Clinical trials: Rumination Disorders, open to volunteers
Anxiety, Anxiety Depression
Calming Minds Study
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1.
- Conditions
- Anxiety, Anxiety Depression, Worry, Depression
- Trial name
- NCT07577401
- Testing
- Be Specific, Be Kind, Be Present
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, Los Angeles
Distress, Emotional, Emotional Dysfunction
Brief Interventions for Coping with Distress
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training…
- Conditions
- Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
- Trial name
- NCT05779761
- Testing
- Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Teachers College, Columbia University
Feeding and Eating Disorders
Metacognitive Beliefs in Adolescents With Eating and Nutrition Disorders
The present study aims to study the presence of metacognitive beliefs in adolescent subjects with eating and nutrition disorders (END) compared with a control group composed of subjects of the same sex and age belonging to the…
- Trial name
- METAED (NCT06800807)
- Testing
- Observation of several factors involved in eating and nutrition disorders
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Istituto Auxologico Italiano
Rumination
Effect of Environment on the Central and Peripheral Nervous System
The main goal of this study is to understand how different environments influence both mental responses, like overthinking (rumination), and physical reactions, such as heart rate and blood pressure, after a challenging task.
- Trial name
- RUMI (NCT06778356)
- Testing
- Built environment, Natural environment
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Rumination Syndrome
Treatment of Rumination
Background: Rumination syndrome is characterized by the involuntary regurgitation of previously ingested food from the stomach to the mouth, triggered by an unintentional contraction of the abdominal muscles along with…
- Trial name
- NCT06971354
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Suicidal Ideation Active, Depression Disorders
Personalized TACS to Reduce Rumination in Patients with Active Suicidal Ideation
The goal of this clinical trial is to determine whether modulating default mode network (DMN) alpha connectivity using transcranial alternating current stimulation (tACS) can reduce rumination and, in turn, mitigate feelings of…
- Trial name
- Alpha-MOD (NCT06832124)
- Testing
- alpha-tACS
- Volunteers
- 50 people
- Sponsor
- Sebastian Olbrich
Depression, Treatment Resistant
rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression
The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in adults with major depression…
- Trial name
- NCT06511544
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Barrett Esophagus, Anorexia Nervosa, Binge Eating/Purging Type
Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype
To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors
- Conditions
- Barrett Esophagus, Anorexia Nervosa, Binge Eating/Purging Type, Rumination, Vomiting
- Trial name
- NCT06532734
- Testing
- EsoGuard
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Denver Health and Hospital Authority
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Rumination, Major Depressive Disorder
Decoding and Modulating Affective Brain States
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS).
- Conditions
- Rumination, Major Depressive Disorder, Anxiety
- Trial name
- NCT05437705
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Major Depressive Disorder, Mood Disorders
Mechanisms of Rumination Change in Adolescent Depression
This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with…
- Trial name
- RuMeChange (NCT03859297)
- Testing
- Rumination-Focused CBT, Relaxation-based Therapy
- Where
- 3 sites in United States
- Volunteers
- 183 people
- Sponsor
- Ohio State University
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Insomnia, Depression
Sleep to Reduce Incident Depression Effectively in Peripartum
Perinatal depression (PND) is the most common complication in pregnancy and postpartum, which increases risk for adverse perinatal outcomes such as preterm birth, maternal suicidal thoughts, and impaired mother-infant bonding.
- Trial name
- STRIDE P (NCT06430333)
- Testing
- Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Henry Ford Health System
Bipolar Disorder I or II
A Compassionate-focused Intervention for Older People with Bipolar Disorder
The aim of this study is to determine whether it is feasible to deliver a 9-session compassionate-focused therapy for older people with bipolar disorder.
- Trial name
- NCT06882590
- Testing
- Compassionate-focused therapy
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Manchester
Cognitive Flexibility, Rumination
The Effect of Cognitive Behavioral Therapy (CBT)-Based Psychoeducation on Cognitive Flexibility and Rumination in the Elderly
This study aimed to investigate the effect of psychoeducation on rumination and cognitive flexibility in elderly individuals residing in nursing homes.
- Conditions
- Cognitive Flexibility, Rumination, Elderly (People Aged 65 or More), Psychoeducation
- Trial name
- NCT07139197
- Testing
- Cognitive Behavioral Approach-Based Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ataturk University
Stress and Memory in Adolescence
My Life and My Experiences Project
Child maltreatment is one of the most formidable public health crises in the United States, affecting millions of youth each year.
- Trial name
- M&M Project (NCT06821178)
- Testing
- Acute stress manipulation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Substance Use Disorder (SUD), Addiction
NLP Analysis of Weekly Narratives for Dynamic Clinical Assessment in SUD
This prospective observational study follows adults undergoing residential rehabilitation for severe substance use disorders at a specialized treatment center in Mexico.
- Conditions
- Substance Use Disorder (SUD), Addiction, Anxiety, Emotional Dysregulation
- Trial name
- DYNA-NLP (NCT07595614)
- Testing
- Residential rehabilitation as usual
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Lauro Gutiérrez Castro
Depression - Major Depressive Disorder, Depression Disorders
Meditative Neurofeedback for Depression
The goal of this study is to test a meditative neurofeedback intervention for depressed mood.
- Trial name
- MediNF (NCT06675240)
- Testing
- MediNF
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Generalized Anxiety, Fear of Failure
Optimization of Late Imagery Rescripting Research Using Generative Artificial Intelligence
The aim of the study is to examine the effect of imagery rescripting (ImRs) in the context of utilizing large language models (LLMs).
- Conditions
- Generalized Anxiety, Fear of Failure, Rumination
- Trial name
- ImRs_LLM_DeanG (NCT07565714)
- Testing
- Imagery Rescripting Intervention
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Obesity
Metacognitive Beliefs in Obese Patients
The study aims to investigate the presence of metacognitive beliefs, emotional regulation, and emotional eating in obese patients and their possible relationships.
- Trial name
- METAOBES (NCT06800911)
- Testing
- Questionnaires
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituto Auxologico Italiano