Clinical trials: SARS-COV-2 Infections
SARS CoV 2 Infection
Study to Evaluate Safety, Tolerability, Efficacy and Pharmacokinetics of ASC10 in Mild to Moderate COVID-19 Patients
This is a phase Ib, randomized, double-blind, placebo-controlled study to evaluate safety, tolerability, efficacy and pharmacokinetics of ASC10 tablets in mild or moderate COVID-19 subjects.
- Trial name
- NCT05596045
- Testing
- ASC10
- Where
- 2 sites in United States
- Sponsor
- Ascletis Pharmaceuticals Co., Ltd.
COVID-19
Atovaquone for Treatment of COVID-19
The purpose of the current study is to accelerate the use of a clinically available therapeutic already FDA-approved for other indications in the setting of pandemic COVID-19 addressing a serious and emergent unmet medical need.
- Trial name
- NCT04456153
- Testing
- Experimental Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
COVID-19 Infection
Immunosupressive Treatment in COVID-19 Patients
SAM-COVID is a retrospective cohort study that aims to determine the impact of immunosuppressive drugs and immunoglubulins in the outcome of patients with COVID-19.
- Trial name
- SAM-COVID (NCT04382781)
- Testing
- NO-Immunosuppressive, Immunosuppressive, Immunoglubulins
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Spanish Network for Research in Infectious Diseases
Coronavirus Disease 2019
Autoimmunity Contributes to the Severe Progression of COVID-19
Although elderliness and chronic comorbidities such as hypertension, diabetes, cardiovascular diseases and respiratory diseases, are known risk factors for severe progression of COVID-19, it still remains puzzling on why younger…
- Trial name
- NCT04967781
- Testing
- autoimmunity
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhongnan Hospital
Knowledge, Attitudes, Practice
Capacity Building and Service Enhancement in Integrated Home Care Services
As people live longer lives, the ageing population causes an unprecedented rise in healthcare and social services demand. Limited studies were to evaluate the effectiveness of risk management measures of home care service and the…
- Trial name
- NCT05192096
- Testing
- Train-the-trainer workshop
- Where
- Hong Kong
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Covid19
BCG Against Covid-19 for Prevention and Amelioration of Severity Trial (BAC to the PAST)
The purpose of this study is to assess the efficacy of Bacille Calmette-Guérin (BCG) vaccination compared to placebo in reducing severe Covid-19 disease among elderly residents of skilled nursing facilities.
- Trial name
- NCT04534803
- Testing
- BCG Vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Post-COVID-19
Changes in Selected Function- and Participation-related Characteristics in Post-COVID Patients Following Pneumological Phase II Rehabilitation
The aim of this project is to provide insight into the relatively new group of post-COVID patients. On the basis of data collected in routine practice, function- and participation-related patient characteristics of post-COVID…
- Trial name
- NCT05496842
- Testing
- Multimodal pulmonary rehabilitation
- Where
- Austria
- Volunteers
- 779 people
- Sponsor
- Pensionsversicherungsanstalt
Covid19, Corona Virus Infection
Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients
The purpose of this study to evaluate the translational application of the safe and effective treatment of Narrow-Band Ultraviolet light B-band (NB-UVB) to high-risk COVID-19 patients in an effort to improve their immune and…
- Conditions
- Covid19, Corona Virus Infection, Autoimmune Diseases, Coagulation Disorder, Blood
- Trial name
- NCT04818970
- Testing
- Narrow Band ultraviolet B-Band Light, non Narrow Band ultraviolet B-Band Light
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cytokind, Inc.
Spinal Cord Injuries
Needs of Persons with Spinal Cord Injury (SCI)
Persons with spinal cord injury (PwSCI) are at a greater risk for major health conditions and poorer health outcomes than persons without spinal cord injury (SCI).
- Trial name
- NCT04422769
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Washington University School of Medicine
Graves Disease
Incidence of Graves' Disease After COVID-19 Vaccination
It is well known that an infection can be a triggering factor for the development of autoimmune thyroid disease. The COVID-19 pandemic was an example of this, with several reports of both subacute thyroiditis as well as Graves'…
- Trial name
- NCT07213141
- Testing
- Data extraction
- Where
- 3 sites in Belgium
- Volunteers
- 161 people
- Sponsor
- Laura ICONARU
COVID-19
Influence of Nutritional Indices on the Prognosis of Patients With SARS-CoV-2 Infection
With the decline of virulence after the mutation of the SARS-CoV-2 , based on the national life and health and national development needs, the domestic SARS-CoV-2 infection epidemic prevention policy has changed, and the number…
- Trial name
- NCT05835102
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Juan Kang
Coronavirus Infection, Pneumonia, Viral
Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for COVID-19 Pneumonia (COVIDOC Trial)
Double blinded randomized clinical trial designed to evaluate the efficacy and safety of hydroxychloroquine combined with azithromycin compared to hydroxychloroquine monotherapy in patients hospitalized with confirmed COVID-19…
- Trial name
- COVIDOC (NCT04345861)
- Testing
- hydroxychloroquine + azithromycin
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Montpellier
COVID-19 Pandemic
Prospective Study on COVID -19 Reinfection on Vaccinated and Non-vaccinated Outpatients
the aim of the study is to compare the severity of symptoms in case of reinfection with COVID-19. the study will compare between two groups; vaccinated and non vaccinated.
- Trial name
- NCT06544369
- Testing
- COVID-19 vaccin
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Soad Ali
Covid19
Long-term Effects of COVID-19: a Comparative Cohort Study
This study is a longitudinal cohort study which investigates the effect of COVID-19 in ambulatory care. This study aims to assess the effect of COVID-19 beyond the acute phase, i.e.
- Trial name
- CoCo (NCT05002205)
- Testing
- Questionnaires, spirometry, ECG
- Volunteers
- 180 people
- Sponsor
- KU Leuven
Volunteers From the Institute Curie and Institute Pasteur Staff Who Are Not Showing Active SARS-CoV-2 Infection
COVID-19 Study of the Serological Response Against the Severe Acute Respiratory Syndrome (SARS) Coronavirus 2 (CoV-2) Virus in 2 Types of Employees, Hospital and Non-hospital, at Institute Curie and Institute Pasteur
This research proposes to study a large healthy population active for the presence of antibodies directed against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus and this over time.
- Trial name
- Curie-O-SA (NCT04369066)
- Testing
- Blood samples (collection of 5 mL of blood in a dry tube), Nasopharyngeal swabs
- Where
- 2 sites in France
- Volunteers
- 1,971 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Fibromyalgia, Primary
Fibromyalgia During the COVID-19 Pandemic
On 12 January 2020, the World Health Organization (WHO) confirmed that a novel coronavirus was the cause of a respiratory illness in a cluster of people in Wuhan City, Hubei Province, China, which was reported to the WHO on 31…
- Trial name
- NCT04422522
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Al-Azhar University
COVID-19, SARS-CoV-2 Infection
A Study to Evaluate the Immunogenicity and Safety of SCTV01C and SCTV01E (Two Recombinant Protein COVID-19 Vaccines) in Population Aged ≥12 Years
The objective of the study is to evaluate the immunogenicity and safety of SCTV01C or SCTV01E, comparing the immunogenicity data against Beta (B.1.351), Delta (B.1.617.2), Omicron (B.1.1.529) and other variants with Sinopharm…
- Trial name
- NCT05308602
- Testing
- SCTV01C, SCTV01E, mRNA vaccine manufactured by Pfizer or Moderna
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Irritation/Irritant, ICD - Irritant Contact Dermatitis
The Effects of Repeated Exposure to Antiseptics During COVID-19 Pandemic on Skin Parameters
The global coronavirus disease pandemic (COVID-19) has led to an increased need to wear protective equipment such as wearing face masks and practicing hygiene measures such as more frequent use of antiseptics.
- Conditions
- Irritation/Irritant, ICD - Irritant Contact Dermatitis, Antiseptic
- Trial name
- NCT05276102
- Testing
- Emollient cream
- Where
- Croatia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Covid19
Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19)
Background - A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in December 2019 as the cause of a respiratory illness COVID-19 in Wuhan City, China.
- Trial name
- NCT04596839
- Testing
- Remdesivir, Standard of Care
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Dr. Md. Alimur Reza
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