Clinical trials: SARS-COV2 Virus
SARS-CoV-2 Acute Respiratory Disease
Clinical Evaluation of the NeuMoDx SARS-CoV-2 Assay (COVID-19)
A multicenter study, using prospectively collected, fresh (Category I) and frozen (Category II), residual/leftover nasopharyngeal (NP) swab in UTM/UVT specimens obtained from symptomatic individuals suspected of COVID-19…
- Trial name
- NCT06360757
- Testing
- NeuMoDx SARS-CoV-2 Assay
- Where
- United Kingdom
- Volunteers
- 503 people
- Sponsor
- QIAGEN Gaithersburg, Inc
SARS-COV-2 Pneumonia
Long-term Evolution of Pulmonary Involvement of Novel SARS-COV-2 Infection (COVID-19): Follow the Covid Study
In December 2019 the first case of human infection by a new coronavirus was identified, currently called SARS-COV-2 (Severe Acute Respiratory Syndrome - Coronavirus - 2), characterized by high contagiousness and the possibility…
- Trial name
- NCT04605757
- Testing
- Clinical, functional and radiological lung involvement evolution
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Covid-19
Study of seroPREvalence Vis-à-vis SARS-CoV2 and Correlation With Clinical Forms of COVID-19 in Patients Followed in Pneumology in the Cluster Area of the Grand-Est Region (Strasbourg University Hospital)
seroPREvalence vis-à-vis SARS-CoV2 and correlation with clinical forms of COVID-19 in patients followed in Pulmonology in the cluster area of the Grand-Est region.
- Trial name
- PRESAGE (NCT04528901)
- Where
- France
- Volunteers
- 1,080 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19, SARS-CoV-2 Infection
A Study to Evaluate the Immunogenicity and Safety of A Recombinant Protein COVID-19 Vaccine as Booster Vaccines
This study is a phase Ⅱ clinical trial to evaluate the safety and immunogenicity of SCTV01E-2 in people of different ages who had been vaccinated with COVID-19 vaccines.
- Trial name
- NCT05933512
- Testing
- SCTV01E-2, SCTV01E
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Covid19
COVID-19 Immunologic Antiviral Therapy With Omalizumab
To evaluate if omalizumab is effective in decreasing mortality in severe hospitalized COVID-19 cases.
- Trial name
- CIAO (NCT04720612)
- Testing
- Omalizumab
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
SARS-CoV-2
Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial
This is a pragmatic randomized open-label study of the safety and efficacy of the combination of colchicine and Rosuvastatin in addition to standard of care (SOC) compared to SOC alone in hospitalized patients with SARS-CoV-2
- Trial name
- COLSTAT (NCT04472611)
- Testing
- Standard of Care (SOC) and Colchicine+Rosuvastatin
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Yale University
Covid19
Ultraviolet Germicidal Irradiation on the New Silicone Half-Piece Elastometric Respirators
Since the innovation of our new half- elastometric half-piece respirator, this type of FFR has been used widely in our country. Decontamination methods including ultraviolet C (UVC) germicidal irradiation and 70% alcohol have…
- Trial name
- NCT04749121
- Testing
- UVC Irradiation, Fit test, Tensile strength
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Post-acute COVID-19 Syndromes
The Roles of Vitamin D and Microbiome in Children With Post-acute COVID-19 Syndromes (PACS) and Long COVID
A double-blind study to evaluate the role of human microbiome and vitamin D in the development of long COVID and PACS in children.
- Trial name
- NCT05633472
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Healthy Participants
A Study to Learn About Two or More Vaccines That Are Put Together as One Shot Against Infectious Lung Illnesses, Including COVID-19 and Respiratory Syncytial Virus (RSV).
The purpose of the study is to learn about the safety and effects of a combined vaccine for RSV and COVID-19 when given with a seasonal flu vaccine or when given alone.
- Trial name
- NCT05886777
- Testing
- Combination [RSVpreF+BNTb162b2], Bivalent BNT162b2 (original/Omi BA.4/BA.5), RSVpreF
- Where
- 37 sites in United States
- Volunteers
- 1,142 people, healthy volunteers welcome
- Sponsor
- Pfizer
Coronavirus Infections
Coronavirus Disease 2019 (COVID-19) Study of Hospitalized Patients in Hong Kong
COVID-19 may cause another world-wide epidemic. This study is divided into 2 arms: (1) Prospective longitudinal observational study involving patients with laboratory-confirmed COVID-19 and (2) Retrospective study on patients…
- Trial name
- NCT04325919
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Chinese University of Hong Kong
Long COVID, Post Acute Sequelae of COVID-19
PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 have long-term symptoms that affect the brain.
- Trial name
- NCT06920628
- Testing
- 11C-PS13
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Vaccine Reaction
SARS-CoV-2 Antibodies and Virus Neutralisation in a Cohort Vaccinted Against COVID-19
Analysis of SARS-CoV-2 antibodies and serum virus neutralisation in vaccinated heath care personnel. Analysis of virus neutralisation as a function of age, gender, and history of COVID-19 infection.
- Trial name
- DER-CoV2-001 (NCT04979871)
- Testing
- Venous bleeding
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
SARS-CoV Infection
Do Angiotensin Receptor Blockers Mitigate Progression to Acute Respiratory Distress Syndrome With SARS-CoV-2 Infection
The purpose of this research is to identify whether or not Angiotensin Receptor Blockers (ARB) can halt the progression to respiratory failure requiring transfer into the intensive care unit (ICU), as well as halt mechanical…
- Trial name
- NCT04340557
- Testing
- Losartan
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Sharp HealthCare
SARS-COV2
Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients
The coronavirus disease (COVID-19) epidemic represents a major therapeutic challenge. The highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) and the long duration of the disease have led to a massive…
- Trial name
- NICOVID (NCT04608201)
- Testing
- Nicotine 7 mg/ 24h Transdermal Patch - 24 Hour
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Vagus Nerve Diseases, Long COVID
Vagus Stimulation in Female Long COVID Patients.
The aim of the present pilot study is to investigate the acceptance, feasibility and implementation of the vagus nerv stimulation in Long COVID patients.
- Conditions
- Vagus Nerve Diseases, Long COVID, Long Covid19, Post-COVID-19 Syndrome
- Trial name
- Vagus (NCT05918965)
- Testing
- transcutaneous electrical vagal neurostimulation
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
X-linked Agammaglobulinemia, XLA
COVID-19 Vaccine Responses in PIDD Subjects
The goal of our study is to assess the cellular immune responses of participants with antibody deficiency disease before and after immunization with SARS-CoV-2 mRNA vaccines.
- Conditions
- X-linked Agammaglobulinemia, XLA, Primary Immune Deficiency, CVID
- Trial name
- NCT05321407
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Duke University
COVID-19
Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal
COVID-19 is an emerging pandemic disease affecting most countries including Senegal, caused by the new coronavirus (SARS-CoV-2) which was first detected in the city of Wuhan in China in December 2019.
- Trial name
- SEN-CoV-Fadj (NCT04390594)
- Testing
- Nafamostat Mesilate
- Where
- 3 sites in Senegal
- Volunteers
- 59 people
- Sponsor
- Institut Pasteur de Dakar
Post-COVID Condition
Nutritional Intervention and Rehabilitation Treatment in Patients With Post-COVID Condition
SARS-CoV-2 is the coronavirus responsible for developing the disease known as COVID-19. Once the acute phase of the disease has passed, about 40% of the people who discharged continue to have symptoms, and of these, between 50…
- Trial name
- ARACOV-02 (NCT06063031)
- Testing
- Active
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
COVID-19
Safety and Immunogenicity of EXG-5003
This is a First in Human, randomized, placebo-controlled Phase I/II trial to evaluate the safety and immunogenicity of the intradermal COVID-19 vaccine, EXG-5003 in healthy adults.
- Trial name
- NCT04863131
- Testing
- EXG-5003
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fujita Health University
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