Clinical trials: SARS-COV2 Infection
Sars-CoV2
Study of Kinetics and Efficacy of the Immune Response Against COVID-19 Among Hospital Staff
COVID-19 is a pathology linked to the SARS-CoV-2 virus, a new virus of the coronaviridae family that emerged in China in December 2019 before rapidly becoming a pandemic according to the WHO on March 11, 2020.
- Trial name
- IMMUNO-COVID (NCT04408001)
- Testing
- Clinical interview, Blood collection, Saliva collection
- Where
- France
- Volunteers
- 499 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
COVID-19, Inflammatory Response
Severe COVID-19 Infection in Children Presenting to EDs in Israel and England
Even though the COVID-19 pandemic is no longer at its peak, the threat still lingers. Engaging in prospective surveillance studies will enable us to monitor the disease and prepare for any potential resurgence.
- Trial name
- SPICE (NCT06434701)
- Testing
- Nasopharyngeal swab sampling for COVID-19
- Where
- 6 sites in Israel
- Volunteers
- 500 people
- Sponsor
- Hadassah Medical Organization
Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2
Evaluation of Sedation in COVID-19 ARDS
This study focuses on the evaluation of various factors repeatedly discussed in relation to the impaired sedation of intubated ventilated COVID-19 patients.
- Conditions
- Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2, Hypnotics and Sedatives, Pulmonary Ventilation
- Trial name
- NCT04667936
- Testing
- Treatment group
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Goethe University
Susceptibility to Viral and Mycobacterial Infection
Efficacy of a Self-test and Self-alert Mobile Applet in Detecting Susceptible Infection of COVID-19
The "COVID-19 infection self-test and alert system" (hereinafter referred to as "COVID-19 self-test applet") jointly developed by Beijing Tsinghua Changgung Hospital, Institute for precision medicine, artificial intelligence of…
- Trial name
- COVID-19 (NCT04256395)
- Testing
- mobile internet survey on self-test
- Where
- China
- Volunteers
- 102,456 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
COVID-19
Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19
Clinical, control, double-blind, randomized experimentation with N-acetylcysteine and bromhexine for COVID-19.
- Trial name
- NCT04928495
- Testing
- Vitamin C, N-acetylcysteine (NAC), NAC + Bromhexine (BMX)
- Where
- Brazil
- Volunteers
- 219 people
- Sponsor
- Universidade Federal do Ceara
COVID-19
Investigation of the Muscle Oxygenation in Patients With Post COVID-19 Syndrome
More than 60% of patients infected with COVID-19 have long-term symptoms. These symptoms are associated with common ground-glass opacities on computed tomography scans and chest radiographs.
- Trial name
- NCT05957575
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University
Covid19
Nasopharynx Microbiota Component and in Vitro Cytokines Production in Coronavirus Disease (COVID-19)
The investigators will study nasopharunx microbiota composition, RNA sequences and in vitro cytokines production by peripheral blood cells of COVID-19 patients (both mild-moderate and severe cases) (comparing with convalescent…
- Trial name
- 8796 (NCT04708912)
- Testing
- Observation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cardiac Surgery, COVID
Patient Recovery From Heart Surgery During the Covid-19 Pandemic
This study will describe and explore the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will include mortality, morbidity, health-related quality of life, event-specific distress and…
- Trial name
- CardiacCovid (NCT04366167)
- Testing
- Cardiac surgery
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- Barts & The London NHS Trust
COVID-19, Virus Diseases
Bacillus Calmette-guérin Vaccination to Prevent COVID-19
Based on findings of the interim analysis of the ACTIVATE study showing 53% decrease of the incidence of all new infections with BCG vaccination, a new trial is designed aiming to validate if BCG can protect against COVID-19…
- Conditions
- COVID-19, Virus Diseases, Corona Virus Infection, Coronary Heart Disease
- Trial name
- ACTIVATEII (NCT04414267)
- Testing
- BCG vaccine
- Where
- 15 sites in Greece
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
Covid19
Cardiac and Lung Assessment of Professional Soccer Players Following COVID-19 Disease
During this world COVID-19 outbreak, and according to the experience of team doctors, after their return, some players could have been affected by the SARS-cov2.
- Trial name
- NCT04871867
- Where
- France
- Volunteers
- 60 people
- Sponsor
- American Hospital of Paris
Covid19
Decision Support System Algorithm for COVID-19 Diagnosis
COVID-19 is an infectious disease caused by a newly discovered Coronavirus which was first identified in Wuhan, China in December 2019.
- Trial name
- NCT04479319
- Testing
- Thorax CT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 3,215 people
- Sponsor
- Ankara University
Virus Diseases, Epidemiology
Post-COVID-19 Monitoring in Routine Health Insurance Data
The SARS-CoV-2 infection was in 2020 responsible for new disease related chronic conditions which have been referred to as Post-COVID. To date it is still unknown how common this condition is and which symptoms are related to it.
- Trial name
- POINTED (NCT05074953)
- Testing
- Exposed to a SARS-CoV-2 infection
- Where
- Germany
- Volunteers
- 157,134 people
- Sponsor
- Technische Universität Dresden
COVID-19
Scripps-eMed Covid-19 Study: A Prospective Monitoring Study for Those Individuals Treated With Paxlovid
A prospective monitoring study for those individuals treated with Paxlovid
- Trial name
- NCT05618600
- Where
- United States
- Volunteers
- 917 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Dementia, Mild Cognitive Impairment
Virtual Chair Yoga for Older Adults and Caregivers: Randomized Controlled Trial
Over 700,000 Canadians are affected by dementia costing the health care system approximately $10 billion/year. Due to COVID-19, the government has urged individuals over the age of 70 to stay home, putting this population at risk…
- Trial name
- NCT04884529
- Testing
- Chair-yoga program
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
COVID-19
CORonavirus (COVID-19) Diagnostic Lung UltraSound Study
This observational study is designed to assess whether focused lung ultrasound examination can improve the diagnosis of COVID-19 lung disease and/or make an alternative diagnosis at a patient's initial hospital presentation.
- Trial name
- COR-DLUS (NCT04351802)
- Testing
- Lung ultrasound
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University Hospital Plymouth NHS Trust
Hematologic Neoplasms, COVID-19 Vaccines
Analysis of Immunogenicity, Safety and Efficacy of COVID-19 Vaccines in Immunosuppressed Individuals
The study will evaluate the immunogenicity, safety and efficacy of vaccines against severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) in oncohematological patient population and compare the results with patients…
- Trial name
- NCT04871165
- Testing
- S-binding IgG, RBD-binding IgG and N-binding IgG immunoassays and SARS-CoV-2 serum neutralization assay, quantitative serum immunoglobulin tests, Assessment of proinflammatory cytokine production and immunophenotypic analysis after stimulation with overlapping S-peptides in peripheral blood mononuclear cells (PBMC), Quantitative sequencing for TCR repertoires for SARS-CoV-2-specific antigens
- Where
- Lithuania
- Volunteers
- 3,270 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Covid19, Respiratory Function Loss
Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients
COVID-19 infection is the cause of the current pandemic, responsible for loss of life and disability at a rate unseen before. Among survivors, the infection may cause lasting damage, such as permanent loss of lung function.
- Conditions
- Covid19, Respiratory Function Loss, Coronavirus Infection, Pneumonia, Viral
- Trial name
- NCT04826731
- Testing
- Incentive Spirometer/Respiratory Exerciser
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
COVID-19 Experience
Data Collection on the Model Schools Pediatric Health Initiative at 5 SBHC Sites: COVID-19 Questionnaire
The Model School Pediatric Health Initiative arose out of concern about health access inequities and disparities among some of Toronto's most vulnerable children living in our inner-city neighborhoods.
- Trial name
- SBHC (NCT04534595)
- Testing
- COVID-19
- Where
- Canada
- Volunteers
- 851 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Delivery; Trauma, Covid19
Delivery During Covid-19 Pandemic: Implications for Obstetrics, Maternal Psychopathology, and Mother-Infant Relationship
The Coronavirus 2019 (COVID-19) pandemic has brought about unprecedented social, economic and mental-health challenges, especially for vulnerable populations such as pregnant and post-partum females.
- Trial name
- NCT04609501
- Where
- Israel
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Type 1 Diabetes
COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management
Lockdown resulting from the COVID-19 pandemic was an unpreceded model of the impact of lifestyle on chronic diseases, especially for adolescents and young adults with type 1 diabetes (T1D) whose lifestyle is known to strongly…
- Trial name
- COVIDIABADO (NCT04669912)
- Testing
- glucose control and sensor usage
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Sud Francilien
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