Clinical trials: SARS-CoV-2 Infection Covid19
MS (Multiple Sclerosis), COVID-19
SUNLIGHT Study: Online Support Groups for MS to Address COVID-19
Stress and anxiety can have an adverse impact on health, and the experience of many around the 2020 outbreak of COVID-19 is affecting health and well-being.
- Conditions
- MS (Multiple Sclerosis), COVID-19, Support Groups
- Trial name
- NCT04379661
- Testing
- Online support Group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
COVID-19
Trial of 2nd Booster Dose of COVID-19 Vaccine
Background Recent studies indicate that a 2nd booster dose is associated with lower risk of severe COVID-19. The studies are based on Israeli registry data, comparing outcomes among individuals who have taken the booster, or not.
- Trial name
- NCT05539703
- Testing
- Invitation to get a 2nd booster dose of COVID-19 vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
COVID-19
Safety and Efficacy of Softgel KOVIR (TD0068) in the Combination Regimen With Background Treatment in COVID-19 Patients (KOVIR)
The acute pneumonia pandemic caused by a new strain of corona virus 2019 named as COVID-19 by the World Health Organization (WHO) is a pandemic caused by SARS-CoV-2 virus.
- Trial name
- NCT05082727
- Testing
- KOVIR (TD0068) oral softgel
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Sao Thai Duong Joint Stock Company
Acute Respiratory Distress
The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19
This is a phase II study to test adenosine efficacy for down-regulation of the overwhelming inflammation of COVID-19 in the lungs as reflected by clinical recovery of lung function; resolution of clinically relevant markers of…
- Trial name
- NCT04588441
- Testing
- Adenosine
- Sponsor
- University of Florida
COVID-19 Pneumonia
Real-world Evidence of COVID-19 Vaccines Effectiveness
This is an observational case-control study to evaluate COVID-19 vaccine effectiveness against hospitalisation with COVID-19 related conditions in St. Petersburg, Russia.
- Trial name
- NCT04981405
- Testing
- COVID-19 Vaccines
- Where
- 2 sites in Russia
- Volunteers
- 182 people
- Sponsor
- Ivan S Moiseev
COVID-19
Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults
This Phase III study will assess whether AZD7442 (a combination of 2 mAbs) can safely treat outpatient adults with COVID-19 and prevent either severe COVID-19 or death.
- Trial name
- TACKLE (NCT04723394)
- Testing
- AZD7442
- Where
- 103 sites in United States, Argentina and 13 more
- Volunteers
- 910 people
- Sponsor
- AstraZeneca
Covid-19
Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.
The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.
- Trial name
- NCT06259656
- Testing
- COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vachira Phuket Hospital
Severe Acute Respiratory Syndrome Coronavirus 2
An Exploratory Study of ADR-001 in Patients with Severe Pneumonia Caused by SARS-CoV-2 Infection
Safety and efficacy of ADR-001 are evaluated in Patients with Severe Pneumonia caused by SARS-CoV-2 infection.
- Trial name
- COVID-19 (NCT04522986)
- Testing
- Mesenchymal stem cell
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Rohto Pharmaceutical Co., Ltd.
SARS-CoV-2, Covid19
National Survey Concerning Vaccination Against COVID-19 in Nursing Homes and Long-Term Care Units
The COVID-19 pandemic is a challenge for the French healthcare system, particularly among the elderly due to their particular vulnerability to the serious consequences of the disease, with an estimated mortality rate of around…
- Trial name
- VACOVID-SENIOR (NCT04779541)
- Testing
- observation
- Where
- France
- Volunteers
- 323 people
- Sponsor
- University Hospital, Angers
SARS-CoV Infection
Efficacy of L. Plantarum and P. Acidilactici in Adults With SARS-CoV-2 and COVID-19
Clinical research focused to evaluate the effect as coadyuvant of a combination of L. plantarum and P. acidilactici in adults positive for SARS-CoV-2 with mild clinical COVID-19 symptoms.
- Trial name
- NCT04517422
- Testing
- Probiotics
- Where
- Mexico
- Volunteers
- 300 people
- Sponsor
- AB Biotics, SA
COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19 The purpose of this Interventional study is to investigate the effect of high frequency chest wall oscillation in hospitalized COVID-19…
- Trial name
- HFCWO IN COVID (NCT05705661)
- Testing
- HIGH FREQUENCY CHEST WALL OSCILLATION
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Covid-19 Infection
Awake Pronation for Covid-19 Treatment
Observational studies have shown that prone position (PP) in spontaneously breathing patients, may improve oxygenation in individuals with Acute Respiratory Failure (ARF), due to Covid-19 infection.
- Trial name
- NCT04667286
- Testing
- Prone Position (PP)
- Where
- 3 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Coronavirus, Pneumonia
Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)
There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers.
- Conditions
- Coronavirus, Pneumonia, Oxygen Toxicity
- Trial name
- NCT04320056
- Testing
- Standard administration of oxygen flow, Automated oxygen administration - FreeO2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Laval University
Vaccine Hesitancy
Motivational Interviewing for Vaccine Uptake in Latinx Adults
The goal of this clinical trial is to test whether modified behavioral health services, integrating motivational interviewing, will reduce vaccine hesitancy and increase uptake for the COVID-19 and influenza vaccines among Latinx…
- Trial name
- MIVacuna (NCT06062056)
- Testing
- EHR alert, Motivational Interviewing, Warm hand off to nurse
- Where
- 2 sites in United States
- Volunteers
- 3,698 people, healthy volunteers welcome
- Sponsor
- Boston College
Covid19, Post-COVID / Long-COVID
Post-coronavirus Disease-2019 Fatigue
Background: COVID-19 is consistently spreading throughout the world, and the number of recovered patients is steadily increasing.
- Trial name
- NCT04851561
- Testing
- Cardiopulmonary stress test (CPET)
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Covid19
Phase 1 Study to Assess Safety, Tolerability, PD, PK, Immunogenicity of IV NTR-441 Solution in Healthy Volunteers and COVID-19 Patients
This first-in-human clinical study is a Phase 1a/ 1b, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, and PK/PD of NTR-441 in healthy subjects and patients with COVID-19 after single…
- Trial name
- NCT04941183
- Testing
- NTR-441
- Where
- 4 sites in Austria, Ukraine
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Neutrolis
COVID-19
Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System
In the current COVID-19 pandemic with coronavirus, SARS-COV2, the Danish Health Authorities recommend using facial masks in the health care system when handling patients presumed or proven to be infected with the virus.
- Trial name
- NCT04337541
- Testing
- Surgical facial mask
- Where
- Denmark
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Covid19
Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection
The COVID-19 infection primarily manifests itself as a respiratory tract infection, although new evidence indicates that this disease has systemic involvement involving multiple systems including the cardiovascular, respiratory…
- Trial name
- HEPMAB (NCT04600141)
- Testing
- Tocilizumab, Heparin - Therapeutic dosage, Heparin - Prophylactic dosage
- Where
- 3 sites in Brazil
- Volunteers
- 308 people
- Sponsor
- University of Sao Paulo
SARS-CoV-2 (Covid19)
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects
This study will assess the safety and efficacy of TSC as a treatment for participants who are infected with SARS-CoV-2 (COVID-19).
- Trial name
- NCT04573322
- Testing
- Trans Sodium Crocetinate, Normal saline
- Where
- Romania
- Volunteers
- 25 people
- Sponsor
- Diffusion Pharmaceuticals Inc
Consent
Surgical Consent During the COVID-19 Pandemic
Multiloop audit of consenting practice in surgical procedures during the COVID-19 pandemic
- Trial name
- NCT04556604
- Testing
- Educational meetings and visual prompts
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medway Primary Care Trust
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