Clinical trials: SARS-COV-2 Infections
Covid19
Remote Video Consultation for Quality of Life Assessment in Patients Hospitalised After COVID-19 Infection
Around 90.000 patients have been hospitalised due to COVID-19 infection in France between March 1st and June 15th; 19% of those requiring intensive care.
- Trial name
- TELECOVID (NCT04714138)
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Groupe Hospitalier du Havre
Type2 Diabetes, Covid19
Advancing DSME/S and COVID-19 Prevention and Protection Through "emPOWERed to Change" Program
African Americans (AA)/People of Color (POC) are disproportionately impacted by COVID-19 to an extent not observed in other racial/ethnic subgroups.
- Trial name
- NCT04993326
- Testing
- emPOWERed To Change Program
- Sponsor
- Charles Drew University of Medicine and Science
Cholangitis, Secondary Biliary, Cholangiocarcinoma
Advanced Endoscopy During COVID-19
In this study, investigators aim to explore the status of advanced endoscopy in different endoscopy units all over the world.
- Conditions
- Cholangitis, Secondary Biliary, Cholangiocarcinoma, Obstructive Jaundice, Pancreas Cancer
- Trial name
- NCT04385147
- Testing
- Endoscopic management according to standard of care
- Where
- 5 sites in United States, Egypt and 3 more
- Volunteers
- 670 people
- Sponsor
- Al-Azhar University
Cancer, Elderly
COVID-19-Study of Immune Responses Following Vaccination Against SARS-CoV-2
T-cell adaptive immunity is known to be required to sustain a long term immunoglobulin production and a long term memory against several infections.
- Conditions
- Cancer, Elderly, Healthy Aging
- Trial name
- CACOV-VAC (NCT04836793)
- Testing
- Additional biological samples
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stroke (CVA) or TIA
Stroke Care During the COVID-19 Pandemic
Background: The SARS-CoV-2 pandemic led to substantial changes in the allocation of healthcare resources and affected the behavior of patients experiencing stroke symptoms.
- Trial name
- NCT07795021
- Testing
- statistical analysis
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 40,000 people
- Sponsor
- Dr. Yaroslav Winter
COVID-19, Respiratory Failure
Azithromycin Added to Hydrochloroquine in Patients Admitted to Intensive Care With COVID-19: Randomised Controlled Trial
Trial design: Prospective, multi-centre, randomised, pragmatic, double blind trial Methods: Participants: Adult (>18 years) within 24 hours of admission to intensive care unit with proven or suspected COVID-19 infection, whether…
- Trial name
- AZIQUINE-ICU (NCT04339816)
- Testing
- Azithromycin, Hydroxychloroquine
- Where
- Czechia
- Volunteers
- 3 people
- Sponsor
- Frantisek Duska, MD, PhD
Post-Viral Fatigue Syndrome
Low-dose Naltrexone for Post-COVID Fatigue Syndrome
This study aims to determine if low-dose naltrexone (LDN) reduces fatigue, improves related symptoms, and reduces inflammatory markers in peripheral blood in cases with Post-COVID-19 Fatigue Syndrome (PCFS) from COVID-19 (i.e.
- Trial name
- NCT05430152
- Testing
- Low-Dose Naltrexone
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Luis Nacul
Pregnancy Complications, Covid19
Vitamin D Supplementarion in Pregnant Women at Risk and COVID-19
Vitamin D defiency during pregnancy is a major public health problem worldwide; In Spain, the average intake of vitamin D is lower than recommendations in an elevated percentage of the population, ranging from 50 to 95%…
- Trial name
- D-WOMAN (NCT04825093)
- Testing
- Vitamin D supplementation in pregnant women
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
COVID-19
Impact of the COVID-19 Pandemic on the Organization of Healthcare in France
The 2020 COVID-19 pandemic, which began spreading on January 24, 2020 in France, has required a profound and rapid reorganization of the health system, based in particular on internal hospital reorganizations of front-line…
- Trial name
- IRIS (NCT05013047)
- Where
- France
- Volunteers
- 100,000 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Immune Response
Comparative Analysis of Anti-COVID-19 (Severe Acute Respiratory Syndrome) Humoral and Memory T Cell Responses in Children With Various Degrees of Immunosuppression:
Adaptive immune responses are essential for clearing viral infections and retention of virus specific memory populations is required for long-term immunity.
- Trial name
- PEDIMMCO (NCT04916847)
- Testing
- blood collection
- Where
- France
- Volunteers
- 205 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Education
Distance and Hybrid Learning for Dental Student During COVID-19 Pandemic
To assess dental student opinion about distance educational learning environment during COVID-19 Pandemic and to assess their satisfaction with Hybrid learning
- Trial name
- NCT04401371
- Where
- Egypt
- Volunteers
- 376 people
- Sponsor
- Cairo University
Covid19, Retina Injury
COVID-19 Patient Cohort: Retinal Damage in Non-invasive Retinal Imaging (OCTA)
The objective of this research is to build a collection of non-invasive retinal imaging (OCT and OCTA) in order to investigate the incidence and impact of retinal damage in patients who have or have had COVID-19.
- Trial name
- NCT04881253
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
COVID-19 Acute Respiratory Distress Syndrome
Prognostic Value of PtcO2 in Patients With COVID-19
Five percent of patients with COVID-19 progressed to respiratory failure and required ICU admission, such patients often have abnormal oxygen tolerance.
- Trial name
- NCT05682612
- Testing
- outcome, Subtype of COVID-19
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
Obesity, Covid19
Social and Psychological Impacts of SARS-Cov-2 Pandemic Period in the Obese Population.
The population suffering from obesity is particularly at risk during this pandemic period. The Nouvelle Aquitaine region is not spared, since according to the regional epidemiological report of 7 May 2020, carried out by Santé…
- Trial name
- OBIMPACOV (NCT04910607)
- Testing
- Questionnaire, Interview
- Where
- 3 sites in France
- Volunteers
- 279 people
- Sponsor
- University Hospital, Bordeaux
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
COVID-19, ARDS, Human
Curosurf® in Adult Acute Respiratory Distress Syndrome Due to COVID-19
Surfactant replacement therapy (SRT) improves oxygenation and survival in NRDS and some infant ARDS. SRT was tried in adult ARDS with conflicting results.
- Trial name
- Caards-1 (NCT04384731)
- Testing
- poractant alfa
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Dr Christophe LENCLUD
COVID-19
Evaluate the Efficacy and Safety of Oral Hydroxychloroquine, Indomethacin and Zithromax in Subjects With Mild Symptoms of COVID-19
Currently there are no US Food and Drug Administration (FDA)-approved drugs specifically for the treatment of patients with COVID-19.
- Trial name
- COVID-19 (NCT04344457)
- Testing
- Hydroxychloroquine, Indomethacin, Zithromax Oral Product
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Perseverance Research Center, LLC
Covid19
Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019
The purpose of this study is to determine the effect of sacubitril/valsartan versus placebo on markers of cardiac injury, structure, and function among patients who recovered from acute COVID-19 infection.
- Trial name
- PARACOR-19 (NCT04883528)
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto]
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Duke University
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Coronavirus
Convalescent Plasma to Limit Coronavirus Associated Complications
Researchers are trying to assess the treatment potential and safety of anti-SARS-CoV-2 convalescent plasma in patients with acute respiratory symptoms with confirmed COVID-19.
- Trial name
- NCT04325672
- Testing
- Convalescent Plasma
- Sponsor
- Mayo Clinic
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