Clinical trials: Rupture of the Rotator Cuff
Rotator Cuff Tears
Platelet Rich Plasma on Rotator Cuff Repair
Repair of the rotator cuff has high rates of re-rupture (20-54%), despite good clinical results. Several ways to improve the healing tendon-bone are currently studied, among them the most used is the use of growth factors.
- Trial name
- PRP (NCT01029574)
- Testing
- Platelet rich plasma
- Where
- 2 sites in Brazil
- Volunteers
- 54 people
- Sponsor
- University of Sao Paulo
Rotator Cuff
The Research About the Function of the Rotator Cuff After Humeral Greater Tuberosity Fractures
The purpose of this retrospective study was to investigate the differences in fracture block and rotator cuff function in patients with rotator cuff injuries due to greater tuberosity humerus fractures.
- Trial name
- NCT07368725
- Testing
- without intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guo Jialiang
Rotator Cuff Tear
An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS
The prognosis for patients with large rotator cuff tears is poor. This recently developed biologic scaffold provides numerous structural and functional properties that may direct cell growth and aid in tendon healing.
- Trial name
- NCT00182299
- Testing
- porcine small intestine submucosa (SIS)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Rotator Cuff Injuries, Kinesiophobia
The Effect of Pain Neuroscience Education on Patients With Arthroscopic Rotator Cuff Repair
During the rehabilitation process after rotator cuff repair surgery, patients suffer from increased pain and discomfort due to dysfunction.
- Conditions
- Rotator Cuff Injuries, Kinesiophobia, Pain, Postoperative
- Trial name
- NCT04705311
- Testing
- Pain neuroscience education, Rotator cuff repair rehabilitation
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Sahmyook University
Partial Thickness Supraspinatus Tendon Tear, Full Thickness Supraspinatus Tendon Tear
Post-Market Evaluation of the Rotation Medical Rotator Cuff System
The purpose of this study is to evaluate bioinduction of new tissue and tendon healing after implantation of the Rotation Medical Bioinductive Implant used as either a standalone device or adjunct to surgical repair in the…
- Trial name
- NCT02200939
- Testing
- Bioinductive implant, Surgical repair
- Where
- 15 sites in United States
- Volunteers
- 148 people
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Cellular Content of Bone Marrow Aspiration, Comparison
The goal of this observational clinical trial is to determine whether the posterior superior iliac spine of the hip or the humerus of the arm will produce larger amounts of bone marrow when harvested during surgery.
- Trial name
- BioCuff (NCT05573347)
- Testing
- Rotator Cuff Repair, Bone Marrow Harvest
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Andrews Research & Education Foundation
Rotator Cuff Tears, Rotator Cuff Injuries
Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study)
Treatment of rotator cuff tears with micro-fragmented adipose tissue is a minimal-invasive procedure with the potential to shorten and ease recovery, accelerate return to daily activity and work of thus with a potential capacity…
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Tear Arthropathy
- Trial name
- NCT06505135
- Testing
- Stem-cell treatment, Standard care
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Rotator Cuff Tear
InSpace™ System Implantation in a Procedure Under Local Anesthesia
The study objective is to assess the feasibility, efficacy and safety of the InSpace™ Device implantation in a surgical procedure under local anesthesia using arthroscopic and/or fluoroscopic visualization of the affected…
- Trial name
- NCT02208453
- Testing
- InSpace Implantation
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- OrthoSpace Ltd.
Supraspinatus Tear
Treatment of the Biceps With Concomitant Supraspinatus Tears
The long head of the biceps (LHB) tendon is thought to be a common source of shoulder pain and dysfunction in patients with rotator cuff pathology.
- Trial name
- NCT05660031
- Testing
- LHB Tenotomy, LHB Tenodesis
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 180 people
- Sponsor
- La Tour Hospital
Rotator Cuff Tears, Micro Fracture
Microfracture at Proximal Humerus Lateral to Footprint Could Enhance the Rotator Cuff Healing
The goal of this clinical trial is to test whether there is any effect on rotator cuff healing by making microfracture at the lateral side of the footprint.
- Trial name
- NCT05624164
- Testing
- Lateralised microfracture
- Where
- 2 sites in China
- Volunteers
- 88 people
- Sponsor
- Affiliated Hospital of Nantong University
Calcifying Tendinitis of Shoulder
Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection
Calcific tendinitis of the rotator cuff is a common cause of chronic pain of the shoulder. Needling and lavage of the calcification is one of the therapeutic options after failure of conservative management with physiotherapy and…
- Trial name
- CALCECHO (NCT02403856)
- Testing
- Sodium Chloride 0.9%, Methylprednisolone acetate, Ultrasound-guided Needling and Lavage
- Where
- 3 sites in France
- Volunteers
- 136 people
- Sponsor
- Nantes University Hospital
Rotator Cuff Tendonitis, Bicipital Tendonitis
Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area.
- Conditions
- Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder
- Trial name
- NCT00640939
- Testing
- diclofenac sodium
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Cerimon Pharmaceuticals
Rotator Cuff Injuries
The Effects of Yoga on Patients With Rotator Cuff Injuries
To determine if patients who undergo a 6-week online yoga exercise treatment differ from those who undergo a 6-week online standard exercise intervention and patients who do not undergo any treatment (the control).
- Trial name
- NCT02528084
- Testing
- yoga, standard exercises
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rotator Cuff Tears
Biomarkers for the Surgical Treatment of Rotator Cuff Tears
Identification of biomarkers that can predict the outcome of the surgical treatment (i.e. the rate of re-rupture) of tears in the rotator cuff tendon.
- Trial name
- MARK-GEROT (NCT02123784)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Balgrist University Hospital
Rotator Cuff Impingement Syndrome, Rotator Cuff Injury
The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain
Background: Despite similar treatment outcomes for surgery or conservative care, the number of surgeries for the care of rotator cuff (RTC) related shoulder pain has increased.
- Conditions
- Rotator Cuff Impingement Syndrome, Rotator Cuff Injury, Shoulder Pain
- Trial name
- NCT03353272
- Testing
- Patient Engagement Education and Restructuring of Cognitions
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Duke University
Rotator Cuff Tear Arthropathy
Immobilization in Reverse Shoulder Prosthesis
Reverse shoulder prostheses are the treatment of choice in elderly patients with rotator cuff arthropathy. Traditionally these patients have been immobilized for 3 weeks in the immediate postoperative period in order to have good…
- Trial name
- NCT04645329
- Testing
- shoulder immovilization sling
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital del Mar
Rotator Cuff Injuries
Telerehabilitation for Shoulder Surgery Recovery
This study aims to evaluate the effectiveness of a telerehabilitation protocol utilizing the Band Connect platform in patient recovery following rotator cuff repair surgery.
- Trial name
- NCT07392502
- Testing
- Band Connect, Physical Therapy
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- NYU Langone Health
Rotator Cuff Tears
Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
Phase I/II, multi-center, prospective, blinded 2arm, parallel design and randomized controlled study. Assessing the Ortho-R/PRP combination and standard of care for rotator cuff repair, will be compared though 12 months.
- Trial name
- NCT05333211
- Testing
- Ortho-R/PRP
- Where
- 9 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- ChitogenX Inc
Bankart Lesions, SLAP Lesion
PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder
The study is a multicenter, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to collect data confirming safety, performance and clinical benefits of the…
- Conditions
- Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction
- Trial name
- NCT05584553
- Testing
- ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
- Where
- 3 sites in United States, Spain
- Volunteers
- 214 people
- Sponsor
- Zimmer Biomet
Shoulder Pain, Rotator Cuff Injuries
Shoulder RFA Pilot Study
Through this prospective, single-arm cohort pilot study, we plan to explore the safety and effectiveness of Shoulder Radiofrequency Ablation (SRFA) in patients with non-operative chronic shoulder pain due to shoulder…
- Trial name
- NCT06039345
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Utah