Clinical trials: SARS-COV-2 Infections
Covid19
Extracorporeal Blood Purification as a Treatment Modality for COVID-19
Several studies have suggested a potential clinical benefit of controlling hyper inflammation triggered by SARS-CoV-2/COVID-19. Blood purification, the removal of excessive proinflammatory mediators may control disease…
- Trial name
- NCT04478539
- Testing
- Extracorporeal blood purification using the oXiris® (AN69ST) hemofilter
- Where
- North Macedonia
- Volunteers
- 35 people
- Sponsor
- Zan Mitrev Clinic
COVID-19 Pneumonia
NO-mediated Vascular Function in Covid-19 Patient
The 2019 coronavirus-induced infection (COVID-19) has caused a pandemic that has spread worldwide. Up to date, many subjects affected by the virus report important sequelae on different organs increasing morbidity and…
- Trial name
- NCT04625036
- Testing
- Single passive leg movement
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Annexin A1, Adrenal Cortex Hormones
Annexin A1 Levels in SARS-CoV-2 Infection
The present study aims to determine the clinical predictivity value of blood AnxA1 levels in patients with mild and severe/critical pneumonia induced by COVID-19 and to reveal the alterations of blood AnxA1 levels in patients…
- Trial name
- NCT04948229
- Testing
- Blood serum samples
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Kafkas University
COVID-19
Immunogenicity And Safety of COVID-19 Vaccine , Inactivated Co -Administration With EV71 Vaccine (Vero Cell)
This study is a randomized and controlled Phase IV clinical trial of the COVID-19 vaccine (Vero cell), Inactivated manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT05107557
- Testing
- Experimental Group
- Where
- 2 sites in China
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
COVID-19
Utility of Lactoferrin as a Preventive Agent for Healthcare Workers Exposed to COVID-19
COVID 19, which probably started from zoonotic transmission related to crowded markets in China was announced as a pandemic by the WHO on 11 March 2020.
- Trial name
- NCT04427865
- Testing
- prophylactic lactoferrin daily
- Volunteers
- 200 people
- Sponsor
- Cairo University
COVID-19
The Safer At School Early Alert HUB
Schools serve important community roles beyond academic education. In historically marginalized communities they are trusted providers for a range of support services for families in need.
- Trial name
- SASEA HUB (NCT05642000)
- Testing
- SASEA HUB
- Where
- United States
- Volunteers
- 1,029 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
SARS-CoV2 Infection
LIPId Profile Changes in Inflammatory Conditions Induced by SARS-CORoronavirus-2
In late 2019, a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of COVID-19 (COronaVIrus Disease-2019) in Hubei Province, China.
- Trial name
- LIPICOR (NCT05113836)
- Testing
- Deep nasopharyngeal swab, Blood sample at D1, D3 and D7
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Hydroxychloroquine for the Treatment of Mild COVID-19 Disease
The current outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is a global health emergency with a case fatality rate so far approximately 4% and a growing…
- Trial name
- COMIHY (NCT04340544)
- Testing
- Hydroxychloroquine
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- University Hospital Tuebingen
Covid19, Children, Only
SeroCovid<19: Covid-19 Seroconversion in Tertiary Pediatric Patients
Children are relatively spared from the direct clinical impact of COVID-19. Pediatric patients with regular follow-up at tertiary pediatric centres and presenting one or more chronic conditions might be at increased risk for…
- Trial name
- NCT04615000
- Testing
- SARS-CoV-2 serological assessment (IgG)
- Where
- Belgium
- Volunteers
- 362 people
- Sponsor
- University Hospital, Ghent
SARS-CoV-2 Infection, Influenza A
Project STARFISH - PRJ0002679
This is a non-interventional study to perform the clinical performance evaluation of the Starfish Test using prospectively collected matched nasopharyngeal and nasal swab samples from the same donor.
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza Type B, RSV Infection
- Trial name
- STARFISH (NCT05727202)
- Testing
- The Applied Biosystems™ TaqPath™ COVID-19, Flu A, Flu B, RSV Select Panel
- Where
- 17 sites in United States
- Volunteers
- 1,909 people
- Sponsor
- Thermo Fisher Scientific, Inc
Bioavailability
Relative Bioavailability Study of 4 Different Formulations of PF-07321332 Relative to the Commercial Tablet Formulation
The purpose of this study is to estimate the relative bioavailability of PF-07321332 in different formulations in healthy adult participants.
- Trial name
- NCT05263895
- Testing
- PF-07321332/ritonavir, PF-07321332
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Covid-19
The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19
There are currently no antiviral drugs with proven efficacy nor are there vaccines for its prevention. Unfortunately, the scientific community has little knowledge of the molecular details of SARS-CoV-2 infection.
- Trial name
- NCT04468139
- Testing
- Quercetin, bromelain, Zinc
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Ministry of Health, Saudi Arabia
COVID19
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED
The spread of novel Coronavirus (2019-nCoV) related infection (COVID-19) has led to many patient presentations in the emergency department for respiratory complaints, with many of these patients requiring ICU admission and…
- Trial name
- NO COV-ED (NCT04338828)
- Testing
- Nitric Oxide Gas, Inhaled Supplemental Oxygen
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Massachusetts General Hospital
Covid19, Sars-CoV-2 Infection
Performance Study of SONA Saliva C-19 Rapid Test
The Sona Saliva C-19 Rapid Test is a bioassay intended for rapid point-of-care detection of the SARS-CoV-2 virus. Performance of the Sona Saliva C-19 Rapid Test assay will be assessed by comparison to a RT-PCR reference method
- Conditions
- Covid19, Sars-CoV-2 Infection, Corona Virus Infection
- Trial name
- NCT04877002
- Testing
- Sona Saliva C-19 Rapid Test
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sona Nanotech Inc
Complication of Medical Care, Pneumonia, Viral
Antiviral Drugs on the Treatment of SARS-CoV-2
Retrospective Non-Randomized Analytical Cohort Study of Completed SARS-CoV2 COVID19 Cases
- Trial name
- FavRem (NCT04727775)
- Testing
- Favipiravir, Remdesivir
- Where
- 2 sites in Kazakhstan
- Volunteers
- 150 people
- Sponsor
- Astana Medical University
Covid-19, Viral Infection
Dissemination of SARS-COV-2 (COVID-19) in the Environment of Infected Patients Admitted to Intensive Care Unit
The objective of this protocol is to estimate the proportion of patients hospitalized in intensive care unit for a SARS-Cov-2 viral lung infection and contaminating their environment at 1 meter.
- Trial name
- ENVIROREA (NCT04355481)
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety, Depression
Improving Mental Health Among the LGBTQ+ Community
The overall aim of this program of research is to improve the mental health of people who identify as LGBTQ+ by increasing their social support through a brief intervention.
- Trial name
- NCT05540067
- Testing
- Acceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Brown University
COVID - 19
Early-stage Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19
This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19. It will also learn about the safety of drug Ratutrelvir.
- Trial name
- NCT07157007
- Testing
- Ratutrelvir (83-0060) non-randomised, Paxlovid, Ratutrelvir (83-0060)
- Where
- 15 sites in Australia, South Korea and 2 more
- Volunteers
- 90 people
- Sponsor
- Traws Pharma, Inc.
Vaccination Refusal
Effectiveness of a Mayan Language Social Media Campaign on COVID-19 Vaccine Beliefs in Guatemala
Prior evidence, including formative work supporting the development of this study, suggests there is widespread vaccine hesitancy among Indigenous communities in Guatemala, fueled by mistrust in the health system, lack of…
- Trial name
- NCT05252936
- Testing
- COVID-19 vaccine social media campaign exposure
- Where
- Guatemala
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Stanford University
Bone Loss
Impact of COVID-19 on Sinus Augmentation Surgery
The risk of Schneiderian membrane perforation and the postoperative complications of the sinus floor elevation surgery were evaluated for patients with and without history of COVID-19 infection.
- Trial name
- NCT05960136
- Testing
- Sinus lift in patients with positive COVID-19 history, Sinus lift with negative COVID-19 history
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
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