Clinical trials: SAR
Seasonal Allergic Rhinitis
Safety and Efficacy Trial of Dymista Nasal Spray in Children Ages 4 to 11 With Seasonal Allergic Rhinitis (SAR)
The purpose of this study is to determine if Dymista nasal spray is better and safer than placebo in treating children ages 4 to <12 years old who have seasonal allergic rhinitis.
- Trial name
- NCT01915823
- Testing
- azelastine hydrochloride and fluticasone propionate, Dymista vehicle
- Where
- 31 sites in United States
- Volunteers
- 348 people
- Sponsor
- Meda Pharmaceuticals
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 NS compared with placebo NS and individual monotherapy formulations for the treatment of Seasonal Allergic Rhinitis (subjects 12 years of age and older)
- Trial name
- GSP 301-304 (NCT02870205)
- Testing
- GSP 301 NS, GOM-NS, GMM-2 NS
- Where
- 43 sites in United States
- Volunteers
- 1,176 people
- Sponsor
- Glenmark Specialty S.A.
Seasonal Allergic Rhinitis, Hay Fever
Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)
The purpose of the study is to assess the efficacy and safety of an investigational nasal aerosol compared with placebo nasal aerosol in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT01024608
- Testing
- Beclomethasone dipropionate
- Where
- 4 sites in United States
- Volunteers
- 340 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Allergic Conjunctivitis
Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR)
To evaluate the efficacy of olopatadine 0.1% using the OHIO Chamber in patients with seasonal allergic conjunctivitis.
- Trial name
- NCT00818805
- Testing
- Olopatadine 0.1%, Tranilast 0.5%
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Rhinitis, Allergic, Seasonal, Asthma
Nasonex Compared With Placebo in Participants With Seasonal Allergic Rhinitis (SAR) and Concomitant Asthma (P03280)
This study will compare mometasone nasal spray to placebo in treating the nasal and asthma symptoms experienced by participants with seasonal allergic rhinitis (SAR) and concomitant asthma.
- Trial name
- NCT00070707
- Testing
- Mometasone, Albuterol/Salbutamol
- Volunteers
- 188 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00728416
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 333 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579)
This is a Phase 3, single-dose, investigator-blind, randomized, placebo-controlled, crossover study, conducted at a single site in Austria, outside of the normal grass pollen season.
- Trial name
- NCT00276016
- Testing
- phenylephrine, pseudoephedrine
- Volunteers
- 39 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05528)(COMPLETED)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00733005
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 324 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis, Hayfever
Study to Assess the Efficacy and Safety of BDP HFA Nasal Aerosol in Patients 12 Years and Older With SAR
This is a phase 2, randomized, double-blind, placebo-controlled, parallel-group, 2-week, multi-center, dose-range-finding study in male or female patients (12 years and older) with SAR.
- Trial name
- NCT00854360
- Testing
- Beclomethasone dipropionate HFA Nasal Aerosol
- Where
- 26 sites in United States
- Volunteers
- 487 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Seasonal Allergic Rhinitis
To Study GSP 301 in Patients With Seasonal Allergic Rhinitis
Study to evaluate the two different strengths and dose regimen of GSP 301 to be effective in treatment of seasonal allergic rhinitis.
- Trial name
- NCT02318303
- Testing
- GSP 301-1 NS (QD), GSP 301-2 NS (BID), Olopatadine HCl-1 NS (QD)
- Where
- 10 sites in United States
- Volunteers
- 1,111 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Rhinitis, Allergic, Seasonal
A 5-way Treatment Period Trial of Single Doses of Intranasal GSK256066 in Patients With Rhinitis
This current study is planned as a dedicated pharmacodynamic (effect of drug on the body) study to investigate the dose response in rhinitic subjects at doses where GSK256066 has been proven to work (200mcg) or expected to…
- Trial name
- NCT00464568
- Testing
- GSK256066
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Keratoconjunctivitis Sicca, Dry Eye Disease
Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1)
The purpose of the study is to evaluate the efficacy of SAR 1118 Ophthalmic Solution (5.0%) compared to placebo in the treatment of Dry Eye.
- Trial name
- OPUS-1 (NCT01421498)
- Testing
- Lifitegrast
- Where
- 13 sites in United States
- Volunteers
- 588 people
- Sponsor
- Shire
Biochemical Recurrence of Malignant Neoplasm of Prostate
64Cu-SAR-BBN for Identification of Participants With Recurrence of Prostate Cancer (SABRE)
The aim of this study is to determine the safety and efficacy of 64Cu-SAR-BBN and determine the ability of 64Cu-SAR-BBN Positron emission tomography (PET)/computed tomography (CT) to correctly detect the recurrence of prostate…
- Trial name
- SABRE (NCT05407311)
- Testing
- 64Cu-SAR-BBN
- Where
- 8 sites in United States
- Volunteers
- 53 people
- Sponsor
- Clarity Pharmaceuticals Ltd
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00732381
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 351 people
- Sponsor
- Organon and Co
Allergic Conjunctivitis
Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis
The purpose of this study is to determine whether SAR 1118 at three different concentrations, compared to placebo, is effective in the prevention of the signs and symptoms of allergic conjunctivitis
- Trial name
- NCT00882687
- Testing
- Lifitegrast
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shire
Seasonal Allergic Rhinitis
Bepotastine Besilate Nasal Sprays in the Treatment of Seasonal Allergic Rhinitis (SAR)
This study will examine dose ranging characteristics of bepotastine besilate nasal spray compared to placebo nasal spray in 600 male or female subjects 12 years of age and older with active seasonal allergic rhinitis (SAR) and a…
- Trial name
- NCT01753739
- Testing
- Bepotastine besilate
- Where
- United States
- Volunteers
- 617 people
- Sponsor
- Bausch & Lomb Incorporated
Seasonal Allergic Rhinitis
Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis (SAR) to Mountain Cedar in Subjects 12 Years and Older
This clinical research study will evaluate the safety and effectiveness of two doses of an investigational medication (ciclesonide nasal aerosol) for the treatment of subjects with of seasonal allergic rhinitis (SAR).
- Trial name
- NCT01010971
- Testing
- Ciclesonide HFA 160 μg, Ciclesonide HFA 80 μg
- Where
- 7 sites in United States
- Volunteers
- 671 people
- Sponsor
- Sumitomo Pharma America, Inc.
Rhinitis, Allergic, Perennial and Seasonal
A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis
This phase IV investigational trial is being conducted to evaluate the efficacy of a 2-week treatment of fluticasone propionate nasal spray (FPNS) vs.
- Trial name
- NCT01916226
- Testing
- FPNS, Cetirizine
- Where
- 31 sites in United States
- Volunteers
- 682 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic
A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen
The purpose of the study is to assess the efficacy comparability of cetirizine and levocetirizine, by comparing the effects of single intake of the two drugs to placebo in reducing symptoms of seasonal allergic rhinitis (SAR) in…
- Conditions
- Rhinitis, Allergic, Seasonal
- Trial name
- NCT00291642
- Testing
- Levocetirizine drops, Levocetirizine tablets
- Where
- Canada
- Volunteers
- 551 people
- Sponsor
- UCB Pharma
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.
- Trial name
- NCT00295022
- Testing
- Montelukast, Levocetirizine
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- UCB S.A. - Pharma Sector