Clinical trials: SARS-COV2 Infection
Endoscopy
Evaluation of Transnasal Endoscopy During COVID-19 Pandemic
Patients who received the indication for endoscopic diagnostics using gastroscopy in transnasal technique will be included into the study. The examination is carried out in standard technique and is not influenced by the study.
- Trial name
- NCT04734912
- Testing
- gastroscopy in transnasal techique
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
2019 Novel Coronavirus
The Potential Use of Inhaled Hydroxychloroquine for the Treatment of COVID-19 in Cancer Patients
This is a pilot, randomized, single-center, parallel group, open-label controlled study to evaluate the feasibility, safety, efficacy, and pharmacokinetics of nebulized HCQ01 plus Standard of Care (SOC) versus SOC alone in…
- Trial name
- NCT04731051
- Testing
- HCQ01, standard of care (SOC) for COVID-19
- Where
- Jordan
- Sponsor
- King Hussein Cancer Center
COVID-19
Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients
This open label, randomized, controlled, investigator-initiated, multi-centre trial aims to establish metabolic improvements in COVID-19 subjects by dietary supplementation with cofactors N-acetylcysteine, L-carnitine tartrate…
- Trial name
- NCT04573153
- Testing
- Hydroxychloroquine + Metabolic cofactor supplementation, Hydroxychloroquine + Sorbitol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- ScandiBio Therapeutics AB
History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection
ACE Inhibitors or ARBs Discontinuation in Context of COVID-19 Pandemic
Since December 2019, a novel coronavirus called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has caused an international outbreak of respiratory illness described as COVID-19.
- Trial name
- ACORES-2 (NCT04329195)
- Testing
- 1: discontinuation of RAS blocker therapy, 2: continuation of RAS blocker therapy
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Attitude and Perception Towards COVID-19 Pandemic
Assess response and attitude of general population living in Sharkia Governerate, Egypt as regard COVID-19 pandemic through arabic questionnaire.
- Trial name
- NCT04400812
- Testing
- questionnaire
- Where
- Egypt
- Volunteers
- 5,000 people
- Sponsor
- Zagazig University
Respiratory Syncytial Virus Infections
A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above
This study is assessing the immunogenicity, safety and reactogenicity of the RSVPreF3 OA investigational vaccine when it is co-administered with a COVID-19 messenger ribonucleic acid (mRNA) vaccine (Omicron XBB.1.5), compared to…
- Trial name
- NCT06374394
- Testing
- RSVPreF3 OA investigational vaccine, COVID-19 mRNA vaccine
- Where
- 24 sites in United States, Belgium and 2 more
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid19
Phase IIb Trial of Recombinant Novel Coronavirus Vaccine (Ad5-nCoV) in Adults 18 Years of Age and Older, Living With HIV
A randomized, double-blind, placebo -controlled, phase IIb clinical trial to evaluate the efficacy, safety and immunogenicity of one or two doses of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in adults 18…
- Trial name
- COVID-19 (NCT05005156)
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (Ad5-nCoV)
- Where
- 4 sites in Argentina
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Fundación Huésped
COVID-19
Efficacy of Breathox Device Inhalation Therapy in the Treatment of Acute Symptoms Associated With COVID-19 and in the Prevention of the Use of Health Resources
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the new coronavirus, causes a disease called COVID-19 that can trigger aggressive inflammatory responses.
- Trial name
- BREATH (NCT05196581)
- Testing
- Dispersible NaCl powder 10 sessions, Dispersible NaCl powder 5 sessions
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzana Erico Tanni Minamoto
COVID-19
Relation Between COVID-19 Pts and Hyponatremia in Adreno Ortical Insufficient Patients.
Hyponatremia in COVID-19 patients with adrenal insufficiency
- Trial name
- NCT05408481
- Testing
- Serum cortisol level
- Volunteers
- 50 people
- Sponsor
- Assiut University
COVID-19
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19
The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19.
- Trial name
- NCT04411628
- Testing
- LY3819253
- Where
- 11 sites in United States
- Volunteers
- 26 people
- Sponsor
- Eli Lilly and Company
Covid19
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Neutralizing Antibody in Healthy Participants
The primary purpose of this study is to investigate the safety and tolerability of BGB-DXP593 administered intravenously as a single dose in healthy participants
- Trial name
- NCT04532294
- Testing
- BGB DXP593
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- BeiGene
Covid19
Is Bio-adrenomedullin (Bio-ADM) a Prognostic Factor in Patients With COVID-19 Treated in the ICU?
This is prospective, observational study using point of care test to determine bio-ADM whole blood concentrations and its predictive value in patients with COVID-19 treated in the ICU.
- Trial name
- NCT04813939
- Testing
- IB10 sphingotest® bio-ADM® apparatus (Sphingotec GmbH, Hennigsdorf, Germany)
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Warsaw
COVID-19, Sport Performance, Professional Overhead Athletes
Effect of COVID-19 Infection on the Performance of Adolescent Professional Overhead Athletes
COVID-19 is known to also cause damage outside the pulmonary system, particularly the cardiovascular and the musculoskeletal system.
- Trial name
- Atılım Unv (NCT05298839)
- Testing
- Evaluation of core muscle endurance, hand grip strength, upper extremity functional performance, reaction time, agility performance and 3 minutes step test
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Atılım University
Lung Cancer, Covid19
Anti-SARS-COV2 Vaccination Study in Lung Cancer Patients
Observational and multicenter retrospective study of data collection in hospital centers throughout the Spanish geography. This study aims to be nationwide in order to study general common variables of the patients, as well as…
- Trial name
- VAC-CaP (NCT05009030)
- Testing
- COVID-19 vaccine
- Where
- 51 sites in Spain
- Volunteers
- 794 people
- Sponsor
- Fundación GECP
Cancer, Immune Checkpoint Inhibitors
COVICI-SURV: COVID-19 Vaccination Around ICI Start and Survival
COVICI-SURV is a nationwide, retrospective observational cohort study using the French national health data system (SNDS) to evaluate whether COVID-19 vaccination, particularly mRNA vaccination, received within 100 days before or…
- Conditions
- Cancer, Immune Checkpoint Inhibitors, COVID-19 Vaccination, Survival
- Trial name
- COVICI-SURV (NCT07729241)
- Where
- France
- Volunteers
- 95,015 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
COVID-19
Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients with Moderate COVID-19
This is a double-blind, multicentre, multinational study to evaluate the safety and collect preliminary efficacy data of Codivir drug product in 130 hospitalized adults with moderate COVID-19 symptoms.
- Trial name
- NCT05218356
- Testing
- Covidir injections, Quantitative PCR SARS-CoV-2, IgM and IgG dosage
- Where
- 5 sites in Brazil
- Volunteers
- 130 people
- Sponsor
- Code Pharma
Covid19
Prospective Clinical and Virological Analysis of Healthcare Workers Diagnosed Positive for Covid-19.
Coronavirus disease 2019 (COVID-19) is an acute infection of the respiratory tract that emerged in late 2019. In several studies, the cardinal signs of COVID-19 associated fever, cough, sputum and dyspnea occurring in the first…
- Trial name
- Pro-Co-HPA (NCT04858581)
- Testing
- Virological and serological tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Covid19
Hematology and Clinical Picture in Pediatric COVID-19 Infection
This study is to discuss the different clinical presentations, hematological and laboratory abnormalities in pediatric COVID-19 infection.
- Trial name
- NCT04487119
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Benha University
COVID-19, Emergency Surgery
Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow
The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing…
- Conditions
- COVID-19, Emergency Surgery, Abdominal Surgery, Real-World Data
- Trial name
- SurgCOVID-Mos (NCT07719166)
- Testing
- Surgical and Interventional Management of Acute Surgical Conditions
- Where
- Russia
- Volunteers
- 58,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Coronavirus, Pneumonia
Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)
There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers.
- Conditions
- Coronavirus, Pneumonia, Oxygen Toxicity
- Trial name
- NCT04320056
- Testing
- Standard administration of oxygen flow, Automated oxygen administration - FreeO2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Laval University
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