Clinical trials: SARS-CoV-2 Infection Covid19
SARS-CoV-2 Infection, COVID-19
An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Following an infection with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV2), one in ten people will experience persisting symptoms, or develop symptoms which can last for months and even years.
- Trial name
- ERASE-LC (NCT05911906)
- Testing
- Remdesivir
- Where
- 4 sites in United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Derby
Thrombosis, Covid-19
Thrombosis and Covid-19
The coronavirus disease of 2019 (COVID-19) is a viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), now deemed a pandemic by the World Health Organization.
- Conditions
- Thrombosis, Covid-19, SARS-CoV 2
- Trial name
- COVBIO (NCT04366778)
- Testing
- TEM-tPA
- Where
- France
- Volunteers
- 341 people
- Sponsor
- Hospices Civils de Lyon
COVID-19, INTERFERON
Treatment of COVID-19 by Nebulization of Inteferon Beta 1b Efficiency and Safety Study
COVID-19 is causing a serious viral pandemic in terms of health and social impact. To date, no treatment has yet demonstrated Strong efficacy in treating the infectious disease (COVID-19).
- Conditions
- COVID-19, INTERFERON, NEBULIZATION
- Trial name
- COV-NI (NCT04469491)
- Testing
- inhaled type I interferon, WFI water nebulization
- Where
- 7 sites in France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
COVID-19 Acute Respiratory Distress Syndrome
Positive End Espiratory Pressure Trial in Coronavirus Disease 19 Treated With Continuous Positive Airway Pressure
Consecutive patients with hypoxemic respiratory failure, CT evidence of bilateral pneumonia and diagnosis of Coronavirus Disease 19 (COVID-19) with molecular nasopharyngeal swab consecutively admitted to the COVID Care Unit of…
- Trial name
- NCT05178160
- Testing
- PEEP Standard Protocol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Santa Maria delle Grazie Hospital
Vaccine Hesitancy, COVID-19
The Impact of a Web-based Psychoeducation Programme with a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy
Vaccine hesitancy is defined as 'delay in acceptance or refusal of vaccines, despite the availability of vaccine service' and was named one of the top ten global health threats by the World Health Organization in 2019.
- Trial name
- NCT05531058
- Testing
- AI-driven Vaccine Communicator, Self-learning of COVID-19 vaccine knowledge
- Where
- Hong Kong
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Corona Virus Infection, Covid19
Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19
A preparation of CimertrA, comprising Artemisinin, Curcumin, and Boswellia, and Vitamin C in a nanoparticular formulation, is proposed as a treatment for the disease associated with the novel coronavirus SARS-CoV-2.
- Conditions
- Corona Virus Infection, Covid19, SARS-CoV Infection
- Trial name
- CimetrA (NCT04802382)
- Testing
- Confirm SARS-CoV-2 infection, Physical Examination, Vital Signs
- Where
- 2 sites in Israel
- Volunteers
- 252 people
- Sponsor
- MGC Pharmaceuticals d.o.o
COVID19 Pneumonia
Trial Evaluating Efficacy and Safety of Bevacizumab (Avastin®/Zeribev®) in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort
Bevacizumab, ZERIBEV® (Pfizer)/AVASTIN® (Roche) 25 mg/ml ®, is a recombinant humanised monoclonal IgG1 antibody It seems interesting to use bevacizumab in severe patients infected with SARS-CoV-2 requiring hospitalization in…
- Trial name
- CORIMMUNO-BEVA (NCT04344782)
- Testing
- Bevacizumab Injection
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Compass Course: COVID-19
A group of clinicians and researchers developed an 8-session group intervention that integrates education, support, self-reflection, and action-expectation to help people reaffirm or reconstruct self-grounded purpose after…
- Trial name
- CC-COVID (NCT05295238)
- Testing
- Compass Course
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Allina Health System
Sars-CoV2, Severe Neurologic Injury
COVID-19 Brain Injury
A prospective cohort minimal risk study to determine the impact of the COVID-19 crisis on outcomes of neurologically injured ICU patients.
- Conditions
- Sars-CoV2, Severe Neurologic Injury, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT04496076
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
COVID, Hypertension
Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19
Hospitalized patients with COVID-19 will be included in the study in centers around Poland. After the hospitalization, a short questionnaire will be completed, including pre-hospitalization diagnoses, pre-hospitalization…
- Conditions
- COVID, Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- COR-CARDIO (NCT04374110)
- Testing
- Clinical data
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Sars-CoV-2 Infection
AIDI - Research & Development of a Multisensor-Based Machine Learning Technology for Real-Time Automated Detection of COVID-19 Decompensation
The AIDI study has to phases. It's purpose is to capture vital signs using a non-invasive, hand-held, home monitoring device (MouthLab Device) from individuals with COVID-19 or who test positive for SARS-CoV-2 (Phase I) and use…
- Trial name
- AIDI (NCT05220306)
- Testing
- Monitoring of vital signs
- Where
- United States
- Sponsor
- AIDAR Health, Inc.
Physical Exercise, Disability Physical
Functional Training Improves the Functional Capacity and Physical Fitness of People Whit Spinal Cord Injury
The aim of this study is to understand the effect of adapted functional training on the physical fitness, functionality and quality of life of individuals with SCI after social distancing due to COVID-19.
- Trial name
- NCT06391658
- Testing
- Functional Training
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Covid19
Process Evaluation of a Residence-Based SARS-CoV-2 Testing Participation Pilot
Mixed-methods process evaluation of a residence-based asymptomatic SARS-CoV-2 testing participation pilot
- Trial name
- RB-TPP (NCT05045989)
- Testing
- Residence-based testing participation pilot (SARS-CoV-2 testing with relaxed social distancing restrictions)
- Where
- United Kingdom
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
COVID-19
A Study on Children With COVID-19 Admitted at Assiut University Children Hospital
The aim of study is to: 1-describe demographic and clinical data of children infected with COVID-19 admitted at isolation unit of Assiut university children hospital 2- assess the risk factors responsible for complications of…
- Trial name
- NCT05421247
- Volunteers
- 98 people
- Sponsor
- Assiut University
Diagnostic Test, Routine, Coronavirus
COVID-19 Testing Pilot Study
The purpose of this study is to determine the reliability of a low-cost rapid diagnostic test for COVID-19. The method of the testing procedure uses electrochemistry to detect COVID-19 spike proteins within human samples.
- Conditions
- Diagnostic Test, Routine, Coronavirus, Diagnoses Disease, Rapid Coronavirus Test
- Trial name
- NCT04843878
- Testing
- COVID Detect
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Severe Acute Respiratory Syndrome
Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tübingen Children
This is a prospective, longitudinal study to determine the incidence of SARS-COV-2 infection in children and adolescents by measuring specific antibodies in non-invasive saliva sampled in kindergartens and schools in a defined…
- Trial name
- Coro-Buddy (NCT04581889)
- Testing
- Diagnostic test
- Where
- Germany
- Volunteers
- 2,380 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
COVID-19
CAPTION AI to Minimize Risk of COVID Exposure
Participants scheduled for for an echocardiogram (echo) and being evaluated for, or is positive for COVID-19 will be asked if they would be willing to have their echo done using a new software program on one of the hand-held…
- Trial name
- CAPTION AI (NCT04336774)
- Testing
- Caption AI
- Where
- 2 sites in United States
- Sponsor
- Duke University
Cardiovascular Risk Factor, Burnout
Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu Dhabi
The main objective of our project is to investigate the evolution of psychosocial, cardiovascular and immune markers in healthcare with different levels of exposure to the COVID-19 pandemic.
- Conditions
- Cardiovascular Risk Factor, Burnout, Immune Deficiency
- Trial name
- NCT04422418
- Where
- 4 sites in United Arab Emirates
- Volunteers
- 200 people
- Sponsor
- Khalifa University for Science and Technology
COVID-19, Mental Health Impairment
A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization.
This study presents a digital mental-health protocol designed to offer remote, personalized support to former or current COVID-19 patients. A total of 100 subjects will be enrolled.
- Conditions
- COVID-19, Mental Health Impairment, Telemedicine
- Trial name
- DigiCOVID (NCT05231018)
- Testing
- Psychotherapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Covid19, SARS-CoV Infection
A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE
This study is randomized, double-blind (blinded for the trial subject and the study physician), placebo-controlled trial in the parallel assignment of the immunogenicity, and safety of the Gam-COVID-Vac combined vector vaccine…
- Trial name
- SPUTNIK-UAE (NCT04656613)
- Testing
- Gam-COVID-Vac
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
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