Clinical trials: S100A8
IBD (Inflammatory Bowel Disease)
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Sleep disturbances are common in patients with inflammatory bowel disease (IBD) and are associated with increased disease activity and reduced quality of life.
- Trial name
- Melatonin IBD (NCT07737665)
- Testing
- Melatonin ("Circadin")
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Ulcerative Colitis
Thermography in Surveillance of Ulcerative Colitis
Ulcerative colitis represents a chronic condition occurring in relapsing and remitting fashion with uncertain outcome and requires lifelong treatment with considerable side effects.
- Trial name
- Thermo (NCT02149043)
- Testing
- Thermography, Colonoscopy
- Where
- Croatia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Insomnia, Nonorganic, Chronic Insomnia Disorder
Individualized TCM Pattern-Based Thread-Embedding Acupuncture Plus Auricular Acupressure for Chronic Insomnia
Chronic insomnia disorder is a common sleep disorder associated with impaired daytime functioning and may be accompanied by alterations in immune-inflammatory and gut-related biological processes.
- Trial name
- NCT07552714
- Testing
- Thread embedding acupuncture, Auricular acupressure
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Diarrhea, Calprotectin
Fecal Calprotectin Level in Patients With Nosocomial Diarrhea
Nosocomial diarrhea is a common problem.There are multiple ethiologies of nosocomial diarrhea in which can be divided into inflammatory and non inflammatory diarrhea.
- Trial name
- NCT04491799
- Testing
- Fecal calprotectin
- Where
- Thailand
- Volunteers
- 135 people
- Sponsor
- Mahidol University
Infantile Colic
Effects of Multilac Baby on Fecal Calprotectin Levels of Colicky Babies
Open trial with two parallel arms, assessing the effects of Simethicone and Multilac Baby on crying behavior and fecal calprotectin levels in babies diagnosed for infantile colic.
- Trial name
- NCT04666324
- Testing
- Simethicone Solution, Multilac Baby
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
Campylobacter Infections, Irritable Bowel Syndrome
Campylobacter Enteritis and Post-Infective Bowel Dysfunction (PI-BD): Role of Antibiotics and Microbiota
The principal research objective is to determine the impact of antibiotic use on the risk of developing long term bowel symptoms after infection with the germ Campylobacter.
- Trial name
- CERAMIC (NCT02040922)
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- University of Nottingham
Cystic Fibrosis
Fecal Calprotectin in Cystic Fibrosis
Elevated fecal calprotectin is a biomarker for intestinal inflammation in cystic fibrosis
- Trial name
- NCT00863694
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Medical College of Wisconsin
Calprotectin, Cyanotic Heart Disease
Monitor Faecal Calprotectin Concentration in Infants With Heart Defects
Infants born with heart problems are at risk of developing gut disease due to reduced blood flow to the intestines which can result in poor weight gain, surgery and even death.
- Trial name
- NCT03255564
- Testing
- feacal calprotectin concentration
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Ulcerative Colitis
Predictive Factors of Endoscopic Mucosal Healing in Quiescent Ulcerative Colitis
The purpose of this study is to determine whether fecal calprotectin, fecal immunochemical test, and Rome III criteria for irritable bowel syndrome (IBS) can predict mucosal healing in patients with quiescent ulcerative colitis…
- Trial name
- PINQLE (NCT02640391)
- Testing
- colonoscopy
- Where
- South Korea
- Volunteers
- 127 people
- Sponsor
- Kyungpook National University Hospital
Inflammatory Bowel Diseases
IBDoc® Canadian User Performance Evaluation
The objective of the IBDoc® user performance evaluation is to demonstrate the ease-of-use of the IBDoc® calprotectin home test to allow patients with inflammatory bowel disease (IBD) to independently and correctly determine…
- Trial name
- NCT03408249
- Testing
- IBDoc calprotectin test, questionnaire
- Where
- 3 sites in Canada
- Volunteers
- 61 people
- Sponsor
- Bühlmann Laboratories AG
Crohn Disease, Infrared Thermography
Assessment of Intestinal Inflammation by Infrared Thermography in Pediatric Crohn Disease
The assessment of digestive inflammation and disease activity in paediatrics Crohn's disease (CD) is currently based on anamnestic, clinical and paraclinical elements such as the paediatric CD activity index (wPCDAI) , faecal…
- Conditions
- Crohn Disease, Infrared Thermography, Child
- Trial name
- THERMO-CROHN (NCT05710276)
- Testing
- abdominal infrared radiation
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Spontaneous Bacterial Peritonitis
Ascitic Fluid Calprotectin as an Accurate Diagnostic Marker for Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is an infection of the ascitic fluid in patients with liver cirrhosis and portal hypertension.
- Trial name
- NCT05422118
- Testing
- ascitic fluid calprotectin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
IBD (Inflammatory Bowel Disease), IBS - Irritable Bowel Syndrome
ALPCO/Calprotectin CLIA Assay: Expected Values of Calprotectin in Healthy Subjects
This study is evaluating the levels of calprotectin, a protein found in stool, in healthy adults. Calprotectin is a marker of inflammation in the intestines and can help doctors tell the difference between inflammatory bowel…
- Conditions
- IBD (Inflammatory Bowel Disease), IBS - Irritable Bowel Syndrome, Crohn Disease (CD), UC - Ulcerative Colitis
- Trial name
- NCT07089420
- Testing
- ALPCO Calprotectin CLIA
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Ulcerative Colitis (UC)
Predictive Efficacy of Fecal Calprotectin Assay by Magnetic Particle Chemiluminescence for Mucosal Healing in Moderate-to-Severe Ulcerative Colitis Patients Undergoing Initial Biologic Therapy（PRECAL）
This is a national prospective, multicenter, observational study. A total of 200 eligible patients will be enrolled from 10 hospitals across the country.
- Trial name
- PRECAL (NCT07721441)
- Testing
- fecal calprotectin test
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- Tang-Du Hospital
Inflammatory Bowel Disease, Crohn's Disease
FOCUS: The Future of Fecal Calprotectin Utility Study for the Diagnosis and Management of Inflammatory Bowel Disease (IBD)
Hypothesis: Fecal Calprotectin will be useful in guiding the diagnosis and management of patients with Inflammatory Bowel Disease.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- FOCUS (NCT01676324)
- Where
- Canada
- Volunteers
- 289 people
- Sponsor
- University of British Columbia
Peri-Implantitis, Dental Implant Failed
Assessment of Efficacy of Calprotectin and Cross-linked N-telopeptides
The study aims to assess the efficacy of Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid as a biomarker in patients with peri-implantitis.
- Trial name
- NCT04177732
- Testing
- Collection of sulcular (crevicular) fluid, Probing depth, Bleeding on probing
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansour Assery
Crohn Disease, Calprotectin
STUDY OF THE ADDED VALUE OF A TRANSMURAL EVALUATION IN PATIENTS WITH CROHN'S DISEASE UNDER BIOTHERAPY WITH CLOSE FECAL CALPROTECTIN FOLLOW-UP
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that can dramatically affect the quality of life of patients.
- Conditions
- Crohn Disease, Calprotectin, MRI
- Trial name
- Deeper (NCT04973423)
- Testing
- MRI
- Where
- 17 sites in France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Severe Colitis (ASC)
Ulcerative Colitis Endoscopic Index of Severity and Fecal Calprotectin to Predict the Reaction to Corticosteroids of Acute Severe Ulcerative Colitis
For acute severe colitis (ASC) patients, corticosteroids (CS) was recommended as the first-line treatment in the guideline, but patients have a great risk of requiring colectomy or turning to second-line treatment.
- Trial name
- NCT02922374
- Testing
- corticosteroids
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Jinling Hospital, China
Enterocolitis, Necrotizing, Premature Infant
NEC Screening Abdominal Radiograph vs Bowel Ultrasound in Preemies
The overall primary objective is to establish the feasibility and pilot the design and delivery of a diagnostic randomized controlled trial (RCT) of BUS (bowel ultrasound) for NEC evaluation which will lead to a successful…
- Trial name
- NCT03963011
- Testing
- Bowel Ultrasound
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Children's Mercy Hospital Kansas City
Irritable Bowel Syndrome
Association Between High Faecal Calprotectin, Increased Intestinal Permeability and Visceral Hypersensitivity in IBS-D Patients
Visceral hypersensitivity, low grade inflammation and increased intestinal permeability are three main pathophysiological mechanisms involved in irritable bowel syndrome. The connexion between these abnormalities is not known.
- Trial name
- SIIMPA (NCT02550704)
- Testing
- Colonoscopy with eleven biopsies in the left colon to assess intestinal permeability
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Rouen