surgery. This study aimed to investigate the safety and efficacy of long limb Roux-en Y reconstruction after gastrectomy in…
- Trial name
- LoLiRoRe (NCT01373346)
- Testing
- Long limb Roux-en Y reconstruction
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Gangnam Severance Hospital
Bariatric Surgery (Gastric Bypass), Severe Obesity
Gut Hormones as Mediators of Different Weight Loss Responses After Roux-en-Y Gastric Bypass
After gastric bypass, 10-20% of patients will obtain a suboptimal weight loss, often defined as <50% of the excess body weight. Exaggerated meal related secretion of gut hormones seem important for appetite reduction and…
- Trial name
- NCT02374632
- Testing
- Meal tests after saline injection, Meal tests after octreotide injection
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital