Clinical trials: S100A8
Peri-Implantitis, Dental Implant Failed
Assessment of Efficacy of Calprotectin and Cross-linked N-telopeptides
The study aims to assess the efficacy of Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid as a biomarker in patients with peri-implantitis.
- Trial name
- NCT04177732
- Testing
- Collection of sulcular (crevicular) fluid, Probing depth, Bleeding on probing
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansour Assery
Enteropathy, Necrotizing Enterocolitis
Use of Faecal Calprotectin to Predict Enteropathy of the Preterm Neonates
This study aims to evaluate a clinico-biological predictive score, associating the faecal calprotectin, for the diagnosis of enterocolitis and enteropathy of the preterm neonates.
- Trial name
- CALPROPREMA (NCT02010268)
- Testing
- Collection of stool samples
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Moderate to Severe Ulcerative Colitis
Fecal Calprotectin Levels, Quality of Life, and Workability in Patients Suffering From Ulcerative Colitis Under Adalimumab Therapy - AdaProQuo
The objectives of this study are to explore the fecal calprotectin (fC) levels of UC patients under adalimumab therapy and the correlation with their general wellbeing (Quality of Life [QoL]), workability, and disease activity.
- Trial name
- AdaProQuo (NCT02092389)
- Volunteers
- 10 people
- Sponsor
- AbbVie
Peptic Esophagitis, Peptic Ulcer
Diagnostic Value of Fecal Calprotectin in Disorders of the Upper Gastrointestinal Tract
Fecal calprotectin is a very sensitive non-invasive inflammation marker in the detection of inflammatory bowel disease and, to a lesser degree, has also proven to be useful in adenomatous polyps, neoplasias, and infectious…
- Conditions
- Peptic Esophagitis, Peptic Ulcer, Functional Dyspepsia, Irritable Bowel Syndrome
- Trial name
- NCT00920400
- Where
- Switzerland
- Volunteers
- 287 people
- Sponsor
- University Hospital, Basel, Switzerland
Systemic Lupus Erythematosus, Gastrointestinal Diseases
Subclinical Gastrointestinal Involvement in Juvenile Systemic Lupus Erythematosus
This cross-sectional case-control study aims to evaluate fecal calprotectin levels and intestinal ultrasound findings for the detection of subclinical gastrointestinal involvement in children with juvenile systemic lupus…
- Trial name
- NCT07858461
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inflammatory Bowel Diseases
Urinary PGE-MUM (PROSTAGLANDIN E-MAJOR URINARY METABOLITE) as Inflammatory Marker in Chronic Inflammatory Bowel Disease
The inflammatory bowel diseases (IBD) are lifelong, relapsing-remitting diseases. As the timing of relapse is unpredictable, and current monitoring is symptoms-based, there remains a window between the initial upregulation of the…
- Trial name
- MICIMUM (NCT05171452)
- Testing
- Urine and stoll samples
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Juvenile Idiopathic Arthritis, Flare Up, Symptom
Biomarkers in Pediatric Inflammatory Rheumatic Diseases
A prospective study is proposed to serially determine new biomarkers: Calprotectin and Serum Amyloid Protein, alongside 'conventional' biomarkers: CRP and ESR, to help evaluate their utility in routine clinical practice
- Trial name
- BIRPED (NCT07356804)
- Testing
- Calprotectine
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Irritable Bowel Syndrome
Effects of Vivatlac Synbiotic on Gut Micribiota of IBS Patients
Multi-center, randomized, double-blind, placebo-controlled, 12 weeks trial investigating the effects of a nine-strain synbiotic (Vivatlac Synbiotikum) on the gut microbiota of IBS patients
- Trial name
- ViIBS3 (NCT07235228)
- Testing
- Vivatlac Synbiotic
- Where
- 2 sites in Poland
- Volunteers
- 20 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
Inflammatory Bowel Diseases
Are Rates of Colectomies, Resections, Mortalities and Cancer Reduced by Home Monitoring of IBD Patients ?
This study is a side protocol/extension of 10 years of ClinicalTrials.gov ID: NCT02492555. The purpose of this study is to determine if the IBD patients doing home monitoring (screening themselves on demand (OD) or every 3…
- Trial name
- NCT03038984
- Testing
- At Home Screening procedure On demand, At Home Screening procedure every 3 months
- Volunteers
- 120 people
- Sponsor
- Nordsjaellands Hospital
Blastocystis Infections
Efficacy of Calprotectin as A Marker For the Pathogenicity of Blastocystis Infection
Blastocystis which is commonly found in the gastro-intestinal tract, has been recognized as a non-pathogenic organism for a few decades. It has a variable distribution.
- Trial name
- NCT05724368
- Testing
- Fecal Calprotectin ELISA kit
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
FPIES
Longitudinal Study of the Intestinal, Cutaneous and Salivary Microbiota in Children With Food-induced Enterocolitis Syndrome (SEIPA)
Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non IgE-mediated allergy, presenting with vomiting, and may be complicated by hypovolemic shock.
- Trial name
- SEIBIOTE (NCT04081415)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Disease, Chronic Obstructive
Calprotectin I Serum as a Diagnostic Marker
Lower respiratory tract infection is the most common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).
- Trial name
- NCT03474484
- Where
- Norway
- Volunteers
- 113 people
- Sponsor
- St. Olavs Hospital
Diarrhea Chronic, UC - Ulcerative Colitis
ND-12 Combined With H-6 for Adult Chronic Inflammatory Diarrhea
This is a randomized controlled trial to explore the efficacy and safety of ND-12 combined with H-6 for patients with chronic inflammatory diarrhea
- Trial name
- NCT07767370
- Testing
- mesalazine, ND-12, ND-12/H-6
- Where
- China
- Volunteers
- 36 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Ulcerative Colitis Acute, Surgery
Indicators Predicting Surgery in Acute Severe Ulcerative Colitis(ASUC)
Acute severe ulcerative colitis [ASUC] patients have high risk of no response to medical treatments and might miss the best timing for surgery when waiting for the medical response.
- Trial name
- NCT03578692
- Volunteers
- 146 people
- Sponsor
- Gao Tao
Colic, Inflammation
Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Colic
This study will compare 2 currently marketed formulas in healthy full term babies: Nutramigen A+ (a hypoallergenic formula) and Nutramigen-Enflora (hypoallergenic formula with Lactobacillus GG (LGG)) during 3 months of formula…
- Trial name
- LGG (NCT01279265)
- Testing
- Nutramigen with Enflora, Nutramigen A+
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Ulcerative Colitis, Crohn's Disease
Eicosapentaenoic Free Fatty Acid and Fecal Calprotectin in Inflammatory Bowel Diseases
The aim of this study is to test Eicosapentaenoic free fatty acid's effects on calprotectin levels in IBD patients in clinical remission.
- Trial name
- NCT02179372
- Testing
- Eicosapentaenoic acid
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Severe Alcoholic Hepatitis
Assessment of the Predictive Value of Fecal Calprotectin for the Outcome of Severe Alcoholic Hepatitis
Severe alcoholic hepatitis, defined by a "Maddrey discriminant function" above 32, is associated with significant short-term mortality.
- Trial name
- CALPRO-HAA (NCT02808663)
- Testing
- fecal calprotectin concentration, blood collection
- Where
- France
- Volunteers
- 6 people
- Sponsor
- CHU de Reims
Crohn Disease, Infrared Thermography
Assessment of Intestinal Inflammation by Infrared Thermography in Pediatric Crohn Disease
The assessment of digestive inflammation and disease activity in paediatrics Crohn's disease (CD) is currently based on anamnestic, clinical and paraclinical elements such as the paediatric CD activity index (wPCDAI) , faecal…
- Conditions
- Crohn Disease, Infrared Thermography, Child
- Trial name
- THERMO-CROHN (NCT05710276)
- Testing
- abdominal infrared radiation
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Inflammatory Bowel Diseases, Calprotectin
Effect of Semi-vegetarian Diet in Inflammatory Bowel Disease Patients With Clinical Remission
In the 21st century, the incidence of inflammatory bowel disease (IBD) globally increases. Higher incidence of IBD development may implicate that environmental factors played essential roles in IBD pathogenesis.
- Conditions
- Inflammatory Bowel Diseases, Calprotectin, Fecal Microbiota, Vegetarian Diet
- Trial name
- NCT04835727
- Testing
- Semi-vegetarian diet and increase fiber consumption
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Diphtheria, Tetanus
Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™
Objectives: To present the rates of adverse reactions after a dose of DAPTACEL® vaccine administered to children 4 to 6 years of age who have previously received four doses of PENTACEL™ vaccine.
- Conditions
- Diphtheria, Tetanus, Pertussis, Polio
- Trial name
- NCT00802867
- Testing
- Diphtheria and Tetanus Toxoids and Acellular Pertussis (DAPTACEL®)
- Where
- 19 sites in United States
- Volunteers
- 989 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company