Clinical trials: SARS-COV2 Infection
Inflammatory Bowel Diseases, Rheumatic Disorder
Impact of Adalimumab Withdrawal or Continuation on Severity of COVID-19 and Risk of IMID Relapse
This study is a retrospective pharmacological study, of a historical cohort. Collection of Retrospective data from February 2020 to 30 September 2021 The index date is the date of COVID-19 positive PCR test.
- Trial name
- COV-ADA (NCT05706038)
- Testing
- Adalimumab
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- IRCCS San Raffaele
COVID-19
Clinical Study To Evaluate The Performance And Safety Of Favipiravir in COVID-19
This study evaluates treatment with Favipiravir combined with supportive care for adult patients with COVID-19-moderate type.
- Trial name
- NCT04336904
- Testing
- Favipiravir
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Giuliano Rizzardini
Herbal Interaction
To Evaluate the Efficacy and Safety of "Rongyang Zhengyifang" Tea Bag With COVID-19 Variant Virus
The strategy of our study is to use traditional Chinese medicine tea to regulate physical fitness and strength can be enhanced to help patients with mildly diagnosed COVID-19 variant virus to achieve self-recovery ability and…
- Trial name
- NCT05504447
- Testing
- Rong-Yang Zhengyifang" tea bag
- Where
- Taiwan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Inflammatory Bowel Diseases
Survey Study About Endoscopy During COVID-19 Pandemic for IBD Doctors
Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of patients and health care…
- Trial name
- NCT04970849
- Testing
- observation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Menstrual Irregularity, Covid 19
Menstrual Cycle Characteristics of Healthcare Professionals
The Covid-19 pandemic has impacted healthcare workers physically and psychologically. The aim of this study is to examine whether there is a change in menstrual cycle characteristics during pandemia.
- Trial name
- NCT04413058
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Haydarpasa Numune Training and Research Hospital
COVID 19
Neuropathology in Adults Intensive Care Unit Patients With COVID 19
This is a single center observational autopsy study, conducted during the first wave of the coronavirus disease (COVID-19) pandemic in France.
- Trial name
- NCT04453670
- Testing
- autopsy
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University of Versailles
Pneumonia, Viral, COVID-19 Pneumonia
Evaluation of Postmortem Pulmonary Interstitial Fibrosis Severity and EGFR Positivity in Covid-19 Pneumonia
The aim of this study is to examine the relationship between the severity of fibrosis in the lung tissue and EGFR positivity in patients who died due to covid-19 pneumonia, with the demographic characteristics, comorbidities…
- Conditions
- Pneumonia, Viral, COVID-19 Pneumonia, EGFR Amplification
- Trial name
- NCT05290441
- Testing
- None involvement
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Kidney Transplant Infection, SARS-CoV Infection
Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19)
None of the vaccines approved, or in clinical trials, have so far been tested on transplanted patients. If they produce an immune response to the Spike protein of SARS-CoV-2 it is unknown how long the protective immunity will…
- Trial name
- SCV-KTx-imm (NCT04747522)
- Testing
- SARS-CoV-2 vaccine
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Primary Myelofibrosis (PMF), Post Polycythemia Myelofibrosis (PPV MF)
Managed Access Programs for INC424, Ruxolitinib
The purpose of this registration is to list Managed Access Programs (MAPs) related to INC424, Ruxolitinib
- Conditions
- Primary Myelofibrosis (PMF), Post Polycythemia Myelofibrosis (PPV MF), Thrombocythemia Myelofibrosis (PET-MF), Severe/Very Severe COVID-19 Illness
- Trial name
- NCT04745637
- Testing
- Ruxolitinib
- Sponsor
- Novartis Pharmaceuticals
Ozone Therapy for Covid 19 Pneumonia Patients
Evaluation of Post-covid 19 Patients Who Receive Ozonetheraphy With Thorax CT
It is known that enhances wound healing by oxidative stress and supports immune system besides it is cheap and has not any side effects.
- Trial name
- NCT04789395
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
COVID-19
PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US
IMPAACT 2032 was a Phase IV prospective, open label, non-randomized opportunistic study. The objectives of this study were to describe the pharmacokinetic (PK) properties and safety of remdesivir (RDV) administered intravenously…
- Trial name
- NCT04582266
- Testing
- Remdesivir
- Where
- 10 sites in United States
- Volunteers
- 54 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Participant
Drug-Drug Interaction Study Assessing Effect of Itraconazole on PF-07321332/Ritonavir in Healthy Participants
The purpose of this study is to estimate the effect of a strong inhibitor of CYP3A4 (itraconazole) on the pharmacokinetics (PK) of PF-07321332/ritonavir in healthy participants.
- Trial name
- NCT04962022
- Testing
- PF-07321332/ritonavir, Itraconazole
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.
- Conditions
- COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle, Remodeling, Vascular, Left Ventricular Dysfunction
- Trial name
- MYOFLAME-19 (NCT05619653)
- Testing
- Prednisolone, Losartan
- Where
- 5 sites in Austria, Germany
- Volunteers
- 279 people
- Sponsor
- Valentina Puentmann
SARS-CoV-2, COVID-19
eVusheld Assessment reaL wORld Effectiveness in the VA Health System
An AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and…
- Trial name
- VALOR-VA (NCT05663957)
- Testing
- Evusheld
- Where
- United States
- Volunteers
- 5,814 people
- Sponsor
- AstraZeneca
COVID-19
Lung Injury (Pulmonary Edema) in COVID-19: Treatment With Furosemide and Negative Fluid Balance (NEGBAL)
In COVID-19, pulmonary edema has been attributed to "cytokine storm". However, it is known that SARS-CoV-2 promotes angiotensin-converting enzyme 2 deficiency, it increases angiotensin II and this triggers volume overload.
- Trial name
- NCT05304702
- Where
- Argentina
- Volunteers
- 120 people
- Sponsor
- Clinica Colon
COVID-19, SARS-COV-2 Infection
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age
This study is designed to find out how well the COVID-19 vaccine protects people 50 to 64, who don't have any serious health problems, compared to a group that receives a vaccine that doesn't contain an ingredient to protect…
- Trial name
- NCT07300839
- Testing
- BNT162b2 Vaccine
- Where
- 196 sites in United States
- Volunteers
- 5,240 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Covid19
COVID SAFE: COVID-19 Screening Assessment for Exposure
In order to safely and effectively reopen businesses and universities across the US, institutions will need to develop approaches to rapidly identify COVID-19 cases and manage their spread while balancing program effectiveness…
- Trial name
- COVID SAFE (NCT04508777)
- Testing
- Saliva-based testing
- Where
- United States
- Volunteers
- 1,759 people
- Sponsor
- University of Pennsylvania
Post COVID-19 Condition
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).
- Trial name
- NCT06865222
- Testing
- Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 2 weeks, Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 4 weeks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
COVID-19
Study of Remdesivir in Participants Below 18 Years Old With COVID-19
The goals of this clinical study are to learn more about the study drug, remdesivir, and how safe it is in participants less than 18 years old with coronavirus disease 2019 (COVID-19).
- Trial name
- CARAVAN (NCT04431453)
- Testing
- Remdesivir
- Where
- 32 sites in United States, Italy and 2 more
- Volunteers
- 59 people
- Sponsor
- Gilead Sciences
COVID-19 Infection
Changes in Seroprevalence and Wellness Over Time in Healthcare Workers (CONSERVE-HCW)
The Investigators propose a multi-center, observational, longitudinal, cohort study of the serology and wellness of HCWs over a year of the COVID-19 pandemic.
- Trial name
- CONSERVE-HCW (NCT04595175)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Brian Tiffany, MD
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