Clinical trials: SARS-COV-2 Infection
COVID-19, SARS-CoV-2
Azithromycin for COVID-19 Treatment in Outpatients Nationwide
This individually randomized telemedicine-based trial aims to evaluate the efficacy of a single dose of azithromycin for prevention of progression of COVID-19 in patients with a recent positive SARS-CoV-2 test who are not…
- Trial name
- ACTION (NCT04332107)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Thomas M. Lietman
A Multilevel, Tailored COVID-19 Testing Condition, A Nontailored COVID-19 Testing Control Condition
A Faithful Response to COVID-19 Project
This 2-arm clustered, randomized community trial will test a multilevel, COVID-19 testing and linkage to care (eg, health insurance, medical appointments, community resources, contact tracing) intervention against a nontailored…
- Trial name
- FR (NCT04978207)
- Testing
- A Faithful Response to COVID-19
- Where
- 10 sites in United States
- Volunteers
- 1,013 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Myocardial Injury, Myocarditis
Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study)
The study will focus on cardiac blood and imaging biomarkers to facilitate early recognition of patients at risk for myocardial injury after COVID-19 vaccination.
- Conditions
- Myocardial Injury, Myocarditis, COVID-19 Vaccination, SARS-CoV-2
- Trial name
- MYOVAX (NCT04967807)
- Testing
- Cardiac PET/MRI, Blood Biomarkers
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Colorectal Neoplasms Malignant
Effects of COVID-19 Pandemic on the Outcomes of Colorectal Cancer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been identified as the cause of the Coronavirus disease 19 (COVID-19), which was initially reported in December 2019 in China and has since rapidly spread…
- Trial name
- COVID-CRC (NCT04712292)
- Testing
- Surgical procedure for confirmed or suspected colorectal cancer
- Where
- 45 sites in Italy
- Volunteers
- 15,000 people
- Sponsor
- University of Bologna
Immunologic Activity Alteration
Asymptomatic COVID-19 Infection Among Healthcare Workers
To assess the seroprevalence of SARS-CoV-2 IgG in Health care workers in three University Hospitals
- Trial name
- NCT04354792
- Testing
- Serum SARs COV 2 IGg screening in health care workers
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Covid19
Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis
Predi-COVID is a prospective cohort study composed of people positively tested for COVID-19 in Luxembourg, followed digitally for monitoring participants' health evolution and symptoms at home.
- Trial name
- Predi-COVID (NCT04380987)
- Testing
- Biological sampling
- Where
- Luxembourg
- Volunteers
- 1,366 people
- Sponsor
- Luxembourg Institute of Health
COVID-19 Acute Respiratory Distress Syndrome, Respiration, Artificial
Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19
Flow controlled ventilation (FCV) is a fairly new mode of mechanical ventilation, consisting of a constant inspiratory and expiratory flow. Inspiration is thus comparable to volume controlled ventilation (VCV).
- Trial name
- VICAR (NCT04894214)
- Testing
- Arterial blood gas (ABG), Recording of hemodynamic monitoring, Recording of respiratory monitoring
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- University Hospital, Antwerp
Moderate COVID-19-infection
Viable Human SARS-CoV-2 Specific T Cell Transfer in Patients at Risk for Severe COVID-19
Monocentric open phase I (dose escalation component), followed by a multi-center, randomized, phase II component benchmarking IMP+SoC against SoC
- Trial name
- ACT-COVID-19 (NCT04762186)
- Testing
- human SARS-CoV 2 specific T lymphocytes
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Universitätsklinikum Köln
Covid-19, SARS
Tocilizumab vs CRRT in Management of Cytokine Release Syndrome (CRS) in COVID-19
Some patients infected with the COVID-19 can develop uncontrolled immune response, leading to potentially life-threatening damage to lung tissue. Tocilizumab was first approved by the U.S.
- Conditions
- Covid-19, SARS, Cytokine Storm, Cytokine Release Syndrome
- Trial name
- TACOS (NCT04306705)
- Testing
- Tocilizumab, Standard of care, Continuous renal replacement therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
COVID-19
Retrospective Study of COVID-19 on Reproductive Function
This multi-center, retrospective cohort study aimed to determine which factors are associated with ongoing pregnancy rates in infertile patients received ART treatments during the current outbreak of COVID-19 infection.Couples…
- Trial name
- NCT05685966
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Jinling Hospital, China
Covid-19 in Pregnancy
Impact of COVID-19 Infection During Pregnancy
To asses impact of the COVID-19 infection during Pregnancy on maternal and fetal outcome in relation to gestational age.
- Trial name
- NCT05139953
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Menoufia University
Covid19
Study on Prevention of SARS-CoV-2 Transmission During a Large Indoor Gathering Event
The objective is to demonstrate if there is no increase in the risk of Sars-Cov-2 salivary carriage 7 days after a concert in the group participating in the event compared to a non participating group who stayed at home.
- Trial name
- SPRING (NCT04872075)
- Testing
- Concert, Rapid nasopharyngeal antigen test for Sars-Cov-2, Saliva Sample
- Where
- France
- Volunteers
- 6,678 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19
A Wearable, Battery-free Screening System for SARS-CoV-2, the Virus Causing COVID-19 Infection
The corona virus disease (COVID) pandemic has highlighted the importance of rapid, readily available screeners and diagnostics to identify infected individuals.
- Trial name
- NCT04807075
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Nebraska
COVID-19
Therapy for Pneumonia Patients iInfected by 2019 Novel Coronavirus
The 2019 novel coronavirus pneumonia outbroken in Wuhan, China, which spread quickly to 26 countries worldwide and presented a serious threat to public health.
- Trial name
- NCT04293692
- Testing
- UC-MSCs
- Where
- China
- Sponsor
- Puren Hospital Affiliated to Wuhan University of Science and Technology
Acute Coronary Syndrome, Chronic Heart Failure
Influenza Vaccination During Coronavirus Disease 2019 Outbreak After Acute Coronary Syndrome and Chronic Heart Failure
Study Description: Background: Well-known fact that the number of cardiovascular diseases is on the rise during influenza epidemic.
- Trial name
- IV-ACS&CHF (NCT05232292)
- Testing
- Ultrix Quadri
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara Regional Cardiology Dispensary
SARS-CoV2 Infection
The School SPIT Study - Elementary Schools in High COVID-19 Incidence Regions
This study will conduct an evaluation of a program that is being implemented SickKids / Toronto Public Health that provides take-home saliva testing kits in schools.
- Trial name
- NCT05055492
- Testing
- Take home saliva kits
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
COVID-19
Expanded Access to Convalescent Plasma to Treat and Prevent Pulmonary Complications Associated With COVID-19
I. Study Design: This is a single-arm feasibility study to assess the safety and efficacy of anti-SARS-CoV-2 convalescent plasma (CP) in 1.
- Trial name
- NCT04358211
- Testing
- Biological: COVID-19 convalescent plasma
- Where
- United States
- Sponsor
- Nakhle Saba, MD
Covid19
Vital Sensor Monitors for CV19 Detection
This study will monitor physical bio-markers such as heart rate, respiratory rate, and temperature to detect potential COVID-19 infections.
- Trial name
- NCT04635787
- Testing
- ANNE One
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Northwestern University
Post-Acute COVID-19 Syndrome
Incidence, Associated Factors, and Burden of Post COVID-19 Condition in Brazil
This is a national retrospective cohort study with internet-based recruitment which intends to enroll 1,694 adult patients with COVID-19 diagnosis during the SARS-CoV-2 omicron wave in Brazil.
- Trial name
- NCT05822193
- Testing
- Multiple exposures
- Where
- Brazil
- Volunteers
- 1,694 people, healthy volunteers welcome
- Sponsor
- Inova Medical
Vaccination Refusal
Increasing COVID-19 Vaccine Uptake in Developing Countries (Bihar)
Working with governments in Bihar, India, we will evaluate a number of mechanisms to increase vaccine uptake. These include household vaccination visits instead of community vaccination clinic.monetary and non-monetary…
- Trial name
- NCT05225064
- Testing
- Incentives to be vaccinated, Mask, Encouragement to wear a mask
- Where
- India
- Volunteers
- 114,512 people, healthy volunteers welcome
- Sponsor
- Yale University