Clinical trials: SAR
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.
- Trial name
- NCT00295022
- Testing
- Montelukast, Levocetirizine
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- UCB S.A. - Pharma Sector
Biochemical Recurrence of Malignant Neoplasm of Prostate
64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA)
The aim of this study is to determine the safety and efficacy of 64Cu-SAR-bisPSMA and determine the ability of 64Cu-SAR-bisPSMA Positron emission tomography (PET)/computed tomography (CT) to correctly detect the recurrence of…
- Trial name
- COBRA (NCT05249127)
- Testing
- 64Cu-SAR-bisPSMA
- Where
- 5 sites in United States
- Volunteers
- 52 people
- Sponsor
- Clarity Pharmaceuticals Ltd
Seasonal Allergic Rhinitis, SAR
Study of an Investigational Nasal Aerosol or Placebo Nasal Aerosol in Children (Ages 6-11) With Seasonal Allergies
The purpose of this study is to assess the safety and efficacy of an investigational nasal aerosol at two doses compared with placebo nasal aerosol in the treatment of seasonal allergic rhinitis in children (6-11 years of age).
- Trial name
- NCT01307319
- Testing
- BDP HFA
- Where
- 45 sites in United States
- Volunteers
- 715 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Seasonal Allergic Rhinitis
POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)
Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
- Trial name
- NCT00160537
- Testing
- Levocetirizine
- Volunteers
- 200 people
- Sponsor
- UCB Pharma
SAR
A Prospective Study of Stapokibart Injection in Patients With Seasonal Allergic Rhinitis (SAR)
This study is an open label, prospective study to evaluate the safety of Stapokibart Injection in subjects with SAR.
- Trial name
- NCT07459556
- Testing
- Stapokibart
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chengdu Kangnuoxing Biopharma,Inc.
Seasonal Allergic Rhinitis
Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis
This study will assess the efficacy and safety of different doses of ACT-129968 in adult patients with seasonal allergic rhinitis, due to mountain cedar pollen.
- Trial name
- SAR (NCT01241214)
- Testing
- ACT-129968, Cetirizine
- Where
- 7 sites in United States
- Volunteers
- 579 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Seasonal Allergic Rhinitis
A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Seasonal Allergic Rhinitis
This is a randomized, double-blind phase II clinical study to evaluate the efficacy and safety of AK139 in the treatment of participants with moderate to severe SAR
- Trial name
- NCT07436234
- Testing
- AK139
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Akeso
Seasonal Allergic Rhinitis (SAR), Allergic Rhinitis
Evaluation of the Efficacy, Safety, and Tolerability of PL-14 Allergy Blocker Compared to Saline Spray in Patients With Seasonal Allergic Rhinitis
This study is designed to evaluate the efficacy, safety, and tolerability of PL-14 Allergy Blocker compared to saline spray in adults with Seasonal Allergic Rhinitis (SAR).
- Trial name
- NCT07588672
- Testing
- PL-14 Allergy Blocker, Ayr® Saline Nasal Mist
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Polyrizon Ltd.
Seasonal Allergic Rhinitis (SAR)
Study of Stapokibart Injection in Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)
This study is a multicenter, single-arm, open-label, phase II study to evaluate the safety, pharmacokinetics, and immunogenicity of Stapokibart injection in Adolescent Patients with SAR.
- Trial name
- NCT07617324
- Testing
- Stapokibart injection
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Chengdu Kangnuoxing Biopharma,Inc.
Seasonal Allergic Rhinitis
Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR
The primary objective of this study was to compare the relative efficacy of Budesonide administered via Captisol-Enabled Budesonide nasal solution and Rhinocort Aqua in patients with seasonal allergic rhinitis (SAR) exposed to…
- Trial name
- NCT00938613
- Testing
- Budesonide
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Ligand Pharmaceuticals
Seasonal Allergic Rhinitis, Hay Fever
PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)
The purpose of this study is to evaluate the relative efficacy of four dosing regimens of bilastine tablets versus placebo in subjects with SAR exposed in controlled ragweed pollen using the EEC model based on the mean change…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Rhinoconjunctivitis
- Trial name
- NCT00574210
- Testing
- Bilastine
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- Faes Farma, S.A.
Seasonal Allergic Rhinitis
Study of the Effect of SCH 900538 on Congestion in Subjects With Seasonal Allergic Rhinitis (Study P05031)(COMPLETED)
This study is to evaluate the effectiveness of a new drug on congestion in subjects with seasonal allergic rhinitis. This effect will be compared to placebo and to the decongestant, pseudoephedrine.
- Trial name
- NCT00673062
- Testing
- SCH 900538, Pseudoephedrine
- Volunteers
- 265 people
- Sponsor
- Merck Sharp & Dohme LLC
Dry Eye Disease
A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye
The purpose of the study is to evaluate the safety and efficacy of lifitegrast ophthalmic solution compared to placebo in the treatment of dry eye.
- Trial name
- NCT01743729
- Testing
- Lifitegrast
- Where
- 31 sites in United States
- Volunteers
- 720 people
- Sponsor
- Shire
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in Children (Aged 6 to Under 12 Years) With Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 nasal spray (NS) compared with placebo NS in pediatric subjects (aged 6 to under 12 years) with Seasonal Allergic Rhinitis (SAR).
- Trial name
- GSP 301-305 (NCT03463031)
- Testing
- GSP 301 NS
- Where
- 32 sites in United States
- Volunteers
- 446 people
- Sponsor
- Glenmark Specialty S.A.
Allergic Rhinitis, Seasonal
A Study of IL4Rα Monoclonal Antibody in Patients With Seasonal Allergic Rhinitis
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- NCT07154342
- Testing
- GR1802 injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Seasonal Allergic Rhinitis
Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis
To demonstrate the efficacy of ciclesonide HFA applied as a nasal aerosol (160 μg and 80 μg) once daily compared to placebo in subjects with SAR.
- Trial name
- NCT00790023
- Testing
- 80 mcg Ciclesonide, 160 mcg Ciclesonide
- Where
- 4 sites in United States
- Volunteers
- 707 people
- Sponsor
- Sumitomo Pharma America, Inc.
Rhinitis, Seasonal, Allergic
StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study
This active vs active comparative trial will evaluate the safety and efficacy of incremental doses of atropine in combination with pseudoephedrine 120 mg/chlorpheniramine 8 mg in adult patients with a history of seasonal allergic…
- Trial name
- NCT02082054
- Testing
- PSE 120 mg, CM 8 mg, Atr 0.36 mg, PSE 120 mg, CM 8 mg, Atr 0.24 mg, PSE 120 mg, CM 8 mg, Atr 0.12 mg
- Where
- 4 sites in United States
- Volunteers
- 125 people
- Sponsor
- Magna Pharmaceuticals, Inc.
Rhinitis, Allergic, Seasonal, Hay Fever
To Assess the Safety and Efficacy of Ciclesonide, Applied as a Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (BY9010/M1-401)
The primary objective of this study is to demonstrate the efficacy of ciclesonide applied as a nasal spray once daily in patients with SAR. The secondary objectives are to evaluate Quality-of-Life and safety.
- Trial name
- NCT00659841
- Testing
- Ciclesonide
- Where
- 6 sites in United States
- Volunteers
- 302 people
- Sponsor
- AstraZeneca
Seasonal Allergic Rhinitis
A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Seasonal Allergic Rhinitis (SAR)
This is a 2-week, multicenter, randomized, double-blind, placebo-controlled, parallel group, efficacy and safety study of ciclesonide nasal aerosol administered once daily to male and premenarchal female subjects 6 to 11…
- Trial name
- NCT01458275
- Testing
- Ciclesonide nasal aerosol 37 mcg, ciclesonide nasal aerosol 74 mcg
- Where
- 66 sites in United States
- Volunteers
- 847 people
- Sponsor
- Sumitomo Pharma America, Inc.
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy and safety of GSP 301 NS compared to placebo NS and to individual monotherapies (comparators) as well as the efficacy of these monotherapies (comparators) versus placebo NS over 14 days of study…
- Trial name
- GSP 301-301 (NCT02631551)
- Testing
- GSP 301 NS, Olopatadine HCl NS, Mometasone furoate NS
- Where
- 37 sites in United States
- Volunteers
- 1,180 people
- Sponsor
- Glenmark Specialty S.A.