Clinical trials: SARS-COV2 Virus
COVID-19
Immune Responses to COVID-19 Infection or Vaccination
The overall purpose of this observational cohort study is to characterize COVID-specific immune responses to SARS-CoV-2 exposure or COVID vaccination in a real-world setting.
- Trial name
- NCT05379478
- Testing
- Laboratory assessment of antibody profiles
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- Aditxt, Inc.
Coronavirus Infections, Pneumonia, Viral
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 Brasil II)
The Severe Acute Respiratory Syndrome COronaVirus 2 (SARS-CoV2) is a new and recognized infectious disease of the respiratory tract.
- Trial name
- NCT04321278
- Testing
- Hydroxychloroquine + azithromycin, Hydroxychloroquine
- Where
- 58 sites in Brazil
- Volunteers
- 440 people
- Sponsor
- Hospital Israelita Albert Einstein
Coronavirus Disease 2019
Clinical Study on the Immune Program of Recombinant Novel Coronavirus（COVID-19) Vaccine (CHO Cell)
Popular topic：Clinical study on the immune program of recombinant Novel Coronavirus (COVID-19) vaccine (CHO cell). Research purpose:Main purpose: To evaluate the immunogenicity of recombinant novel coronavirus vaccine (CHO cells)…
- Trial name
- NCT05128643
- Testing
- Recombinant novel coronavirus vaccine (CHO cell)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Covid19
The Role of CT Chest Scan in the Pre-anesthetic Assessment of Suspected or Confirmed COVID -19 Patients
The role of CT scan of the chest in Pre-anesthetic assessment of the severity of COVID-19 and the correlations between CT measurements of the aortic and pulmonary arteries diameters and severity of pneumonia.
- Trial name
- NCT04560530
- Testing
- Non-enhanced CT scan of the chest
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Tanta University
SARS-CoV-2, SARS-CoV-2 (COVID-19) Infection
Study SARS-CoV-2-CZ-PREVAL-II - Arm of the Olomouc Region
The aim of the study is to find the proportion of people in the population of the Olomouc Region with the presence of IgG (or IgM) antibodies against the S and N antigens of the SARS-CoV-2 virus, therefore people who have already…
- Trial name
- NCT07387211
- Testing
- Blood sampling, Gargle sampling, Questionnaire completion
- Where
- Czechia
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Long COVID, Long COVID-19 Syndrome
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective.
- Conditions
- Long COVID, Long COVID-19 Syndrome, Long Covid19, Long Covid 19
- Trial name
- QoL COVID HBOT (NCT06159309)
- Testing
- Hyperbaric oxygen therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Rutger Lalieu
COVID-19, Convalescent Plasma Treatment
Convalescent Plasma Transfusion in Severe COVID-19 Patients in Jamaica
Corona virus Disease 2019 (COVID-19) can be a severe respiratory illness caused by Severe Acute Respiratory Syndrome (SARS-CoV2) for which there is no standard treatment in affected persons nor a vaccine to prevent the infection.
- Trial name
- NCT04644198
- Testing
- Convalescent Plasma Infusion
- Where
- Jamaica
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Covid19
SERUR: COVID-19 Serological Survey of Staff From the University Reims-Champagne Ardennes
This study was designed to determine, in a screening situation within the framework of university preventive medicine, the prevalence of positive anti-SARS-Cov 2 serology among the staff of the University of Reims…
- Trial name
- SERUR (NCT04816084)
- Testing
- Anti-SARS-CoV2 Serology
- Where
- France
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Corona Virus Infection, Coronavirus
imPulse™ Una Full-spectrum, Over Clothing E-stethoscope
This study generates robust clinical data to train ML/AI algorithms of the Sponsor's imPulse™ Una full-spectrum e-stethoscope for digital diagnostic feature synthesis of symptomatic SARS-CoV-2/COVID-19 biosignatures for rapid and…
- Trial name
- NCT04556149
- Testing
- imPulse™ Una e-stethoscope, Philips Lumify Ultrasound System
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Level 42 AI, Inc.
COVID-19
SA55 Novel Coronavirus Broad-spectrum Neutralizing Antibody Nasal Spray in Health People
To evaluate the safety, tolerance, local drug content and neutralization activity in nasal cavity, systemic exposure level and immunogenicity of novel coronavirus broad-spectrum neutralizing antibody SA55 nasal spray.
- Trial name
- NCT06048393
- Testing
- SA55 nasal spray
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Congenital Heart Disease, Covid-19
Impact of Covid-19 in Congenital Heart Disease
The ongoing Coronavirus (Covid-19) pandemic has recently generated the first epidemiological data on populations at risk. Currently, the risk factors, recognized for severe forms of Covid-19 infection, are elderly patients (> 70…
- Trial name
- COVID-CHD (NCT04336384)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
SARS-CoV-2 (COVID-19)
Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron Subvariants
COVHIC003 is a human infection challenge study in which healthy adults aged 18-50 previously vaccinated with an approved COVID-19 vaccine will be administered a SARS-CoV-2 Omicron EG.5.1 variant given by drops in the nose.
- Trial name
- COVHIC003 (NCT07397455)
- Testing
- SARS-CoV-2 Omicron EG.5.1 challenge agent 10^5 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^6 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^4 TCID50
- Where
- 5 sites in United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Coronavirus Disease 2019
COVID-19 Associated Lymphopenia Pathogenesis Study in Blood
Background: COVID-19 is an acute respiratory syndrome. One symptom of COVID-19 is a reduction in the number of cells called lymphocytes in the blood. Lymphocytes are a type of white blood cell that fights infections.
- Trial name
- NCT04401436
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Old Age; Debility, Vaccine Hesitancy
COVID-19 Vaccination Willingness in Older Adults Based on Self-determination Theory
Introduction: The COVID-19 vaccine is an effective measure for preventing and controlling COVID-19 epidemics, and the World Health Organization lists older adults as a high-priority group for COVID-19 vaccination.
- Conditions
- Old Age; Debility, Vaccine Hesitancy, Vaccine Refusal
- Trial name
- CVWIOABOSDT (NCT06575114)
- Testing
- Self-determination theory-based health education measures
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Jing-Shan Deng
Covid19
Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly
Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of…
- Trial name
- CORE (NCT04771052)
- Testing
- COVID Rehabilitation Program for the Elderly (CORE)
- Where
- 2 sites in Canada
- Volunteers
- 124 people
- Sponsor
- Université de Sherbrooke
SARS-CoV2 Infection
Rural Tailored COVID-19 Communication to Promote SARS-CoV-2 Antibody Testing in Saliva
This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among individuals residing in rural Northern Michigan.
- Trial name
- NCT06085547
- Testing
- General SARS-CoV-2 Communication, Rural-Targeted SARS-CoV-2 Communication
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Corona Virus Infection, COVID-19
Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial)
The purpose of this open label, randomized, study is to obtain information on the safety and efficacy of 80 ppm Nitric Oxide given in addition to the standard of care of patients with COVID-19 caused by SARS-CoV-2.
- Conditions
- Corona Virus Infection, COVID-19, SARS-CoV 2, Nitric Oxide
- Trial name
- NCT04397692
- Testing
- Nitric Oxide delivered via LungFit™ system
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Beyond Air Inc.
SARS-CoV-2 Infection
A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 Vaccine
The purpose of this study is to assess SARS CoV-2 infection, viral shedding, and subsequent potential transmission in individuals immunized with the Moderna COVID-19 vaccine.
- Trial name
- CoVPN 3006 (NCT04811664)
- Testing
- Moderna COVID-19 Vaccine
- Where
- 51 sites in United States
- Volunteers
- 1,923 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tracheal Stenosis
Observational Study for the Evaluation of Tracheal Stenosis in COVID-19 Patients
Define the actual incidence of tracheal stenosis in patients who underwent either prolonged intubation or tracheostomy and to compare incidence, clinical course and outcome between COVID-19 and non-COVID-19 patients.
- Trial name
- TS1 (NCT04686721)
- Testing
- Chest CT scan + baseline spirometry
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Clinico Humanitas
Sars-CoV2, Infection Viral
HCQ for Primary Prophylaxis Against COVID19 in Health-care Workers
Background: Aim: To demonstrate the efficacy of low-dose hydroxychloroquine as primary prevention in healthcare workers Design, participants and interventions: Prospective, randomized, parallel group, double-blinded, placebo…
- Conditions
- Sars-CoV2, Infection Viral, Healthcare Worker, Prophylaxis
- Trial name
- NCT04336748
- Testing
- Hydroxychloroquine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
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