Clinical trials: SARS-COV-2 Infections
Stress, Psychological, Child Behavior
Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19
The investigators aim to deliver a tele-wellness supported app to Baltimore City's Family Child Care Home (FCCH) providers who are caring for children of Essential Personnel.
- Conditions
- Stress, Psychological, Child Behavior, Social Competence
- Trial name
- NCT04453657
- Testing
- FamilyChildCare (provisional name of app)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COVID-19, Vaccine Reaction
Investigating COVID-19 Vaccine Immunity in Children in the Melbourne Infant Study of BCG for Allergy and Infection Reduction
The COSI BAIR trial will involve approximately 60 children, aged 5 to 8 years old, comprising a subset of participants from the Melbourne Infant Study BCG for Allergy and Infection Reduction (MIS BAIR) randomised controlled…
- Conditions
- COVID-19, Vaccine Reaction, Immunization; Infection
- Trial name
- COSI BAIR (NCT05168709)
- Testing
- Tozinameran
- Where
- Australia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Covid19
The Role of CT Chest Scan in the Pre-anesthetic Assessment of Suspected or Confirmed COVID -19 Patients
The role of CT scan of the chest in Pre-anesthetic assessment of the severity of COVID-19 and the correlations between CT measurements of the aortic and pulmonary arteries diameters and severity of pneumonia.
- Trial name
- NCT04560530
- Testing
- Non-enhanced CT scan of the chest
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Tanta University
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
SARS-CoV 2, Neurologic Manifestations
COVID19 Neurological Manifestation
This study is a prospective observational cohort study to document the prevalence and types of neurological manifestations among hospitalized patients with confirmed or suspected novel coronavirus infection (COVID-19).
- Trial name
- NCT04496128
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
COVID-19
Efficacy and Safety of JT001 (VV116) Compared With Paxlovid
The purpose of this study is to evaluate the efficacy and safety of JT001 (VV116) Compared With Paxlovid for the Treatment of Coronavirus Disease 2019 (COVID-19) in Participants With Mild to Moderate COVID-19.
- Trial name
- NCT05341609
- Testing
- JT001, Paxlovid
- Where
- 7 sites in China
- Volunteers
- 822 people
- Sponsor
- Vigonvita Life Sciences
Covid-19
Mesenchymal Stem Cell Therapy for SARS-CoV-2-related Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is the major cause of death in the COVID-19 pandemic. In this trial, the safety and efficacy of Mesenchymal Stem Cells (MSC) for the treatment of ARDS in COVID-19 patients will be…
- Trial name
- NCT04366063
- Testing
- Cell therapy protocol 1, Cell therapy protocol 2
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Acute Lung Injury, Acute Kidney Injury
Safety and Efficacy Evaluation of CO2 Removal in Combination With Continuous Veno-Venous Hemodialysis/Hemodiafiltration Therapy
Objective of the study is to assess the safety and efficacy of CO2 removal by the multiECCO2R (CO2 Removal System) on the multiFiltrate/multiFiltrate Pro in veno-venous extracorporeal circulation during continuous renal…
- Conditions
- Acute Lung Injury, Acute Kidney Injury, Hypercapnia, Covid19
- Trial name
- multiECCO2R (NCT04871893)
- Testing
- multiECCO2R blood-gas exchanger
- Where
- 6 sites in Germany
- Volunteers
- 28 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Cancer, Immunotherapy
Retrospective Study of COVID-19 Vaccines in Patients Undergoing Immunotherapy for Cancer.
The investigators wish to set up a pharmaco-epidemiological cohort within the Hospital Territorial Groups of the Cévennes-Gard Camargue, East-Hérault and Haute-Garonne and West Tarn on a specific population, patients undergoing…
- Trial name
- IVACOV (NCT05025514)
- Where
- 5 sites in France
- Volunteers
- 125 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Covid-19
Antioxidant Therapy for COVID-19 Study
Finding effective strategies to treat or prevent the novel coronavirus disease that started in 2019 (COVID-19) is a global public health priority.
- Trial name
- GSHSOD-COVID (NCT04466657)
- Testing
- Antioxidation Therapy, Standard of Care
- Where
- 11 sites in Nigeria
- Sponsor
- Obafemi Awolowo University
COVID-19
Sodium Pyruvate Nasal Spray Treatment of COVID-19 Infection
Cellular Sciences Inc has submitted over 17 human clinicals (phase I, II, III including animal safety data) to the FDA for the reduction of respiratory inflammation and inflammatory cytokines including IL-6 the cause of the…
- Trial name
- NCT04824365
- Testing
- Sodium Pyruvate, Saline
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Cellular Sciences, inc.
Rheumatism
Assessment of the Psychological Impact of the COVID19 (SARS-CoV-2) Pandemic on Patients With Chronic Inflammatory Rheumatism
Patients with chronic inflammatory rheumatism (RIC) or autoimmune diseases, rheumatoid arthritis and spondyloarthritis, are regularly monitored in consultation as part of a "treat to target" strategy with rapid adaptation of…
- Trial name
- RICOVID19 (NCT04723407)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 950 people
- Sponsor
- University Hospital, Limoges
Type2 Diabetes
Stories for Change: Digital Storytelling Intervention for Diabetes Self-Management in the COVID-19 Pandemic
Hispanic adults are twice as likely to have type 2 diabetes mellitus (T2D) and 1.5 times more likely to die from the disease than non-Hispanic whites.
- Trial name
- S4C - COVID-19 (NCT04738032)
- Testing
- Digital Storytelling Intervention
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Mayo Clinic
Hemiplegia, Muscle Spasticity
Tele-physiotherapy on Post-stroke Hemiplegia Patients
The present preliminary randomized trial will be performed to compare the effectiveness of telephyisiotherapy plus physical exercises versus other conventional techniques (electromyographic biofeedback or conventional…
- Trial name
- NCT06048432
- Testing
- Conventional Physiotherapy + telephysiotherapty
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Covid19, Vitamin D
Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19
Open controlled clinical trial. Hospitalized pediatric patients with COVID-19 will be included. Upon admission to hospital serum determination of vitamin D, interleukins, ferritin and Dimer D will be performed.
- Conditions
- Covid19, Vitamin D, Children, Only
- Trial name
- COVID-19 (NCT04502667)
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Pregnancy Complications, Covid19
Lung Ultrasound Signs and Patterns in COVID-19 Pregnant Women
SARS-CoV-2 impact on pregnant women is not well known yet. Some authors demonstrated that lung ultrasound can give similar results if compared to chest computed tomography and better results if compared to chest x-rays without…
- Trial name
- PINK-CO (NCT04823234)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
COVID-19
A Study to Evaluate OP-101 (Dendrimer N-acetyl-cysteine) in Severe Coronavirus Disease 2019 (COVID-19) Patients
The primary purpose of Stage-I of this study is to evaluate the safety and tolerability of OP-101 in patients with severe COVID-19 and of Stage 2 of this study is to evaluate the efficacy of OP-101 in patients with severe…
- Trial name
- PRANA (NCT04458298)
- Testing
- OP-101
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Ashvattha Therapeutics, Inc.
COVID-19 Pneumonia
Tele-rehabilitation Program After Hospitalization for COVID-19
Given the number of hospitalized subjects for COVID-19, the difficulties linked to the infectious risk, and the high cost of managing departments for COVID-19 subjects, the execution of home rehabilitation programs, in the form…
- Trial name
- NCT04821934
- Testing
- TR, TSu
- Where
- 2 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COVID19, Coronavirus Infection
Convalescent Plasma Collection and Treatment in Pediatrics and Adults
This is a prospective study, using plasma to help fight off infections of those suffering from COVID-19 in accordance with collection guidelines for plasma and FDA IND requirements.
- Conditions
- COVID19, Coronavirus Infection, Coronavirus, Virus Diseases
- Trial name
- NCT04376034
- Testing
- Convalescent Plasma
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- West Virginia University
Severe COVID-19 Disease
Study on the Safety and Efficacy of Convalescent Plasma in Patients With Severe COVID-19 Disease
Currently, there is no specific treatment or vaccine for SARS-CoV-2 available, some drugs are being investigated as treatment, but the effect is unknown.
- Trial name
- PC-COVID-HCM (NCT04542967)
- Testing
- Biological
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Hospital Central Militar
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