Clinical trials: SARS-COV-2 Infections
Preference, Patient
Preferences of Vaccination for COVID-19 Among University Students and Staff: A Discrete Choice Experiment
From March 2021, COVID-19 vaccines have been made available to Hong Kong residents, first to priority groups including healthcare professionals and the elderly, and later to all adults and adolescents.
- Trial name
- NCT05150769
- Where
- Hong Kong
- Volunteers
- 3,423 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Coronavirus Infection
Characteristics in Post Covid-19 Patients
To evaluate pulmonary changes and the results of a cardiopulmonary rehabilitation protocol (CPRP) in patients after SARS-VOC-2 infection.
- Trial name
- NCT04514705
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Covid19, Hospitalization
Intensive Dose Tinzaparin in Hospitalized COVID-19 Patients
The primary objective of this study is to evaluate the current management approach with "intermediate" or "therapeutic" doses of tinzaparin for thromboprophylaxis in hospitalized patients, non on ICU organ support, with confirmed…
- Trial name
- INTERACT (NCT05036824)
- Testing
- tinzaparin
- Where
- 7 sites in Greece
- Volunteers
- 300 people
- Sponsor
- University Hospital of Patras
COVID-19 Vaccines, Hemodialysis Complication
Response of Haemodialysis Patients to BNT162b2 mRNA Cov-19 Vaccine
Vaccination against SARS-Cov2 is a necessity for haemodialysis patients because difficulties to maintain a self-isolation (leading to a higher contamination than general population) and an increase of mortality in case of…
- Trial name
- ROMANOV (NCT04881396)
- Testing
- Evaluation of the immunogenicity of the vaccine in haemodialysis patients
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV2 Infection
TekiTrust Tests to Determine the Level of SARS-COV-2/COVID-19 Neutralizing Antibodies in the Blood
The purpose of this study is to determine if the TekiTrust Enzyme-Linked Immunosorbent Assay (ELISA) Kit and TekiTrust Rapid Test can accurately determine the amount of antibodies to fight the COVID-19 virus in sampled blood…
- Trial name
- NCT05338762
- Where
- 5 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- MiCo BioMed Co., Ltd.
Respiratory Distress Syndrome, Adult, COVID-19
Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT
We aims to investigate the effects of prone positioning and nitric oxide inhalation in adult patients who is diagnosed with COVID-19 associated acute respiratory distress syndrome by electrical impedance tomography.
- Trial name
- NCT05715762
- Testing
- prone postion, NO inhalation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
COVID-19
Convalescent Plasma in COVID-19 Elderly Patients
The trend of the spread of the COVID-19 pandemic demonstrates in Lombardy, starting from 28.03.2020, a slowdown in the exponential phase of infections and the probable reaching of a plateau phase.
- Trial name
- RESCUE (NCT04569188)
- Testing
- Convalescent plasma
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Mantova
COVID-19
Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19
This is Phase 2 multi-center controlled randomized study to assess the efficacy and safety of MIR 19® via 14 days of treatment of participants with symptomatic moderate COVID-19.
- Trial name
- NCT05184127
- Testing
- MIR 19 ®, Standard COVID-19 therapy
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
CORONAVIRUS INFECTIONS
Effect of a Vaccination Against COVID-19 on Monocyte Production of Oxygenated Derivatives.
Knowing that the vaccine antigen includes the ACE2 binding moiety (RBD), the hypothesis is that circulating vaccine antigen could reduce the enzymatic activity of ACE2, and thus increase circulating AngII concentration, monocyte…
- Trial name
- VACTICOV2 (NCT05655351)
- Testing
- anti-SARS-Cov-2 vaccination
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Covid19
Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved Population
The primary goal of this study is to determine the most effective SARS-CoV-2 testing strategy for successful return of in-person school in the under-served communities of St. Louis.
- Trial name
- NCT04875520
- Testing
- Screening testing strategy, No screening testing strategy
- Where
- 5 sites in United States
- Volunteers
- 1,390 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
SARS-CoV Infection
Oral Manifestation in Patients With SARS-CoV2 Infection.
The oral cavity is particularly susceptible to viral infection with several viruses such as herpes simplex virus, cytomegalovirus and Zika virus because of its structures, especially salivary glands and soft tissues Moreover…
- Trial name
- NCT04821986
- Where
- Egypt
- Volunteers
- 583 people
- Sponsor
- Fayoum University
COVID-19 Pandemic, Vitamin D Deficiency
COVID-19 and Vitamin D: Length of Hospital Stay and Mortality
The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition.
- Trial name
- NCT05221983
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Yuksek Ihtisas University
Respiratory Distress Syndrome, Adult, Sars-CoV2
Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS
Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of ~40%, and has no known treatment other than optimization of support.
- Trial name
- CHILL-pilot (NCT03376854)
- Testing
- Hypothermia, Neuromuscular Blocking Agents, Standard of Care
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.
- Conditions
- COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle, Remodeling, Vascular, Left Ventricular Dysfunction
- Trial name
- MYOFLAME-19 (NCT05619653)
- Testing
- Prednisolone, Losartan
- Where
- 5 sites in Austria, Germany
- Volunteers
- 279 people
- Sponsor
- Valentina Puentmann
Covid19
Performance Evaluation of LumiraDx COVID-19 (SARS-CoV-2) Ag Test
Performance of the LumiraDx SARS-CoV-2 Ag assay will be assessed by comparison to a reference method.
- Trial name
- ASPIRE (NCT04557046)
- Testing
- Nasal Swab, Nasopharyngeal swab, Throat swab
- Where
- 7 sites in United States
- Volunteers
- 1,134 people
- Sponsor
- LumiraDx UK Limited
Covid19
Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection
In the context of the actual pandemia of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which requires a better diagnostic strategy for the management of patients.
- Trial name
- VOC-COVID-Diag (NCT04614883)
- Testing
- Volatile Organic Compounds analysis, Canine odor detection of Volatile Organic Compounds
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Hopital Foch
Ventilator Associated Pneumonia, Covid19
Incidence of VAP in Patients With Severe COVID-19
Combined retrospective and prospective cohort study to evaluate the incidence of microbiologically confirmed VAP in mechanically ventilated patients with COVID-19.
- Trial name
- CoV-AP (NCT04766983)
- Testing
- bronchoalveolar lavage
- Where
- Italy
- Volunteers
- 323 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Sars-CoV-2 Infection
Impact of Genetic Polymorphisms of Vasoactive Peptides on the Prognosis of Patients With COVID19
Introduction: A pandemic such as the SRAS-CoV-2 (COVID-19) has a great negative socioeconomic impact with very limited therapeutic options.
- Trial name
- NCT05160779
- Testing
- Analysis of genetic polymorphisms of vasoactive peptides in COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 151 people
- Sponsor
- Leonardo Paroche de Matos
Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections
Overcoming Geography With Technology: Medical Drones Project
In this study, the investigators shall evaluate the use unmanned air vehicles (medical drones) to deliver ART to adult patients eligible/enrolled in community DSD models in Bufumira Islands, Kalangala district.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections, COVID-19
- Trial name
- NCT05259761
- Testing
- Unmanned ariel vehicle
- Where
- Uganda
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Makerere University
COVID-19
Wearable Diagnostic for Detection of COVID-19 Infection
The goals of this study are 1) to validate the use of a wearable diagnostic capability and software as a medical device (SaMD) algorithm for the pre or early-symptomatic detection of COVID-19 infection, 2) assess the wearable…
- Trial name
- NCT04742569
- Where
- United States
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- ClinOne, Inc.
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