Clinical trials: SARS-CoV-2 Infection Covid19
Covid19, Cytokine Release Syndrome
Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan
Beyond supportive care, there are currently no proven treatment options for coronavirus disease (COVID-19) and related pneumonia, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).Investigators have seen…
- Conditions
- Covid19, Cytokine Release Syndrome, Critical Illness, ARDS
- Trial name
- NCT04492501
- Testing
- Therapeutic Plasma exchange, Convalescent Plasma, Tocilizumab
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- UNICEF
End Stage Renal Disease, Sars-CoV2
The Impact of COVID-19 on Dialysis Users
To understand the impact of COVID-19 restrictions on the wellbeing, quality of life and physical activity of people with end-stage renal disease, currently dialysing in-centre versus at home in the UK and their experience of…
- Trial name
- NCT04422873
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Covid19, Human Milk
The Effect of Covid-19 on Breast Milk Microbiome and Its Bioactive Components
Coronavirus disease (Covid-19) is a new public health crisis threatening humanity caused by SARS-CoV-2. Although it originated in China's Hubei province in late 2019, it has spread to many countries around the world.
- Trial name
- NCT04836754
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aysu Yıldız Karaahmet
COVID-19
CORonavirus (COVID-19) Diagnostic Lung UltraSound Study
This observational study is designed to assess whether focused lung ultrasound examination can improve the diagnosis of COVID-19 lung disease and/or make an alternative diagnosis at a patient's initial hospital presentation.
- Trial name
- COR-DLUS (NCT04351802)
- Testing
- Lung ultrasound
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University Hospital Plymouth NHS Trust
High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit
Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus
The novel Severe acute respiratory syndrome coronavirus 2 (SARS-C0V 2) originated in Wuhan, China in December 2019. As of April 15 2020, the virus has spread across 213 countries/territories with 1,914,916 cases and 123,010…
- Trial name
- NCT04403672
- Testing
- performance evaluation study of RealDetect RT-PCR Kit for COVID-19 detection
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Bangladesh Medical Research Council (BMRC)
Viral Respiratory Tract Infection
Safety and Tolerability of Single and Multiple Doses of Neumifil
This is a Phase 1, single-centre, randomised, placebo-controlled first in human study in healthy subjects. The study will assess the safety and tolerability of single-ascending (Part A) and multiple-ascending (Part B) doses of…
- Trial name
- NCT05093530
- Testing
- Neumifil
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pneumagen Ltd.
COVID-19
ECMO Braile Biomédica® in COVID-19 Patients
Retrospective data collection to evaluate the gas transfer capacity of the Braile Biomédica® OxyPrime® ECMO BRCoating® Membrane Oxygenator in COVID-19 patients during the pandemic.
- Trial name
- ECMO_COVID (NCT06086405)
- Testing
- Patients underwent cardiorespiratory support
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Covid19
Endoscopic Procedures of Children in the Normalization Process of Covid-19 Pandemic
Endoscopic methods are frequently used in the diagnosis of gastrointestinal system pathologies in children.
- Trial name
- NCT04598256
- Testing
- Endoscopic procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Tepecik Training and Research Hospital
Cancer
Booster Dose Trial
The goal of this study is to assess the safety and effectiveness of COVID vaccine booster doses in patients with cancer who have not developed an antibody after the U.S.
- Trial name
- NCT05016622
- Testing
- BNT162b2 vaccine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Montefiore Medical Center
COVID-19
Noncoding RNAs in COVID-19 and COVID-19 Related Kidney Dysfunction
In this study, critically ill patients with highly suspected or confirmed COVID-19 will be included. Main goal is the identification of noncoding RNAs in COVID-19 associated organ dysfunction with an emphasis on acute kidney…
- Trial name
- MiRCOVID (NCT04381351)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Chronic or Recovered Hepatitis B, Chronic or Recovered Hepatitis C
Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease
Background: The COVID-19 global pandemic killed more than 6 million people worldwide. Several vaccines have been developed against the virus that causes this disease.
- Conditions
- Chronic or Recovered Hepatitis B, Chronic or Recovered Hepatitis C, Chronic or Recovered Hepatitis D, NAFLD
- Trial name
- NCT05669677
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
COVID-19 Respiratory Infection
CRISPR/Cas9-modified Human T Cell ( PD-1and ACE2 Knockout Engineered T Cells ) for Inducing Long-term Immunity in COVID-19 Patients
T-cell exhaustion may limit long-term immunity in COVID-19 patients. T cells can lose their ability to fight viruses and tumors when they have prolonged exposure to these enemies.
- Trial name
- NCT04990557
- Testing
- PD-1 and ACE2 Knockout T Cells
- Volunteers
- 16 people
- Sponsor
- Mahmoud Ramadan mohamed Elkazzaz
SARS-CoV-2, COVID-19
eVusheld Assessment reaL wORld Effectiveness in the VA Health System
An AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and…
- Trial name
- VALOR-VA (NCT05663957)
- Testing
- Evusheld
- Where
- United States
- Volunteers
- 5,814 people
- Sponsor
- AstraZeneca
COVID-19
Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19
A pilot placebo-controlled randomized double-blind trial of Melatonin in outpatients with COVID-19 infection to evaluate Safety, Efficacy and Dose-ranging.
- Trial name
- NCT04784754
- Testing
- Melatonin
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Coronavirus Infection
Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant Therapy
This study will assess the prevalence and incidence of COVID-19 infection in patients with chronic plaque psoriasis on immunosuppressant therapy.
- Trial name
- NCT04324866
- Testing
- Nasopharyngeal swab
- Volunteers
- 300 people
- Sponsor
- Universita di Verona
Post Covid-19 Respiratory, Dyspnea
The Effects of a Music Therapy Respiratory Protocol on Post-Covid-19 Respiratory Symptoms
The effects of a tested and published music therapy respiratory protocol shown to be efficacious with pediatric asthma and adult COPD is being studied with individuals living with post-Covid-19 respiratory symptoms.
- Conditions
- Post Covid-19 Respiratory, Dyspnea, SARS-CoV 2
- Trial name
- NCT05231512
- Testing
- Respiratory Music Therapy Protocol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 1) - A Nationwide Multicentre Cross-Sectional Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04390165
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 498 people
- Sponsor
- Hospital Sultanah Bahiyah
Covid19
COVID-19 Infection in Cancer Pantients
It's an obsevational retrospective/prospective study. Analyzing the evolution of COVID 19 infection in cancer patients can provide interesting information in the management of these patients.
- Trial name
- COICA (NCT04569292)
- Testing
- No intervention on patients
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Ospedale Andrea Tortora di Pagani
Viral Pneumonia, Sepsis
Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis
This prospective observational pilot study investigates circulatory coherence in patients with COVID and non-COVID sepsis by comparison of microcirculation, endothelial glycocalyx, and clinical course
- Trial name
- NCT04644302
- Testing
- microcirculation recording
- Where
- Czechia
- Volunteers
- 28 people
- Sponsor
- University Hospital Hradec Kralove
COVID-19
Clinical Trial of Efficacy and Safety of Sinovac's Adsorbed COVID-19 (Inactivated) Vaccine in Healthcare Professionals
This is a phase III clinical trial to assess efficacy and safety of the Adsorbed COVID-19 (inactivated) vaccine manufactured by Sinovac in health care professionals
- Trial name
- PROFISCOV (NCT04456595)
- Testing
- Adsorbed COVID-19 (inactivated) Vaccine
- Where
- 16 sites in Brazil
- Volunteers
- 12,688 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.