Clinical trials: Ruptured Aneurysm
Aneurysm Abdominal, Cerebral Aneurysm Ruptured
Occurrence of Abdominal Aortic Aneurysms in Patients With Aneurysmal Subarachnoid Hemorrhage
Rationale: Aneurysms of different types are known to be associated. In literature, concurrence of intracranial- and aortic aneurysms is described.
- Trial name
- TRACE-aSAH (NCT07312565)
- Where
- Netherlands
- Volunteers
- 233 people
- Sponsor
- Leiden University Medical Center
Intracranial Aneurysm, Stent Embolisation
Treatment of Unruptured Intracranial Aneurysms in China
Un-ruptured intracranial aneurysm is a complex disease that seriously affects human life and health. At present, the treatment of intracranial aneurysm is divided into interventional treatment and craniotomy clipping, the two…
- Conditions
- Intracranial Aneurysm, Stent Embolisation, Craniotomy, Coil-assissted Embolisation
- Trial name
- NCT03133598
- Where
- China
- Volunteers
- 5,126 people
- Sponsor
- Zhujiang Hospital
Intracranial Aneurysm
Enterprise Stent Aneurysm Treatment (ESAT) Study - France
The purpose of this study is to evaluate the morbidity, mortality, and efficacy of use of the Enterprise(TM) stent for the treatment of (ruptured or non-ruptured) intracranial aneurysms.
- Trial name
- ESAT (NCT00879580)
- Where
- 14 sites in France
- Volunteers
- 133 people
- Sponsor
- Codman & Shurtleff
Intracranial Aneurysms, Ruptured Aneurysm
Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN
Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location.
- Trial name
- PLAQRAN (NCT03408379)
- Testing
- Collection of blood sample in aneurysm
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Aneurysm, Ruptured, Aneurysmal Subarachnoid Hemorrhage
Brain Imaging After Non-traumatic Intracranial Hemorrhage (SAVEBRAINPWI)
The study is an observational prospective evaluation of an approved and unchanged clinical management, evaluating different diagnosis methods to assess brain perfusion in patients with an aneurysmal or AVM-related intracranial…
- Conditions
- Aneurysm, Ruptured, Aneurysmal Subarachnoid Hemorrhage, Arteriovenous Malformations, Intracranial Aneurysm
- Trial name
- SAVEBRAINPWI (NCT05276934)
- Testing
- Brain computed tomography
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Aneurysm, Ruptured, Vasospasm, Intracranial
Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)
Previous work has demonstrated patients presenting with ruptured aneurysms that develop radiographic and clinical vasospasm have a higher permeability of the blood brain membrane.
- Conditions
- Aneurysm, Ruptured, Vasospasm, Intracranial, Delayed Cerebral Ischemia, Blood Brain Barrier Defect
- Trial name
- NCT04876638
- Testing
- Minocyclin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit
The goal of this observational study is to investigate DNA methylation changes in adults with bleeding from brain aneurysm, which is called aneurysmal subarachnoid hemorrhage (aSAH), and their association with delayed ischemic…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm After Subarachnoid Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT06881329
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Brain Aneurysm, Aneurysm, Ruptured
Superior Cervical Ganglion Block, Transcranial Doppler
The aim of this study is to assess blood flow velocity in middle cerebral artery measured by transcranial doppler to determine the efficacy of SCG block in decreasing incidence or severity of vasospasm after MCA aneurysm surgery.
- Trial name
- NCT04439760
- Testing
- Superior Cervical Ganglion Block
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Fatma Ibrahim El Sayed Salman
Abdominal Aortic Aneurysm
Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic Aneurysm
Preconditioning in patients treated for elective abdominal aneurysm showed that the rate of perioperative myocardial infarction could be reduced by 80 %(ARR from 27% to 5%).
- Trial name
- PreconRAAA (NCT00883363)
- Testing
- Precondition
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Nikolaj Eldrup
Thoracic Aorta
Aortic Elongation and Dissection
Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.
- Trial name
- NCT02722889
- Where
- Netherlands
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Intracranial Hemorrhage Ruptured Aneurysm
International Subarachnoid Aneurysm Trial II
The purpose of this study is to compare the clinical outcome of surgical clipping and endovascular coiling for ruptured intracranial aneurysms not included in the original ISAT Study.
- Trial name
- ISATII (NCT01668563)
- Testing
- surgical management, Endovascular management
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 1,724 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Intracranial Aneurysm, Anterior Communicating Artery Aneurysm
Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy
Based on the anatomical features of the anterior Communicating artery complex, the investigators will analyze the outcome of the ACoA aneurysms treated by endovascular therapy.
- Conditions
- Intracranial Aneurysm, Anterior Communicating Artery Aneurysm, Cerebral Aneurysm, Aneurysm, Ruptured
- Trial name
- MACAARET (NCT02444832)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Clinic of Barcelona
Aneurysms Saccular, Aneurysm, Ruptured
Pre-SEAL™IT: Saccular Endovascular Aneurysm Lattice System First In Human Interventional Trial
To establish the preliminary safety and effectiveness of the SEAL™ Endovascular Aneurysm Lattice System for the treatment of saccular intracranial aneurysms. The data from this study will be used to support: 1.
- Conditions
- Aneurysms Saccular, Aneurysm, Ruptured, Aneurysm
- Trial name
- Pre-SEAL™IT (NCT05686733)
- Testing
- SEAL Device
- Where
- Colombia
- Volunteers
- 26 people
- Sponsor
- Galaxy Therapeutics INC
Intracranial Aneurysm, Stroke, Ischemic
Neurovascular Product Surveillance Registry
Post market surveillance registry
- Trial name
- INSPIRE (NCT02988128)
- Testing
- Treatment for intracranial aneurysms, Treatment for Acute Ischemic Stroke
- Where
- 99 sites in Argentina, Australia and 22 more
- Volunteers
- 4,000 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurysm, Ruptured, Intracranial Aneurysm
Bare Platinum Coils Versus Second-generation Hydrocoils
Comparison of clinical and radiological outcomes between bare platinum coil group and second-generation hydrogel coils for treatment of ruptured intracranial aneurysms.
- Trial name
- NCT04988503
- Testing
- Coil embolization
- Where
- 3 sites in South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Intracranial Aneurysm, Ruptured Aneurysm
EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)
The purpose of the study is to assess the safety and effectiveness of the Pipeline™ Flex Embolization Device with Shield Technology™ in the treatment with acutely ruptured intracranial aneurysms.
- Trial name
- ELEVATE (NCT04391803)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Turner Syndrome
Aortic Dimensions in Turner Syndrome
An observational study of 102 women with Turner syndrome followed for 6 years with a two-yearly examination including ECHO, MRI of the heart and 24 ambulatory blood pressure.
- Trial name
- NCT00624949
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Aortic Rupture
Prediction of Aortic Dilatation and Rupture
Aortic aneurysm is a very common incidental finding in the diagnostic imaging of the chest. It is especially common in middle aged men (up to 40 %).
- Trial name
- DilAo (NCT05065996)
- Testing
- Aortic MRI + 4D flow MRI
- Where
- Finland
- Volunteers
- 170 people
- Sponsor
- Kuopio University Hospital
Printing, Three-Dimensional, Simulation Training
Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms
Cerebral aneurysm is one of the main diseases that seriously affect human health. The most important treatment method is surgical clipping and endovascular embolization.
- Trial name
- PAOCA (NCT02977520)
- Testing
- Printing, Three-Dimensional
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Luhe Hospital
Cerebral Aneurysm Unruptured, Cerebral Aneurysm Ruptured
Surgical Theater's Surgery Rehearsal Platform
Objectives: The objective of this clinical study is to determine if the use of the SRP will lead to improved effort and time efficiency in cerebral aneurysm surgery.
- Trial name
- SRP (NCT02099318)
- Testing
- Active SRP cases, Control cases
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center