Clinical trials: SARS-COV2 Infection
COVID-19
Thymosin Alpha 1 to Prevent COVID-19 Infection in Renal Dialysis Patients
Thymalfasin (thymosin alpha 1 or Ta1), the active pharmaceutical ingredient in ZADAXIN® injection, is a 28-amino acid synthetic peptide, identical to natural Ta1 produced by the thymus gland.
- Trial name
- Ta1 (NCT04428008)
- Testing
- Thymalfasin
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- William B. Ershler, MD
Colorectal Cancer
It is Possible to Maintain the Performance of Screening Colonoscopies Under MEOPA During the Covid 19 Epidemic Period When Access to the Operating Room is Limited
Feedback: during the COVID-19 epidemic, access to operating theaters was restricted so that anesthetists and nurse anesthetists could reinforce the resuscitation workforce.
- Trial name
- KALINOX19 (NCT05336617)
- Testing
- colonoscopy
- Where
- France
- Volunteers
- 282 people
- Sponsor
- Centre Hospitalier Sud Francilien
COVID-19
Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19
This study will evaluate the efficacy, safety, antiviral activity, and pharmacokinetics of study drug RO7496998 (AT-527) compared to placebo in non-hospitalized adult and adolescent participants with mild to moderate coronavirus…
- Trial name
- MORNINGSKY (NCT04889040)
- Testing
- RO7496998
- Where
- 50 sites in Argentina, Belgium and 10 more
- Volunteers
- 216 people
- Sponsor
- Hoffmann-La Roche
COVID-19, SARS-CoV-2
COVIDISC: Rapid Diagnostic Tests on Nasopharyngeal Swabs for the Detection of COVID-19
The Covid-19 pandemic requires a reliable diagnosis of patients in order to take care of them in the best conditions and in the appropriate services.
- Trial name
- COVIDISC (NCT04703140)
- Testing
- Rapid Diagnostic Test vs PCR
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CMC Ambroise Paré
Post COVID-19 Condition
Improving Health Status in COVID-19 Long-Hauler
This randomized clinical trial investigates the effects of a distance physical activity coaching program on the health of COVID-19 long-hauler.
- Trial name
- NCT06679218
- Testing
- Activity Coaching Programme, Standard medical care and leaflet education
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Granada
Covid19, Critical Illness
Sex Hormone Dysregulations Are Associated With Critical Illness in COVID-19 Patients
Males develop more severe SARS-CoV-2 infection related disease outcome than females. Herein, sex hormones were repeatedly proposed to play an important role in Covid-19 pathophysiology and immunity.
- Trial name
- HAM-SEX-C19 (NCT04979091)
- Testing
- Sex Hormones
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
COVID-19
Study on Sotrovimab and Its Impact on the Immune Response to COVID-19 Infection in Real-life in the UAE and Bahrain
The United Arab Emirates (UAE), the Kingdom of Bahrain, Kuwait, Oman, and Qatar have authorised sotrovimab for emergency use. Local experience among physicians include recent successful COVID-19 vaccine pivotal studies supported…
- Trial name
- NCT05398718
- Testing
- Sotrovimab
- Where
- Bahrain
- Volunteers
- 20,000 people
- Sponsor
- Abu Dhabi Health Services Company
COVID-19, Mental Health Impairment
A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization.
This study presents a digital mental-health protocol designed to offer remote, personalized support to former or current COVID-19 patients. A total of 100 subjects will be enrolled.
- Conditions
- COVID-19, Mental Health Impairment, Telemedicine
- Trial name
- DigiCOVID (NCT05231018)
- Testing
- Psychotherapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Musculoskeletal Pain
Evaluate the Working Environments of Individuals Working From Home During Covid-19 Outbreak
The study aims to evaluate the working environments of individuals working from home during the covid-19 outbreak and the effect of the working environments on their musculoskeletal system.
- Trial name
- NCT04342208
- Where
- Turkey (Türkiye)
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
HIV Infections
COVID-19 Prevalence in HIV-infected Patients
North-east area of France was hit in February 2020 by the new coronavirus disease, more severely than other French regions. Factors affecting the evolution of the disease and its severity have been quickly identified, among them…
- Trial name
- SeCoVIHA (NCT04515225)
- Testing
- Blood Sample
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19 Sequelae
Yale COVID-19 Recovery Study
The general purpose of the study is to determine the change in immune responses in people with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) after vaccination.
- Trial name
- NCT04895189
- Testing
- No intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Covid19
Symptoms and Wellbeing of People Infected With Covid-19 Virus in Iceland
The purpose of this cross-sectional study is to explore symptoms and well being of people diagnosed with COVID-19 from the outset of the pandemic until June 2020.
- Trial name
- NCT04546191
- Where
- Iceland
- Volunteers
- 1,580 people
- Sponsor
- Landspitali University Hospital
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
COVID-19
Passive Immunotherapy In Patients With SARS CoV-2
Plasma from convalescent individuals (convalescent plasma, CP) has been used for more than a hundred years for the treatment of infectious diseases.
- Trial name
- CoV-PlasGal (NCT05578391)
- Testing
- Convalescent plasma
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Post-COVID19 Condition
Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study
PAX is a prospective, randomized (1:1), double-blind, placebo-controlled study, that have as a objective to evaluate the safety and tolerability of plasma exchange (PE) in patients with Post Acute Covid-19 Syndrome (PCC)…
- Trial name
- NCT05445674
- Testing
- Plasma Exchange Procedure
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Health Promotion, Health Education
The Future of Viral Communications: Video-Based Health Promotion Strategies for COVID-19 Vaccinations
The investigators aim to study whether education, in the form of three two-minute educational videos about COVID-19 vaccine development and dissemination, reduces vaccine hesitancy and increases intent to vaccinate.
- Conditions
- Health Promotion, Health Education, COVID-19 Vaccines
- Trial name
- NCT04876885
- Testing
- Educational video
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Covid19
Dual MRI for Cardiopulmonary COVID-19 Long Haulers
The next phase of the COVID-19 pandemic is likely to see a surge in an associated chronic cardiopulmonary disease that will challenge health systems.
- Trial name
- NCT04828135
- Testing
- Hyperpolarized 129Xenon gas
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Bastiaan Driehuys
Post COVID-19 Condition, Long COVID Syndrome
Study to Evaluate the Efficacy and Safety of Plitidepsin in Adults With Post-COVID-19 Condition (PCC)
The study aims to prove that plitidepsin could be an efficacious, safe, and well-tolerated therapy for PCC. To this end, we will perform a randomized, double-blind study comparing the clinical and laboratory benefits of…
- Conditions
- Post COVID-19 Condition, Long COVID Syndrome, Persistent COVID-19, Persistent COVID Condition
- Trial name
- THALASSA (NCT06766825)
- Testing
- Plitidepsin 1.5 mg/day
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Mucormycosis
COVID-19 Associated Mucormycosis: A Multidisciplinary Dilemma in Assiut University Hospital
We aimed to describe the frequency; presentations, predictors, in-hospital outcome of mucormycosis patients in the scope of COVID-19.
- Trial name
- NCT05074043
- Testing
- antiviral, surgical
- Where
- Egypt
- Volunteers
- 433 people
- Sponsor
- Assiut University
Immune Suppression, Immune Deficiency
Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults.
A weekly questionnaire is sent to patients and parents of patients who are vulnerable for infections. Possible symptoms of COVID19 are asked for and use of healthcare services and testing for COVID19.
- Conditions
- Immune Suppression, Immune Deficiency, Infection, COVID
- Trial name
- ImmunoCOVID (NCT04382508)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
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