Clinical trials: SARS-COV2 Infection
COVID, Neurologic Manifestations
Neurologic Manifestations of COVID 19 in Children
The purpose of this study is to perform a secondary analysis of pre-existing de-identified limited datasets obtained from sites participating in Tier 1 (STUDY20040154: Neurologic Manifestations of COVID 19 in Children) and Tier 2…
- Trial name
- NCT04379089
- Testing
- Observational study only
- Where
- United States
- Volunteers
- 3,568 people
- Sponsor
- University of Pittsburgh
COVID-19 Severe Respiratory Failure
Combination of Inhaled DNase, Baricitinib and Tocilizumab in Severe COVID-19
In patients with COVID-19, severe hypoxemic respiratory failure (SRF) leading to invasive mechanical ventilation (IMV), raises the mortality rate substantially.
- Trial name
- NCT05279391
- Testing
- Dexamethasone, Low molecular weight heparin, Anakinra 100Mg/0.67Ml Inj Syringe
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Democritus University of Thrace
Diabetes Mellitus, Diabetes Mellitus, Type 2
Glycaemia and Cardiac Function in Patients With COVID-19
The study design is observational, exploratory study consisting of two cohorts of COVID-19 patients admitted to the ICU and the medical ward, respectively.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, COVID
- Trial name
- GLYCOVID-19 (NCT04410718)
- Testing
- Glycaemic levels
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Steno Diabetes Center Copenhagen
Coronavirus Infections, Healthcare Associated Infection
NO Prevention of COVID-19 for Healthcare Providers
Thousands of healthcare workers have been infected with SARS-CoV-2 and contracted COVID-19 despite their best efforts to prevent contamination. No proven vaccine is available to protect healthcare workers against SARS-CoV-2.
- Trial name
- NOpreventCOVID (NCT04312243)
- Testing
- Inhaled nitric oxide gas
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Pain
COVID-19 and Its Effects on Chronic Pain Patients
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Many factors can affect pain and its severity.
- Trial name
- NCT04715815
- Testing
- No intervention (only interview)
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
COVID-19
Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients
The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high…
- Trial name
- NCT04451889
- Testing
- miniprobe Alveoflex
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
Coronavirus, Coronavirus Infection
COVID-19 Infection and Transmission in Exposed, Confined and Community-based Infants
According to epidemiological models, the seroprevalence of SARS-CoV-2 infection in Île-de-France as of 11 May was between 10 and 15%.
- Conditions
- Coronavirus, Coronavirus Infection, Covid19, Sars-CoV2
- Trial name
- COVIDOCRECHE (NCT04413968)
- Testing
- Rapid detection test, Nasopharyngeal swab, Stool collection
- Where
- 11 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19 Respiratory Infection
Musculoskeletal Problems and Endurance in Healthcare Professionals With and Without COVID-19
The effects of frequency and severity of physical complaints and symptoms on general well-being, sleep and quality of life are known.
- Trial name
- NCT05075018
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Covid19
Vaccination With COMIRNATY in Subjects With a VAXZEVRIA First Dose
CombiVacS is a phase 2 randomized, adaptive trial developed to evaluate the immunogenicity of a dose of COMIRNATY after a previous single dose of VAXZEVRIA.
- Trial name
- CombiVacS (NCT05378191)
- Testing
- COMIRNATY
- Where
- 5 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Detection
Post COVID-19 Syndrome Study With Questionnaires and Instruments Measurements
COVID-19 has caused various long-term symptoms affecting different bodily functions. A study shows that traditional Chinese medicine can balance the human body disorder after a virus infection and restore health.
- Trial name
- NCT05862597
- Testing
- HRV and Pulse diagnosis
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Mild to Moderate COVID-19
Phase III Clinical Study Evaluating the Efficacy and Safety of WPV01 in Patients With Mild/Moderate COVID-19
The study is a multicenter, randomized, double-blind, placebo-controlled efficacy, safety Phase III clinical trial designed to evaluate the efficacy and safety of WPV01 in patients with mild/moderate COVID-19.
- Trial name
- NCT06197217
- Testing
- WPV01
- Where
- China
- Volunteers
- 1,350 people
- Sponsor
- Westlake Pharmaceuticals (Hangzhou) Co., Ltd.
COVID-19 Vaccine
SARS-CoV-2 Antibody Response in Children Aged 5-11 Years Following Vaccination Against COVID-19
There are few data on the immunogenicity of the Pfizer-Biontec BNT162b2 vaccine for the prevention of COVID-19 disease and of side effects in children aged 5-11 years.
- Trial name
- NCT05175989
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
SARS-CoV2 Infection, COVID-19
Prevalence and Impact of COVID-19 on Maternal and Infant Health in African Populations
There is growing evidence that COVID-19 threatens maternal and perinatal health. Pregnant women are at higher risk of severe complications (severe pneumonia, hospitalizations, intensive care unit admission, invasive mechanical…
- Trial name
- MA-CoV (NCT05303168)
- Where
- 2 sites in Gabon, Mozambique
- Volunteers
- 1,000 people
- Sponsor
- Barcelona Institute for Global Health
Covid-19, Anosmia
Brain MRI Imaging in Patients With SARS-Cov2 (COVID-19) Infection With or Without Anosmia
To date there is no brain imaging and olfactory data available in COVID-19 positive patients with anosmia. By describing the pathophysiological characteristics underlying the olfactory symptoms and clinical characteristics of…
- Trial name
- ANOSIRM (NCT04408391)
- Testing
- Brain MRI scan
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Critical COVID-19 With Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure
Novel Corona Virus (SARS-CoV-2) is known to cause Respiratory Failure, which is the hallmark of Acute COVID-19, as defined by the new NIH/FDA classification.
- Conditions
- Critical COVID-19 With Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Corona Virus Infection, Acute Lung Injury
- Trial name
- COVID-AIV (NCT04311697)
- Testing
- Aviptadil by intravenous infusion + standard of care, Normal Saline Infusion + standard of care
- Where
- 10 sites in United States
- Volunteers
- 203 people
- Sponsor
- APR Applied Pharma Research s.a.
COVID-19
A Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 Against COVID-19
This is a phase I prospective, open-labeled, single-center study to evaluate the safety and immunogenicity of MVC-COV1901.
- Trial name
- NCT04487210
- Testing
- MVC-COV1901
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medigen Vaccine Biologics Corp.
SARS-CoV2 Infection, COVID-19
COVID-19 MP Biomedicals SARS-CoV-2 Ag OTC: Clinical Evaluation
SARS-CoV-2 rapid antigen over the counter clinical performance evaluation
- Trial name
- NCT05584176
- Testing
- iCura COVID-19 Antigen Rapid Home Test, RT-PCR Test
- Where
- 4 sites in United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- MP Biomedicals, LLC
Depression and Quality of Life Related to the Coronavirus Pandemic
ICBT for Mental Health Problems Related to the Coronavirus Pandemic
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme a on adult mental health problems related to the current coronavirus pandemic.
- Trial name
- NCT04424212
- Testing
- Intervention group CoronaCope
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Linkoeping University
SARS-CoV-2 Acute Respiratory Disease
Study of Ameliorating Effect of COVID-19 mRNA Vaccine in Individuals Immunized With Inactivated Vaccine
this is a voluntary, investigator-initiated, inactivated COVID-19 vaccine controlled clinical trial to evaluate the immunogenicity and safety of COVID-19 mRNA vaccine in adults aged 18 years and above which have immunized with…
- Trial name
- COVID-19 (NCT04944381)
- Testing
- SARS-Cov-2 mRNA vaccine immunization, Inactivated SARS-Cov-2 vaccine immunization
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Qihan Li
COVID19 Pneumonia
N-terminal Pro B-type Natriuretic Peptide and Vitamin D Levels as Prognostic Markers in COVID-19 Pneumonia
This study is designed to assess the difference between level of NT-pro-BNP, and Vitmin D in moderate cases who progressed to severe or critically ill category compared to those who did not.
- Trial name
- NCT04487951
- Testing
- Pro BNP , Vitamin D
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
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