Clinical trials: SARS-COV2 Virus
Diarrhea, COVID-19
Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol)
The Center for Disease Control (CDC) and World Health Organization (WHO) have deemed the COVID-19 virus a global pandemic of unprecedented severity in modern times.
- Trial name
- SABER-C (NCT04811339)
- Testing
- Bismuth Subsalicylate 262 milligram (mg) Oral Tablet, Chewable
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
SARS CoV 2 Infection, Vaccination; Infection
Monitoring COVID-19 Vaccination Response in Fragile Populations
The present study is part of ORCHESTRA project, a three-year international research project aimed at tackling the coronavirus pandemic.
- Conditions
- SARS CoV 2 Infection, Vaccination; Infection, Breakthrough Infection
- Trial name
- ORCHESTRA-4 (NCT05222139)
- Testing
- COVID-19 vaccination
- Where
- 20 sites in Argentina, Gabon and 5 more
- Volunteers
- 8,894 people
- Sponsor
- University of Bologna
Covid19
Early Detection of COVID-19 Using Breath Analysis - Feasibility Study
Early Detection of COVID-19 Using Breath Analysis -Feasibility Study.
- Trial name
- COVID-19 (NCT04602871)
- Testing
- Breath Biopsy
- Where
- 2 sites in Israel
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Scentech Medical Technologies Ltd
COVID-19
Evaluating the Response of the Immune System of People With Long COVID (Post SARS-CoV-2)
Many people who have had COVID 19 continue to experience symptoms long after they have recovered from the acute infection. This study will examine the clinical symptoms of people with "Long COVID" and measure various markers of…
- Trial name
- LCRC (NCT05131594)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Huntington Memorial Hospital
COVID-19 Infection
Long Covid (Individuals with Ongoing COVID-19 Symptoms) Ongoing Effects
Persistent Covid-19 symptoms, known as long Covid, can impact healthcare provision. This study aimed to assess how symptoms persisting six months after Covid-19 affect quality of life and functional capacity.
- Trial name
- COVID-19 (NCT06528145)
- Testing
- Evalation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ziya Yildiz
COVID 19
Inhaled Ciclesonide for Outpatients With COVID19
The CONTAIN (CiclesOnide cliNical TriAl covId-19 treatmeNt) is a randomized control study of ciclesonide vs placebo for mild covid-19 disease. The need for potential therapy for COVID-19 patients is urgent.
- Trial name
- CONTAIN (NCT04435795)
- Testing
- Ciclesonide, Ciclesonide nasal
- Where
- 3 sites in Canada
- Volunteers
- 215 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
SARS-CoV-2 Positive Patients
Follow-up Study of COVID-19 Patients in the District Konstanz
This is a prospective single-center study for the follow-up of SARS-CoV-2 positive patients in the district of Konstanz (LKN). As part of the coronavirus pandemic, patients with SARS-CoV-2 infection are currently being treated in…
- Trial name
- FSC19-KN (NCT04724434)
- Where
- Germany
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Hegau-Bodensee-Klinikum Singen
Lower Respiratory Tract Infection, Parainfluenza
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
This study will seek to enroll immunocompromised patients with Lower Tract parainfluenza infection. It also contains a sub-study to enroll patients with severe COVID-19.
- Conditions
- Lower Respiratory Tract Infection, Parainfluenza, Immunocompromised, COVID-19
- Trial name
- NCT03808922
- Testing
- DAS181, DAS181 COVID-19, DAS181 OL
- Where
- 28 sites in United States, Australia and 3 more
- Volunteers
- 274 people
- Sponsor
- Ansun Biopharma, Inc.
Covid 19
Allogenic UCMSCs as Adjuvant Therapy for Severe COVID-19 Patients
This study is conducted to assess the efficacy and safety of stem cells as adjunctive treatment for severe COVID-19 patients. Here, we want to study whether the administration of mesenchymal stem cells are safe and able to…
- Trial name
- UCMSC (NCT05132972)
- Testing
- Normoxic Allogenic UCMSC, Normal saline solution
- Where
- 3 sites in Indonesia
- Volunteers
- 42 people
- Sponsor
- Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
COVID-19, Sars-CoV2
Progesterone for the Treatment of COVID-19 in Hospitalized Men
The purpose of this study is to assess safety and efficacy of progesterone for treatment of COVID-19 in hospitalized men.
- Trial name
- NCT04365127
- Testing
- Progesterone 100 MG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sara Ghandehari
COVID-19
COVID-19: A POC Test Under Research & Evaluation
Collection of nasal/nasopharyngeal/throat swabs and blood samples from patients presenting at their designated care facility displaying symptoms of COVID-19 and undergoing a SOC SARS-CoV-2 test or those who have tested positive…
- Trial name
- CAPTURE (NCT04408066)
- Testing
- Sample Collection/Performance Evaluation (A), Sample Collection/Performance Evaluation (B)
- Where
- 3 sites in United Kingdom
- Volunteers
- 523 people
- Sponsor
- LumiraDx UK Limited
Respiratory Viral Infection, Respiratory Tract Diseases
PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT)
This is an open label controlled household-randomised trial designed to evaluate the efficacy of RESP301 alongside standard of care ("SOC") versus SOC alone.
- Conditions
- Respiratory Viral Infection, Respiratory Tract Diseases, COVID-19 Respiratory Infection
- Trial name
- PREVENT (NCT04842331)
- Testing
- RESP301 (a nitric oxide generating solution), Standard of Care (SOC)
- Where
- United Kingdom
- Sponsor
- Thirty Respiratory Limited
COVID-19
Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)
Phase III, single-center with co-participating units, randomized, double-blind, parallel, placebo-controlled clinical study
- Trial name
- NCT05033145
- Testing
- AZVUDINE
- Where
- 7 sites in Brazil
- Volunteers
- 312 people
- Sponsor
- HRH Pharmaceuticals Limited
COVID-19
The Efficacy, Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
This is a randomized, double-blinded, placebo controlled phase III clinical trial to evaluate the efficacy, safety and immunogenicity of SARS-CoV-2 Vaccine, Inactivated (Vero Cell) in adults aged 18 years and above after 2-dose…
- Trial name
- NCT04659239
- Testing
- Inactivated SARS-CoV-2 Vaccine (Vero cell)
- Where
- 2 sites in Brazil, Malaysia
- Volunteers
- 34,020 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Pneumonia, Viral, Covid19
Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19
Introduction: SARS-CoV2 infection produces severe pneumonia with pulmonary alveolar collapse. There is no specific treatment to date.
- Conditions
- Pneumonia, Viral, Covid19, ARDS, Oxidative Stress
- Trial name
- ANTIOX-COVID (NCT04570254)
- Testing
- Vitamin C, Vitamin E, Melatonin
- Where
- Mexico
- Volunteers
- 110 people
- Sponsor
- Unidad Temporal COVID-19 en Centro Citibanamex
Covid19
Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19.
The COMET-TAIL main study evaluated efficacy, safety, and tolerability of IM sotrovimab versus IV sotrovimab in high-risk patients for the treatment of mild/moderate COVID-19.
- Trial name
- NCT04913675
- Testing
- sotrovimab
- Where
- 50 sites in United States, France and 1 more
- Volunteers
- 1,065 people
- Sponsor
- Vir Biotechnology, Inc.
COVID, ARDS, Human
Compassionate Use Open-Label Anti-CD14 Treatment in Patients With SARS-CoV-2 (COVID-19)
This protocol proposes to use IC14, a recombinant chimeric monoclonal antibody (mAb) recognizing human CD14, to block CD14-mediated cellular activation in patients early in the development of ARDS.
- Conditions
- COVID, ARDS, Human, Ards, SARS-CoV2
- Trial name
- NCT04346277
- Testing
- IC14, a monoclonal antibody against CD14
- Where
- Italy
- Sponsor
- Implicit Bioscience
COVID
Double Therapy With IFN-beta 1b and Hydroxychloroquine
The novel coronavirus (SARS-CoV-2), is a single-stranded RNA coronavirus. The virus was first isolated from patients presented with pneumonia in Wuhan in December 2019.
- Trial name
- NCT04350281
- Testing
- Interferon Beta-1B, Hydroxychloroquine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Post-COVID / Long-COVID, POST-Covid 19
Effects of Hydrotherapy During Post-COVID-19 Rehabilitation
This randomized controlled study evaluates the effects of cold water hydrotherapy as an adjunct to standard rehabilitation in patients with Post-COVID Syndrome.
- Conditions
- Post-COVID / Long-COVID, POST-Covid 19, Post COVID Syndrome, Post-COVID Condition
- Trial name
- HydroCoVital A (NCT07013903)
- Testing
- Standard rehabilitation plus cold water hydrotherapy, Standard rehabilitation only
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Cardiorespiratory Fitness, Exercise
Tele-Rehabilitative Exercise Training Program in Nurses With Long COVID
Long COVID can cause a decline in cardiorespiratory fitness, resulting in fatigue and negative impacts on individuals' quality of life (QoL), particularly in nurses who play a crucial role in public health.
- Conditions
- Cardiorespiratory Fitness, Exercise, Long COVID, Nurses
- Trial name
- NCT06840873
- Testing
- wearable device, Healthy consulation
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Shang-Lin Chiang
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