Clinical trials: SARS-COV2 Virus
Covid19
Changing of Trace Element, Homocysteine, Oxidative Stress Parameters and Physical Activity Levels in Covid-19
With the rapid spread of COVID-19 (SARS-CoV-2) disease all over the world and the announcement of a pandemic, researches on many different drug approaches have begun and these researches continue today.
- Trial name
- NCT04694703
- Testing
- Covid-19 group
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Izmir Bakircay University
COVID-19, SARS-CoV2 Infection
Asymptomatic and Pre-symptomatic Transmission of SARS-CoV-2 in a Community Congregant Setting
The overall aim of this study is to measure how transmission of COVID-19 occurs in communities - including the role of super spreaders and/or identifying conditions that may increase transmission risk, with a focus on congregant…
- Trial name
- NCT05145803
- Testing
- Polyvinylalcohol strip [diagnostic]
- Where
- 6 sites in United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Colorado School of Public Health
Sars-CoV2
Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19
No optimal antiviral intervention has been yet validated to treat COVID-19 disease. Comorbidities, such as older age, obesity, diabetes, history of cardiovascular diseases are associated with poor prognosis.
- Trial name
- HYdILIC (NCT04372082)
- Testing
- Standard of care (SOC), Hydroxychloroquine, Association of diltiazem and niclosamide
- Sponsor
- University Hospital, Lille
SARS CoV 2 Infection, COVID-19
Diagnosis of Respiratory Viruses in Children With Rhinoswab Junior
A study to investigate Rhinoswab as an alternative method to combined throat and deep nasal (CTDN) swab for respiratory sample collection in children who present to the Royal Children's Hospital (RCH) for viral testing.
- Trial name
- NCT05043623
- Testing
- Rhinoswab Junior, Combined nose and throat swab, Saliva swab
- Where
- Australia
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Covid19, Thrombosis
Apixaban for PrOphyLaxis of thromboemboLic Outcomes in COVID-19
Randomized, double-blinded, placebo-controlled trial comparing oral anticoagulation with placebo for community-dwelling patients with symptomatic COVID-19 infection and risk factors for thrombosis.
- Trial name
- APOLLO (NCT04746339)
- Testing
- Apixaban 2.5 MG
- Where
- 4 sites in Brazil
- Volunteers
- 411 people
- Sponsor
- Brazilian Clinical Research Institute
Long Haul COVID, Postural Orthostatic Tachycardia Syndrome
Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
The purpose of the study is three-fold. The primary aim is to identify the proportion of Long-Haul COVID (LHC) and non-LHC volunteers with relevant symptoms actually have postural orthostatic tachycardia syndrome (POTS).
- Trial name
- COVIVA (NCT05481177)
- Testing
- Ivabradine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Uniformed Services University of the Health Sciences
Coronavirus Infection
Efficacy of Probiotics in the Treatment of Hospitalised Patients With Novel Coronavirus Infection
The treatment of the new coronavirus infection (COVID-19) and COVID-19-associated diarrhoea and liver injury remains challenging. Optimizing treatment approaches for COVID-19 remains an issue.
- Trial name
- NCT04854941
- Testing
- Probiotics
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
COVID-19, Venous Thromboembolism
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic
The purpose of this study is to investigate the prevalence of venous thromboembolism in a regional health care system (Region Östergötland, Sweden) before and during the SARS-COV-2 pandemic.
- Conditions
- COVID-19, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04400877
- Testing
- Diagnostic examination for venous thromboembolism
- Where
- Sweden
- Volunteers
- 7,795 people
- Sponsor
- University Hospital, Linkoeping
COVID 19
AiM COVID for Covid 19 Tracking and Prediction
University of Warwick (Coventry, UK) and NTUU "Igor Sikorsky" Kyiv Polytechnic Institute (Kyiv, Ukraine), together with ClickMedix LLC, have developed an app and a chatbot "AiM COVID" for efficient monitoring and mitigation of…
- Trial name
- NCT04354753
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aarogyam UK
Covid-19
Relationship Between Social Status and Use of Healthcare Services During the Confinement Period Linked to the COVID-19 Epidemic
Epidemics have always affected the most disadvantaged social categories more intensely. This social inequality is expressed in the use of care and emergencies: greater frequency but also greater seriousness.
- Trial name
- NCT04703777
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
SARS-CoV-2, COVID-19
VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL)
We propose a 3-arm RCT to determine the efficacy of hydroxychloroquine or azithromycin in treating mild to moderate COVID-19 among Veterans in the outpatient setting.
- Trial name
- VA-REACH (NCT04363203)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Salomeh Keyhani MD
COVID-19, SARS-CoV-2 Infection
Nasal and Pulmonary Nitric Oxide Output in COVID-19 Infection
A Study of the relation of COVID-19 infection and its severity to upper and lower airway nitric oxide, upper airway viral load and lung function.
- Trial name
- NCT04728919
- Where
- Finland
- Volunteers
- 82 people
- Sponsor
- Tampere University Hospital
Severe COVID-19 Disease
RAPA-501-Allo Therapy of COVID-19-ARDS
The first-in-human Phase 1 study component will evaluate two dose levels of RAPA-501-ALLO off the shelf cells in patients with COVID-19-related ARDS, with key endpoints of safety, biologic and potential disease-modifying effects.
- Trial name
- NCT04482699
- Testing
- RAPA-501-Allo off-the-shelf Therapy of COVID-19
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rapa Therapeutics LLC
COVID-19 by SARS-CoV-2 Infection
Frequency and Clinical Evolution of Olfactory and Taste Disorders in COVID-19 Patients
A novel coronavirus SARS-CoV-2 HAS arose in 2019 in Wuhan, China. Beside the classical semiology of this infection, numerous patients described olfactory and teste disorders.
- Trial name
- NCT04361565
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
SARS-CoV-2 Infection, COVID-19
Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva
The investigators hypothesize that detection of SARS-CoV2 on saliva samples will increase the performance of the screening program compared to the reference strategy (RT-PCR on a nasopharyngeal swab).
- Trial name
- SALICOV (NCT04578509)
- Testing
- Nasopharyngeal swab, Saliva sample, axillary sweat sample
- Where
- France
- Volunteers
- 5,197 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma, COPD
MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology
Lung magnetic resonance imaging (MRI) with proton and inhaled inert gases has demonstrated a clinical ability to provide valuable structural and functional information in lung disease.
- Conditions
- Asthma, COPD, Covid19, Long COVID
- Trial name
- MURDOCH (NCT04872309)
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Coronavirus Disease 2019 (COVID-19) Pneumonia
Phase 3 Study to Evaluate Efficacy and Safety of Lenzilumab in Patients With COVID-19
The primary objective of this study is to assess whether the use of lenzilumab in addition to current standard of care can alleviate the immune-mediated cytokine release syndrome (CRS) and improve ventilator-free survival in…
- Trial name
- NCT04351152
- Testing
- Lenzilumab, Standard of Care
- Where
- 29 sites in United States, Brazil
- Volunteers
- 520 people
- Sponsor
- Humanigen, Inc.
COVID-19 Pneumonia
Clinical, Molecular and Functional Biomarkers for PROgnosis, Pathomechanisms and Treatment Strategies of COVID-19
The aim of the joint project PROVID is to contribute to better outcome prediction for COVID-19 patients, to better clinical management, and to the development of new therapies.
- Trial name
- NCT04977934
- Where
- 5 sites in Austria, Germany
- Volunteers
- 94 people
- Sponsor
- Charite University, Berlin, Germany
Covid19, Hemodynamic Instability
Hemodynamic Impact on Critical Care Patients With Lung Damage Secondary to COVID-19
The aim of the present work is to describe the hemodynamic effects shown in patients with ARDS secondary to SARS-CoV-2 infection
- Conditions
- Covid19, Hemodynamic Instability, ARDS, Human
- Trial name
- NCT04556864
- Where
- 5 sites in Spain
- Volunteers
- 67 people
- Sponsor
- Juan Victor Lorente
SARS-CoV-2 Infection, Acute Kidney Injury
Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection
An interventional clinical trial using oral nicotinamide riboside (NR) in hospitalized patients with COVID-19 infection and acute kidney injury to determine the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+)…
- Trial name
- NIRVANA (NCT04818216)
- Testing
- Nicotinamide riboside
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.