Clinical trials: SARS-COV-2 Infections
Depression, Burnout, Professional
Health cAre woRkers exposeD to COVID-19
Health care workers working in hospital or nursing home for elderly people involved in the coronavirus epidemic are facing several challenges such as direct exposure and involvement in the resolution of major public health…
- Conditions
- Depression, Burnout, Professional, Post Traumatic Stress Disorder
- Trial name
- HARD-COVID19 (NCT04570202)
- Testing
- EMDR
- Where
- 2 sites in France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Tours
COVID
Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care (LUS-COVID19)
It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable…
- Trial name
- LUS-COVID19 (NCT04393402)
- Testing
- lung ultrasound (LUS)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
SARS-CoV2, Breastmilk
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a
The Canadian Paediatric Society recommends breastfeeding during COVID-19 infection. Human milk is the best form of infant nutrition providing significant protection against many illnesses for term and preterm infants.
- Trial name
- NCT04453969
- Testing
- COVID-19
- Where
- 2 sites in Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Deborah O'Connor
COVID-19 Acute Respiratory Distress Syndrome
Effects of Exercise on the Renin-angiotensin System
Angiotensin converting enzyme-2 (ACE2) is part of the renin-angiotensin system (RAS), which is involved in maintaining blood flow and electrolyte balance.
- Trial name
- NCT05115383
- Testing
- VO2 Max test
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
COVID-19 Severe Pneumonia, Acute Lung Injury
Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia
This study evaluated the efficacy, safety, pharmacokinetics, and pharmacodynamics of ravulizumab administered in adult participants with coronavirus disease 2019 (COVID-19) severe pneumonia, acute lung injury, or acute…
- Conditions
- COVID-19 Severe Pneumonia, Acute Lung Injury, Acute Respiratory Distress Syndrome, Pneumonia, Viral
- Trial name
- NCT04369469
- Testing
- Ravulizumab, BSC
- Where
- 39 sites in United States, France and 3 more
- Volunteers
- 202 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Covid19
AGILE (Early Phase Platform Trial for COVID-19)
The AGILE platform master protocol allows incorporation of a range of identified and yet-to-be-identified candidates as potential treatments for adults with COVID-19 into the trial.
- Trial name
- AGILE (NCT04746183)
- Testing
- CST-2: EIDD-2801, Nitazoxanide, VIR-7832
- Where
- 7 sites in South Africa, United Kingdom
- Volunteers
- 600 people
- Sponsor
- University of Liverpool
Low Back Pain
Low Back Pain in Mothers of Children With Disabilities
This is a cross-sectional study that aims to determine the prevalence of low back pain in mothers of children with disabilities following the COVID-19 pandemic and to describe its relationship with exposure to the virus, handgrip…
- Trial name
- NCT07106905
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Selvin BALKİ
Post-Covid Syndrome
Residual Symptoms After Coronavirus Disease (COVID-19) in Lithuanian Population
The aim of the study is to describe the post-covid-19 syndrome in Lithuanian population regarding the remaining symptoms and their impact on physical functioning, work ability and needs of rehabilitation.
- Trial name
- Post-Covid (NCT05000229)
- Where
- Lithuania
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Covid19, Interstitial Pneumonia
Identification of Predictors for the Evolution of COVID-19 Related Pneumonia by Transcriptomic and Seroproteomic
The investigating group aims at performing an observational, prospective study that involves the evaluation of circulating biomarkers predictive of clinical evolution in patients suffering from COVID-19 disease.
- Trial name
- COVID_OMICS (NCT04441502)
- Where
- Italy
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Pneumonia, Viral, Corona Virus Infection
Convalescent Antibodies Infusion in COVID 19 Patients
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04418531
- Testing
- Anti-coronavirus antibodies (immunoglobulins) obtained with DFPP form convalescent patients
- Sponsor
- Piero Luigi Ruggenenti
Covid19, Cardiopulmonary Disease
Physiological Studies in Post-COVID-19 Syndrome, and the Association With DNA Methylation
The physiological derangements in subjects suffering from long-term symptoms following a Covid-19 infection (Post-COVID-19 Syndrome) are poorly understood and evaluated.
- Conditions
- Covid19, Cardiopulmonary Disease, Dyspnea, Lung Function Decreased
- Trial name
- NCT04859894
- Testing
- Physiological testing
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
New Coronavirus Disease (COVID-19), Infection With SARS-CoV-2
Study of Immune Response During SARS-CoV-2 Infection - (COVID-19)
Study of the cellular immune response during the SARS-CoV-2 infection and identify cytokinic profiles in caregivers exposed to the virus with asymptomatic forms of COVID19, patients with an asymptomatic form followed in…
- Trial name
- CovImmune (NCT04355351)
- Testing
- blood sampling, additional blood tubes
- Where
- 3 sites in France
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Covid19
Endoscopic Procedures of Children in the Normalization Process of Covid-19 Pandemic
Endoscopic methods are frequently used in the diagnosis of gastrointestinal system pathologies in children.
- Trial name
- NCT04598256
- Testing
- Endoscopic procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Tepecik Training and Research Hospital
Dysfunctional Worry
A Online-delivered Cognitive-behavioral Intervention for Dysfunctional Worry Related to the Covid-19 Pandemic
The purpose of this study is to investigate if a brief online-delivered cognitive-behavioral intervention can reduce the degree of dysfunctional worry related to the Covid-19 pandemic, compared to a wait-list control condition.
- Trial name
- NCT04341922
- Testing
- Internet-delivered cognitive behavior therapy (ICBT) for dysfunctional worry related to the Covid-19 pandemic
- Where
- Sweden
- Volunteers
- 670 people
- Sponsor
- Karolinska Institutet
COVID-19
GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects
The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetics of GS-441524 in healthy subjects. The main questions to answer are: 1) What dosage of GS-441524 is required for adequate therapeutic…
- Trial name
- NCT06274853
- Testing
- GS-441524
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Advancing Translational Sciences (NCATS)
Sars-CoV2, COVID-19
Home Pulse Oximeter Use in Patients With COVID-19
The purpose of this study is to investigate the use of home pulse oximetry monitoring in patients with COVID-19 to trend disease progression and identify need for hospitalization.
- Conditions
- Sars-CoV2, COVID-19, COVID
- Trial name
- NCT04373161
- Testing
- Home Pulse Oximetry Monitoring
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Swedish Hospital
COVID-19 Respiratory Infection, COVID-19
Efficacy and Safety Study of Essential Oil-Based Preparation Administered to COVID-19 Patients
The aim of this study was to compare the efficacy and safety of the essential oil-based product in patients with mild to moderate symptomatic COVID-19 Positive infection confirmed by PCR.
- Trial name
- NCT06452069
- Testing
- IMMUNO19
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Biodex S.A
Sepsis, Sepsis Bacterial
Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis
This observational cohort study aims to compare clinical outcomes and inflammatory responses between patients with viral sepsis, specifically COVID-19-associated sepsis, and those with bacterial sepsis.
- Conditions
- Sepsis, Sepsis Bacterial, Viral Sepsis, Inflammatory Response
- Trial name
- NCT06491966
- Testing
- observation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sichuan Provincial People's Hospital
Pulmonary Embolism
Registry of the Evolution of Diagnosed and/or Hospitalized Patients for Pulmonary Embolism During the Covid-19 Pandemic
The purpose of the study COVID-EP is to classify all the complications occurring after the diagnosis of pulmonary embolism in patients tested initially COVID-19 positive and negative by RT-PCR (on nasopharyngeal sample) during…
- Trial name
- COVID-EP (NCT04465656)
- Testing
- Serology test for COVID-19
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Long COVID, Post-Acute Sequelae of SARS-CoV-2 Infection
Long COVID Diagnostic Reactivity Assesment Test
This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing.
- Trial name
- EAV-LONGCOVID (NCT07343856)
- Testing
- Electrodiagnostic Bioelectrical Assessment
- Where
- Uzbekistan
- Volunteers
- 50 people
- Sponsor
- Oncology Center,Ministry Of Heath,Uzbekistan
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