Clinical trials: SARS-COV2 Infection
Hematopoietic and Lymphatic System Neoplasm
Self-Amplifying mRNA COVID-19 Vaccine (LUNAR-COV19) Versus Comirnaty Vaccine in Adult Hematopoietic Cell Transplant Patients
This phase IIb trial compares the effect of LUNAR-COV19 vaccine to Comirnaty vaccine in treating adult patients who have received a hematopoietic cell transplant (HCT).
- Trial name
- NCT07390968
- Testing
- SARS-CoV-2 mRNA Vaccine ARCT-021, Tozinameran, Biospecimen Collection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Fred Hutchinson Cancer Center
Covid19
Impact of the COVID-19 Pandemic on Vaccination
The vaccination policy is drawn up in France by the French Minister of Health, who makes public the vaccination schedule after the opinion of the High Authority of Health.
- Trial name
- COVIDVacImpac (NCT04657263)
- Testing
- Vaccine coverage assessment
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Tension-Type Headache, Orofacial Pain
Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients
Considering the auxiliary potential effect of photobiomodulation in controlling persistent CTT and TMD-related pain in patients who have been diagnosed with COVID-19, and are recovered from the viral infection, we intend to…
- Conditions
- Tension-Type Headache, Orofacial Pain, COVID-19
- Trial name
- NCT05430776
- Testing
- Photobimodulation
- Where
- 2 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
COVID-19 (Healthy Volunteers)
Safety, Reactogenicity, and Immunogenicity Study of Heterologous Booster Vaccination of a SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine (GBP510)
This is randomized, placebo-controlled, observer-blinded, multi-center study to assess safety, reactogenicity and immunogenicity of booster vaccination of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted…
- Trial name
- NCT05175950
- Testing
- SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine (GBP510) (RBD of SARS-CoV-2 25ug / dose) Adjuvanted with AS03, Normal saline
- Where
- 9 sites in South Korea
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
COVID-19 Pneumonia
Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19
This randomized controled open label clinical trial conducted in patients with hypoxemic respiratory failure admitted to the ICU and requiring ventilatory support (invasive or non-invasive) is to evaluate whether treatment with…
- Trial name
- NCT04979221
- Testing
- Cyproheptadine
- Where
- Brazil
- Volunteers
- 274 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
COVID-19
CareSuperb COVID-19 Antigen Test Usability
The purpose of this study is to evaluate the usability of the CareSuperb COVID-19 Antigen Home Test in Home Use.
- Trial name
- NCT05629455
- Testing
- CareSuperb COVID-19 Antigen Home Test Kit
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AccessBio, Inc.
Covid19
Prophylaxis for COVID-19: Ivermectin in Close Contacts of COVID-19 Cases (IVERNEX-TUC)
Randomized controlled clinical trial on using oral ivermectin in COVID-19 prophylaxis supplying the drug to close contacts of confirmed cases.
- Trial name
- IVERNEX-TUC (NCT04894721)
- Testing
- Ivermectin
- Where
- Argentina
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ministry of Public Health, Argentina
Chronic Pain, Morbidity, Multiple
Registry of Coronavirus Complications - CORRELATION WITH GLYCOMIC PROFILE in COVID-19 Patients
COVID infection has resulted in multi-organ injury and may result in cardiovascular, pulmonary, neurological, and muscular damage.
- Conditions
- Chronic Pain, Morbidity, Multiple, Covid19
- Trial name
- ROCCO (NCT04788433)
- Testing
- glycomic analysis, Phone interview
- Where
- Italy
- Volunteers
- 374 people
- Sponsor
- Papa Giovanni XXIII Hospital
Endoscopy, Communication
Impact of Digital Communication Assist Tools in Endoscopic Team Communication During COVID-19
Team work is highly challenged by the COVID-19 pandemic. Necessary protective equipment as FFP-mask and face shields impair communication significantly.Objective of the study is to evalaute the impact of digital enhanced…
- Trial name
- EndoCom (NCT04680858)
- Testing
- DECT
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Ulm
Depression, COVID 19
Descriptive Study of the PSYchological Impact of CONFinement Measures in the General Population
Quarantine is an unpleasant experience : separation from loved ones, loss of freedom, uncertainty about infection status, boredom.
- Trial name
- PsyConfPop (NCT04374643)
- Testing
- Slef questionnaires fulfilment
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
COVID-19
Colchicine to Reduce Cardiac Injury in COVID-19 (COLHEART-19)
Participants will be randomized in a 1:1 ratio to receive Colchicine plus current care per UCLA treating physicians versus current care per UCLA treating physicians alone (control arm).
- Trial name
- COLHEART-19 (NCT04355143)
- Testing
- Colchicine Tablets, Current care per UCLA treating physicians
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- University of California, Los Angeles
Influenza
Detection of Influenza or SARS-CoV-2 Infection by IMS of Nasal Air Sampling
Multicapillary Ion mobility spectrometry of nasal air aspirates shall be investigated as screening tool for the detection of Influenza and SARS-CoV-2- infection.
- Trial name
- NCT04282135
- Testing
- MCC IMS
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Klinikum Bayreuth GmbH
Covid19, Myeloma Multiple
Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden
This retrospective observational cohort study aims to describe the impact of COVID-19 in patients treated with autologous stem cell transplantation (ASCT) for malignant disease in terms of risk factors, morbidity, need for…
- Conditions
- Covid19, Myeloma Multiple, Malignant Lymphoma, Hematologic Neoplasms
- Trial name
- AutoCOVID-19 (NCT04760184)
- Testing
- Autologous stem cell transplantation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Long COVID
A Practical RCT of TCM in the Treatment of LCOVID and Analysis of Syndrome Types and Medication Characteristics.
This is a multi-center, outcome assessor-blinded, practical randomized controlled trial, aiming to compare the actual clinical effectiveness of individualized traditional Chinese medicine and conventional Western medicine in the…
- Trial name
- NCT06095258
- Testing
- Traditional Chinese medicine treatment, Western medicine treatment
- Volunteers
- 162 people
- Sponsor
- Chinese University of Hong Kong
COVID-19
Study to Assess the Efficacy and Safety of STI-1558 in Adult Subjects With Mild or Moderate (COVID-19)
This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study to evaluate the efficacy and safety of STI-1558 in adult subjects with mild/moderate COVID-19.
- Trial name
- NCT05716425
- Testing
- STI-1558
- Where
- 2 sites in China
- Volunteers
- 1,218 people
- Sponsor
- Zhejiang ACEA Pharmaceutical Co. Ltd.
Long COVID Syndrome
A Fasting Pilot Study for Long COVID
Background Long COVID (LC) is a chronic multisystemic condition which substantially impact the quality of life. Despite the staggering burden of LC, there is still no effective treatment.
- Trial name
- NCT07418567
- Testing
- prolonged fasting
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Université de Sherbrooke
Pregnancy Related, Mothers
COVID-19 Vaccine Confidence Among Pregnant Women and Mothers
The purpose of this study is to assess the level of vaccine confidence and influencers among pregnant women and mothers of school-aged children during the COVID-19 pandemic.
- Trial name
- VCCOVID (NCT04694664)
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Pregistry
COVID-19
Angiotensin 1-7 as a Therapy in the Treatment of COVID-19
Phase 2 ,double blind, randomized study of therapy with Angiotensin 1-7 in COVID-19 patients. 120 confirmed SARS-CoV-2 infected patients who exhibit moderate- clinical symptoms including dyspnea, cough and fever, hospitalized in…
- Trial name
- NCT04605887
- Testing
- Angiotensin 1-7
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Rambam Health Care Campus
COVID-19 Testing, CNS Disease
Determination of COVID-19 Related Virus in Central Nervous System
Coronavirus disease 2019 (COVID-19) is a highly infectious pandemic disease caused by SARS-CoV-2 virus. Central Nervous System (CNS) complications associated with COVID-19 might be secondary sequelae due to exuberant systemic…
- Conditions
- COVID-19 Testing, CNS Disease, CNS Infection
- Trial name
- NCT04775784
- Testing
- Determination of SARS-CoV2 presence in CNS
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele
Psychiatric Disorder, Aging
Stress, Personality, Attachment and Coping During the Covid Crisis.
Because of containment due to Covid-19, the French High Authority for Health (HAS) recommended reinforced monitoring of patients taken in care in the psychiatric ward, with special attention for people over the age of 65.
- Trial name
- STERACOVID (NCT04760795)
- Testing
- PTSD Check List (PCL) scale, Brief COPE scale, GAD-7 (Generalized Anxiety Disorder) scale (during containment)
- Where
- 2 sites in France
- Volunteers
- 117 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
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