Clinical trials: SARS-COV2 Infection
COVID-19
INB03 for the Treatment of Pulmonary Complications From COVID-19
The purpose of this study is to determine whether XPro1595 can prevent the progression of respiratory complications in COVID19 patients.
- Trial name
- NCT04370236
- Testing
- INB03
- Where
- 9 sites in United States
- Volunteers
- 79 people
- Sponsor
- Inmune Bio, Inc.
COVID19
Phase I/II Safety, Dose Finding & Antiviral Activity of RD-X19 in Mild/Moderate Outpatient COVID-19
This randomized, Phase I/II feasibility study will evaluate the safety and efficacy of the RD-X19 device in SARS-CoV-2 infected individuals with uncomplicated COVID-19.
- Trial name
- NCT04662671
- Testing
- RD-X19
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- EmitBio Inc.
Coronavirus Infection, Coronavirus
Convalescent Plasma for Patients With COVID-19
Pilot study of tolerability and efficacy of transfusion of 200mL of convalescent plasma in patients with COVID-19 respiratory disease.
- Conditions
- Coronavirus Infection, Coronavirus, COVID
- Trial name
- NCT04385199
- Testing
- Convalescent plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Henry Ford Health System
SARS-CoV-2
Post-Marketing Safety Study in Japan of Shock and Anaphylaxis After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine in Persons in at High Risk of Severe COVID-19
The goal of this study is to confirm the onset status of hypersensitivity reactions including shock and anaphylaxis observed after vaccination with this drug in persons with underlying diseases who are considered to have a high…
- Trial name
- NCT05894499
- Where
- Japan
- Volunteers
- 13,309 people
- Sponsor
- ModernaTX, Inc.
Patients Undergoing Elective Surgery With Anesthesia
Telemedical Risk Assessment and Preoperative Evaluation (TAPE)
The purpose of this study is to assess the feasibility, patient satisfaction and time saving of a telemedical risk assessment and preoperative evaluation for anesthesia.
- Trial name
- NCT04518514
- Testing
- TAPE-Software
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Long COVID
A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID
The IMPACT Long Covid Treatment clinical study (IMPACT-LC) is testing two repurposed and previously approved drugs, Maraviroc and Atorvastatin, for the treatment of non-hospitalized subjects with Long COVID.
- Trial name
- IMPACT-LC (NCT06974084)
- Testing
- Maraviroc (MVC), Atorvastatin, 10mg, 20mg, 40mg
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- HealthBio, Inc.
Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease
Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)
This phase III trial compares the effect of adding tocilizumab to standard of care versus standard of care alone in treating cytokine release syndrome (CRS) in patients with SARS-CoV-2 infection.
- Conditions
- Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease, Chronic Renal Failure, Coronary Artery Disease
- Trial name
- NCT04361552
- Testing
- Best Practice, Tocilizumab
- Where
- United States
- Sponsor
- Emory University
COVID-19, Coronavirus Infection
Efficacay of Chloroquine or Hydroxychloroquine in COVID-19 Treatment
Chloroquine or hydroxychloroquine in COVID-19 treatment
- Trial name
- NCT04353336
- Testing
- Chloroquine or Hydroxychloroquine
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Tanta University
COVID-19, COVID-19 Pandemic
Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis
The purpose of this retrospective study is to evaluate the effectiveness of CPM nasal spray as part of the treatment of COVID-19 and its impact on clinical symptoms. Two cohort groups will be compared (CPM vs. standard care).
- Conditions
- COVID-19, COVID-19 Pandemic, COVID-19 Respiratory Infection, SARS CoV 2 Infection
- Trial name
- ACCROS-R (NCT05520944)
- Testing
- ClorNovir® (Chlorpheniramine) 0.4% Nasal Spray
- Where
- Dominican Republic
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr. Ferrer BioPharma
Venous Thromboembolism, Covid19
COVID-19 and Venous Thromboembolism Risk
Coronavirus disease 2019 (Covid-19) is now a leading cause of death among U.S. adults. In addition to profound respiratory and multi-organ failure, hypercoagulable states and venous thromboembolism (VTE) have been increasingly…
- Trial name
- NCT04569344
- Testing
- Laboratory test positive for SARS-CoV-2 virus
- Where
- 2 sites in United States
- Volunteers
- 398,530 people
- Sponsor
- University of California, San Francisco
Anxiety State, Depression
Stress Levels and Mental Well-Being Among Slovak Students During e-Learning
Introducing restrictions on human contact has been effective in preventing the uncontrolled spread of COVID-19, however, it appears to have negatively impacted mental health.
- Trial name
- NCT04924634
- Testing
- Stress Levels and Mental Well-Being assessment
- Where
- Poland
- Volunteers
- 3,051 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Coronavirus Infection
C-reactive Protein Levels Among Individuals With COVID-19
The primary objective of this multi-center study is to clarify the value of a CRP measurement for triage of patients initially presenting with light symptoms of the COVID-19 infection.
- Trial name
- NCT04373798
- Testing
- C-reactive protein
- Where
- Denmark
- Volunteers
- 1,006 people
- Sponsor
- Henning Bliddal
ARDS, Hypercapnic Respiratory Failure
Low-flow Extracorporeal Carbon Dioxide Removal in COVID-19-associated Acute Respiratory Distress Syndrome
The study aims to investigate the efficacy of extracorporeal CO2 removal for correction of hypercapnia in coronavirus disease 19 (COVID-19)-associated acute respiratory distress syndrome
- Conditions
- ARDS, Hypercapnic Respiratory Failure, AKI
- Trial name
- NCT04351906
- Testing
- ECCO2R
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Giessen
SARS-CoV-2
Post-marketing Surveillance (PMS) Use-Result Surveillance With SPIKEVAX BIVALENT, SPIKEVAX X Injection, SPIKEVAX JN Injection and SPIKEVAX IN PRE-FILLED SYRINGE
The main objective of the surveillance is to evaluate the incidence of the adverse events (AEs), and other safety-related information in South-Korean population.
- Trial name
- NCT06333704
- Testing
- SPIKEVAX Bivalent BA.1, SPIKEVAX Bivalent BA.4/5, SPIKEVAX XBB.1.5
- Where
- 26 sites in South Korea
- Volunteers
- 4,207 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Corona Virus Infection
CORIMUNO-ANA: Trial Evaluating Efficacy Of Anakinra In Patients With Covid-19 Infection
The overall objective of the study is to determine the therapeutic effect and tolerance of Anakinra in patients with moderate, severe pneumonia or critical pneumonia associated with Coronavirus disease 2019 (COVID-19).
- Trial name
- CORIMUNO-ANA (NCT04341584)
- Testing
- Anakinra
- Where
- France
- Volunteers
- 161 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID
Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19
we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19.
- Trial name
- NCT04447534
- Testing
- Chloroquine or hydroxychloroquine, zinc
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Tanta University
Stigma, Social, Help-Seeking Behavior
Digital Mental Health Care for COVID-19 High-Risk Populations - Phase 2
The mental health consequences of the COVID-19 (Coronavirus Disease of 2019) pandemic are likely to be vast, exceeding the capacity of mental health services and delaying treatment for people in need, with devastating…
- Trial name
- NCT05826132
- Testing
- Adjusted Content Intervention, Non-Adjusted Intervention Video
- Where
- United States
- Volunteers
- 1,402 people, healthy volunteers welcome
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
COVID-19 Respiratory Infection
An Observational, Ambispective Cohort Study of Azvudine in the Treatment of Patients With COVID-19 Pneumonia
This is a multicenter, ambispective observational cohort study. The patients with corona virus disease 2019 (COVID-19) will be included in the study.
- Trial name
- NCT05621993
- Testing
- Azvudine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Qianfoshan Hospital
COVID-19
Povidone-Iodine Oral Rinse Study
This study is a two-arm, randomized, 2-phase study. Phase I will be double blinded clinical trial of the safety and efficacy of an antiseptic mouthwash solution on reducing SARS-CoV-2 load in COVID 19+ adult individuals.
- Trial name
- NCT05239598
- Testing
- Mouth rinse
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
SARS-CoV-2, Hypoxia
Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment
Abstract Background: Clinicians in pulmonary critical care medicine and critical care medicine considered dapsone administration to treat SARS-CoV-2 inflammasome.
- Conditions
- SARS-CoV-2, Hypoxia, ARDS
- Trial name
- NCT04918914
- Testing
- Dapsone 100 MG
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hunt Regional Medical Center
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