Clinical trials: SARS-COV2 Infection
SARS-CoV-2 Infection, Hematologic Malignancy
Mechanism and Immune Function Analysis of SARS-CoV-2 Infection in Hematologic Tumors
The goal of this observational study is to compare the immune function and infection mechanism of patients with hematologic tumors and those people without underlying diseases after infection with SARS-CoV-2.
- Trial name
- NCT05683353
- Testing
- None intervention
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
SARS-CoV-2
Post-marketing Safety of Elasomeran/Davesomeran and Andusomeran
The main objective of the study is to evaluate the safety of the elasomeran/davesomeran and andusomeran vaccines as used in routine clinical practice.
- Trial name
- NCT06130345
- Testing
- SPIKEVAX
- Where
- United States
- Volunteers
- 15,196,685 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19
Homologous vs Heterologous Third Vaccination in Kidney Transplant Recipients Kidney Transplant Recipients
Randomized-controlled trial comparing homologous (mRNA vaccine) vs. heterologous (vector vaccine) for third SARS-CoV-2 vaccine dose in kidney transplant recipients not responding to initial prime-boost vaccination with an mRNA…
- Trial name
- BOOST_TX (NCT05324319)
- Testing
- Ad26COVS1, ChAdOx1 SARS2 Vaccine, BNT162B2
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Covid-19, Hypoxia
Hydrocortisone for COVID-19 and Severe Hypoxia
We aim to assess the benefits and harms of low-dose hydrocortisone in patients with COVID-19 and severe hypoxia.
- Trial name
- COVID STEROID (NCT04348305)
- Testing
- Hydrocortisone, Sodium Chloride 9mg/mL
- Where
- 14 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Scandinavian Critical Care Trials Group
Covid 19
Evaluation of the Clinical Impact of Corticosteroid Duration on SARS-CoV-2 (COVID-19 WHO)
The purpose of this project is to evaluate the clinical impact of the use of glucocorticoids beyond 10 days for patients with critical COVID-19 at MDMC.
- Trial name
- NCT05595031
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Methodist Health System
Covid19
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
Collection of SARS-COV-2 Secretions and Serum for Countermeasure Development (aka ClinSeqSer) is an observational study to understand natural history of SARS-COV-2 infections among special populations and characterise post-covid…
- Trial name
- NCT04956445
- Where
- 2 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tulane University
Olfactory and Taste Dysfunction in SARS-CoV2 Infection
EFFECT OF COVID-19 DISEASE IN SMELL AND TASTE OF PATIENTS WITH MILD, MODERATE OR SEVERE SYMPTOMATOLOGY
This is an observational data and recording study. The aim of our study is to investigate the effect of SARS-COV2 infection on patients' sense of smell and taste, through quality control measurements using optic analogue scale…
- Trial name
- NCT04657445
- Testing
- visual analogue scale
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ioannina
COVID-19, SARS-CoV 2
Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19
Randomized, double-blind, parallel, two-arms clinical trial to assess the efficacy and safety of 2 infusions of Wharton-Jelly mesenchymal stromal cells (day 1 and day 3, endovenously at 1E6cells/Kg per dose) in patients with…
- Conditions
- COVID-19, SARS-CoV 2, Adult Respiratory Distress Syndrome
- Trial name
- COVIDMES (NCT04390139)
- Testing
- XCEL-UMC-BETA
- Where
- 5 sites in Spain
- Volunteers
- 26 people
- Sponsor
- Banc de Sang i Teixits
COVID-19
Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults
This Phase III study will assess whether AZD7442 (a combination of 2 mAbs) can safely treat outpatient adults with COVID-19 and prevent either severe COVID-19 or death.
- Trial name
- TACKLE (NCT04723394)
- Testing
- AZD7442
- Where
- 103 sites in United States, Argentina and 13 more
- Volunteers
- 910 people
- Sponsor
- AstraZeneca
COVID-19
Clinical Study for the Efficacy and Safety of Ropeginterferon Alfa-2b in Adult COVID-19 Patients With Comorbidities
To evaluate the efficacy of subcutaneous ropeginterferon alfa 2b ( P1101 combined with standard of care (SOC) compared with standard care alone in adult COVID-19 patients with comorbidities.
- Trial name
- NCT05808322
- Testing
- Ropeginterferon alfa-2b, SOC
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Covid-19, Subjects Vaccinated Against Covid-19
Change in Antibody Levels Following SARS-CoV-2 (Covid-19) Vaccinations
Limited information is available regarding the effects of various factors that may influence the duration and effectiveness of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) vaccinations. This virus causes Covid-19.
- Trial name
- Covid-19-Abs (NCT04944095)
- Testing
- Change in SARS-CoV-2 Antibody Levels
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Dr. Sidney J. Stohs
Anxiety
Intensive Care Anxiety in SARS-CoV-2 Patients
It should be known by the clinician that COVID-19 patients are prone to anxiety, and these disorders need to be properly diagnosed and addressed to improve prognosis, shorten hospital stay and avoid long-term mental health…
- Trial name
- NCT04715477
- Testing
- Hospital Anxiety Depression Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Derince Training and Research Hospital
Infection Viral
COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults (Dyn3CEA_Nosocor)
Unlike other respiratory viruses such as influenza and Respiratory Syncytial Virus (RSV) where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in…
- Trial name
- NCT04664296
- Testing
- Review of medical patient file, Phone call interview
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Diseases, Cardiovascular Risk Factor
Characterization of Cardiovascular Diseases and Risk Factors in Patients With Suspected SARS-CoV2/Covid-19 Infection
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects host-cells via ACE2-receptors, which leads to pneumonia (COVID-19) but also can lead to myocarditis (acute myocardial injury) and chronic damage to the…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, SARS
- Trial name
- NCT04327479
- Testing
- Assessment of cardiovascular diseases and cardiovascular risk factors
- Where
- Germany
- Volunteers
- 728 people
- Sponsor
- University Hospital, Essen
COVID-19
Effect of Virtual Reality in Patients With Long Covid-19
SARS-CoV-2 was first detected in Wuhan, Hubei Province, China, in late 2019. It is a highly contagious virus that has been reported to occur in humans and is said to cause pneumonia.
- Trial name
- NCT06374446
- Testing
- Classical Treatment, Virtual Reality Combined with Classical Treatment, Virtual Reality
- Volunteers
- 56 people
- Sponsor
- Istinye University
COVID-19 Patients
Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
COVID-19 caused an unprecedented international crisis. There is an urgent need for an effective regimen to cure this illness. Anecdotal data and some prospective results suggested a role of antimalarial drugs (chloroquine and…
- Trial name
- COVID19-HOPE (NCT04374903)
- Testing
- HCQ & AZ vs HCQ+SIR
- Where
- Jordan
- Sponsor
- King Hussein Cancer Center
Covid19, AKI
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection
The coronavirus (COVID-19) pandemic has created a significant strain on health care resources across the world for managing critically ill patients.
- Conditions
- Covid19, AKI, CKD, ESRD
- Trial name
- NCT04491227
- Where
- 12 sites in United States, Bolivia and 4 more
- Volunteers
- 2,000 people
- Sponsor
- University of California, San Diego
Coronavirus, Covid19
Inflammatory Signal Inhibitors for COVID-19 (MATIS)
The Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19 (MATIS) study is a two-stage, open-label, randomised controlled trial assessing the efficacy of ruxolitinib (RUX) and fostamatinib (FOS) individually, compared to…
- Conditions
- Coronavirus, Covid19, Pneumonia
- Trial name
- MATIS (NCT04581954)
- Testing
- Ruxolitinib, Fostamatinib, Standard of care
- Where
- 5 sites in United Kingdom
- Volunteers
- 185 people
- Sponsor
- Imperial College London
Corona Virus Infection, SARS-CoV 2
Registry for Clinical Presentation and Management of Patients With COVID-19 in the Emergency Room
Patients with COVID-19 usually present in the ED and receive their initial medical check-up here. We will try to gather information of comorbidities and other conditions at the time of presentation of COVID-19 patients to the ED.
- Trial name
- ReCovER (NCT04351854)
- Testing
- Retrospective data collection
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Cologne
Multiple Sclerosis, Healthy
COVID-19 Vaccine Response in Treated MS Patients
The primary goal of this study is to assess the impact of the two major disease modifying therapy (DMT) classes (B cell therapies and S1P modulators) on humoral and cell-mediated immunity to SARS- CoV-2 vaccination compared to…
- Trial name
- NCT05060354
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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