Clinical trials: SARS-COV2 Virus
COVID-19 Pneumonia
A Different Use of The Aerosol Box in COVID-19 Patients; Internal Jugular Vein Cannulation
During the COVID-19 pandemic, health employees are at high risk of infection. This study aimed to determine experiences with an aerosol box (AB), used with the aim of preventing contamination by droplets during internal jugular…
- Trial name
- NCT04954118
- Testing
- Internal jugular vein cannulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
SARS-CoV Infection, Seroprevalence
Seroprevalence of SARS-CoV-2 in Unselected Surgical Patients: an Unicentric, Regional Study
The investigator analyzed the data of the patients admitted to the surgical department during the period 1St September - 10Th December 2020 to estimate the seroprevalence of SARS-CoV-2 infection in the setting of a non-dedicated…
- Conditions
- SARS-CoV Infection, Seroprevalence, Covid19
- Trial name
- COVID-19 (NCT04839913)
- Testing
- Antibodies testing
- Where
- Italy
- Volunteers
- 121 people
- Sponsor
- University of Cagliari
COVID 19 Vaccine
Third Dose of mRNA Vaccination to Boost COVID-19 Immunity (mBoost Study)
300 adults ≥30 years of age who have previously received two doses of an inactivated COVID-19 vaccine at least 3 months earlier will receive a third dose with an mRNA vaccine (BNT162b2, BioNTech).
- Trial name
- NCT05057182
- Testing
- BNT162b2
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
COVID-19 Pneumonia
Evaluation of the Efficacy and Safety of Nano-S1
This study aims to assess the efficacy of the efficacy and safety of investigational drug (NanoS) in patients with mild to moderate COVID-19 at high risk for progression to severe COVID-19, including death.
- Trial name
- COVNANOS1 (NCT05822180)
- Testing
- NANOS1 , argent colloïdal ,
- Where
- Tunisia
- Volunteers
- 116 people
- Sponsor
- General Administration of Military Health, Tunisia
Covid19
USEFULNESS of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19
Estimation of the prevalence and contagiousness of undocumented novel coronavirus infections is critical for understanding the overall prevalence and pandemic potential of this disease.
- Trial name
- IVERCAR (NCT04425850)
- Testing
- Iota carrageenan nasal spray and Ivermectin oral drops (used as buccal drops)
- Where
- Argentina
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Eurnekian Public Hospital
COVID-19
Pilot Clinical Trial to Explore Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients
This study is a multi-center, single-arm, open-label, pilot clinical trial to explore efficacy and safety of Pyramax in mild to moderate COVID-19 patients
- Trial name
- NCT05633420
- Testing
- Pyramax
- Where
- 2 sites in South Korea
- Volunteers
- 20 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
SARS-CoV-2, Ivermectin
The Zambia Ivermectin Trial for the Treatment and Prevention of COVID-19
The study aims to test whether Ivermectin would decrease mortality and reduces chances of getting infected with corona virus, improve management of clinical symptoms and reduce length of stay in ICU and transition probabilities…
- Trial name
- ZIT (NCT04891250)
- Testing
- Ivermectin, Prophylaxis
- Where
- Zambia
- Sponsor
- Centre for Infectious Disease Research in Zambia
Covid19
Combined Antihistaminics Therapy in COVID 19 Patients
The use of antihistaminic medications could result in a significant immune modulation which may help in the treatment of cytokine storm of COVID-19.Thus, the aim of this study is to evaluate efficacy and safety of famotidine and…
- Trial name
- NCT05043350
- Testing
- Loratadine, Famotidine
- Where
- Egypt
- Volunteers
- 214 people
- Sponsor
- Ain Shams University
Stress, Anxiety
Effects of Open-label Placebos on COVID-related Psychological Health
This project aimed to test the efficacy of a telehealth-administered placebo without deception intervention on stress, anxiety, and depression related to the COVID-19 pandemic.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT05035550
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Michigan State University
COVID 19
Colostrum From MERS-CoV Seropositive Camels for SARS-CoV-2 Infection - a Placebo-controlled Randomized Trial.
The study aims to study the efficacy of colostrum from MERS-CoV-positive camels applied as a nasal spray to COVID-19 patients for treatment and prevention of SARS-CoV-2 infection.
- Trial name
- NCT06857318
- Testing
- Colostrum Nasal Spray, Water for injection
- Where
- Israel
- Volunteers
- 43 people
- Sponsor
- Hadassah Medical Organization
COVID-19
A Phase II Clinical Trial to Evaluate the Recombinant Vaccine for COVID-19 (Adenovirus Vector)
This is a phase II, randomised, double-blinded and placebo-controlled clinical trial in healthy adults above 18 years of age. This clinical trial is designed to evaluate the immunogenicity and safety of Ad5-nCoV which encodes for…
- Trial name
- CTII-nCoV (NCT04341389)
- Testing
- Recombinant novel coronavirus vaccine (Adenovirus type 5 vector)
- Where
- China
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Institute of Biotechnology, Academy of Military Medical Sciences, PLA of China
Pregnancy, Covid19
Prevalence of COVID-19 (Coronavirus Disease 19) in Pregnant Women on Labor in a Public Hospital in Chile (COroNavirus diSease Covid-19 pandEmic iN ChilE)
This study aim is to assess the prevalence of SARS-COV-2 in unselected pregnant women on labour (or a predictable delivery during next 24 hours), their outcome and sociodemographic conditions.
- Conditions
- Pregnancy, Covid19, Labor (Obstetrics)--Complications, Demography
- Trial name
- CONSCIENCE (NCT04551690)
- Where
- Chile
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios, Santiago
SARS CoV 2 Infection
Inhibition of Bradykinin in COVID-19 Infection With Icatibant
There is excess accumulation of bradykinin during symptomatic SARS CoV-2 lung infection. Bradykinin causes oedema in the lung, with reduced oxygen. It also causes vasodilation, hypotension and cytokine release.
- Trial name
- ICASARS (NCT05407597)
- Testing
- Icatibant, 0.9% Sodium Chloride Injection
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Belfast Health and Social Care Trust
SARS-CoV-2 Infection, COVID19
Study to Evaluate Safety, Tolerability & Immunogenicity of BNT162b2 in Immunocompromised Participants ≥2 Years
This is a 4 dose study with 124 participants (7 adults ,117 children). Adults are considered to be participants 18 years of age or older. Participants are going to be enrolled based on conditions that make them immunocompromised.
- Trial name
- NCT04895982
- Testing
- BNT162b2
- Where
- 29 sites in United States, Brazil and 2 more
- Volunteers
- 124 people
- Sponsor
- BioNTech SE
COVID-19
IH Convidecia as Second Booster Dose Against Breakthrough Infections
This will be a randomized single-blind controlled trial to determine the immunogenicity, efficacy and safety of IH Convidecia (CanSino), as a second booster vaccination against Omicron and other emerging VOCs to prevent…
- Trial name
- NCT05517642
- Testing
- Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH), mRNA vaccine BNT162b2 (Pfizer)
- Where
- Malaysia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
COVID-19, Therapeutic Vaccine
COVID-19: BCG As Therapeutic Vaccine, Transmission Limitation, and Immunoglobulin Enhancement
To date, there is no vaccine or treatment with proven efficiency against COVID-19, and the transmissibility of the SARS-CoV-2 virus can be inferred by its identification in the oro-nasopharynx.
- Conditions
- COVID-19, Therapeutic Vaccine, BCG, SARS-CoV 2
- Trial name
- BATTLE (NCT04369794)
- Testing
- BCG
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- University of Campinas, Brazil
Covid19, Surgery--Complications
Impact of the COVID-19 Pandemic on the Surgical Activity of Bellvitge University Hospital
COVID-19 has been a challenge for hospitals; there was an obvious need to reconvert many spaces in specific areas to attend this pathology, without forgetting the attention to other pathologies and surgery.
- Conditions
- Covid19, Surgery--Complications, Nosocomial Infection
- Trial name
- NCT04780594
- Testing
- The study evaluates all surgical patients operated, both elective scheduled and emergent cases
- Where
- Spain
- Volunteers
- 2,530 people
- Sponsor
- Hospital Universitari de Bellvitge
COVID, Acute Respiratory Distress Syndrome
COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patients Affected With SARS-Cov-2
The first case of a person infected with SARS-Cov-2 virus can be tracked back on November the 17th, 2019, in China. On March 11, 2020, the World Health Organization (WHO) declared COVID-19 outbreak a pandemic.
- Conditions
- COVID, Acute Respiratory Distress Syndrome, Endothelial Dysfunction
- Trial name
- COVID-pO2-RAAS (NCT04524156)
- Testing
- Physiology
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm
SARS-CoV2
Methylene Blue Treatment of COVID-19
Despite enormous progress in understanding COVID-19, there is little evidence that a solution, therapeutic or preventive, is close to being achieved.
- Trial name
- NCT04635605
- Testing
- Methylene Blue, Control Test
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Fondazione Epatocentro Ticino
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