Clinical trials: SARS-CoV-2 Infection Covid19
Covid19, Coronavirus
Lung Ultrasound Findings in Patients With COVID-19 in a UK ED
The investigators aim to carry out a retrospective observational study, analysing lung ultrasound images from patients who have presented to A\&E for routine diagnostic purposes (ruling out cardiogenic pulmonary oedema, Pulmonary…
- Conditions
- Covid19, Coronavirus, Corona Virus Infection, SARS-CoV Infection
- Trial name
- NCT05065827
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
SARS-CoV-2 Infection, COVID-19
Effect of COVID-19 Lockdown on Alcohol and Tobacco Use in Two Chilean Universities
This is a longitudinal study of participants from two university communities in Chile. The primary objective is to examine the effect of a regional lockdown on alcohol and tobacco use, using a difference-in-difference analysis to…
- Trial name
- NCT05069090
- Testing
- Lockdown and other social distancing measures
- Where
- 2 sites in Chile
- Volunteers
- 1,038 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Covid19, Coronavirus
Lung Ultrasound Changes in Covid 19 Patients Discharged From Hospital
Lung ultrasound has been used to help diagnose COVID-19 as an alternative to CT scanning and chest X-ray. CT scanning is onerous and there are difficulties taking critically unwell patients there as well as decontamination…
- Conditions
- Covid19, Coronavirus, Coronavirus Infection, SARS-CoV Infection
- Trial name
- NCT05062603
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
SARS-CoV-2 Acute Respiratory Disease
Muscle Evaluation of Patients Infected by the Coronavirus
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents risk to develop muscle weakness associated with prolonged period of mechanical ventilation support and hospital stay.
- Trial name
- NCT05063214
- Testing
- Muscle ultrasound evaluation
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- Hospital Israelita Albert Einstein
SARS-CoV Infection, Covid19
COVID-19: SARS-CoV-2 Detection in Saliva, Oropharyngeal and Nasopharyngeal Specimens
The aim of this study is to compare the SARS-CoV-2 detection rate using either a Saliva, oropharyngeal swabs or nasopharyngeal swab method for specimen collection.
- Conditions
- SARS-CoV Infection, Covid19, Coronavirus
- Trial name
- NCT04715607
- Testing
- Sequence of testing.
- Where
- Denmark
- Volunteers
- 27,947 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
SARS-CoV Infection, Covid19
Study of HEarT DiseAse and ImmuNiTy After COVID-19 in Ireland
SETANTA study will investigate the incidence of cardiac abnormalities as assessed by cardiac magnetic resonance imaging in unselected patients after acute SARS-CoV-2 infection and correlation with immunological response and…
- Conditions
- SARS-CoV Infection, Covid19, Cardiomyopathies
- Trial name
- SETANTA (NCT04823182)
- Testing
- Cardiovascular Magnetic Resonance Imaging
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Institute Dublin
COVID-19, SARS-CoV-2
COVID-19 Pandemic Response Network
Coronavirus Disease 19 (COVID-19) represents an unprecedented challenge to the operations and population health management efforts of health care systems around the world.
- Conditions
- COVID-19, SARS-CoV-2, Coronavirus, Influenza -Like Illness
- Trial name
- NCT04320862
- Where
- United States
- Volunteers
- 9,207 people, healthy volunteers welcome
- Sponsor
- Duke University
SARS-CoV Infection, Anxiety
COVID-19-Related Health and Practices Among Dental Hygienists
As dental practices reopen their practices during a global pandemic, the risk of 2019 novel coronavirus (COVID-19) infection that dental hygienists face in providing dental care remains unknown.
- Conditions
- SARS-CoV Infection, Anxiety, Depression, Occupational Problems
- Trial name
- NCT04542915
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6,976 people, healthy volunteers welcome
- Sponsor
- American Dental Association
SARS-CoV Infection, Acute Respiratory Distress Syndrome
Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome
There are several clinical presentations of SARS-CoV-2 infection. Among the severe forms, pulmonary involvement with respiratory failure is common.
- Trial name
- COVIDEIT (NCT04603755)
- Testing
- Electrical Impedance tomography
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Covid19, SARS CoV 2 Infection
COVID-19: A Scope Research on Epidemiology and Clinical Course
Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) 2 infection and the associated coronavirus disease 2019 (COVID-19) are the most recent international health threat challenging our ability to protect populations, to…
- Conditions
- Covid19, SARS CoV 2 Infection, Sequelae of; Infection
- Trial name
- COVID-Scope (NCT05046769)
- Where
- Portugal
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
Coronavirus, SARS-CoV-2
Hemodynamic Characteristics of Patients With SARS-CoV-2
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a public health emergency of international concern.
- Conditions
- Coronavirus, SARS-CoV-2, COVID-19, Acute Respiratory Distress Syndrome
- Trial name
- PiCCOVID (NCT04337983)
- Testing
- Transpulmonary thermodilution, Echocardiography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Bicetre Hospital
SARS-CoV Infection, Acute Respiratory Distress Syndrome
Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19
A randomized, double blind, multicenter, placebo-controlled, parallel group, fixed dose, phase II study to evaluate the efficacy and safety of glenzocimab in ARDS.
- Conditions
- SARS-CoV Infection, Acute Respiratory Distress Syndrome, COVID-19, ARDS
- Trial name
- GARDEN (NCT04659109)
- Testing
- glenzocimab
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Acticor Biotech
SARS-CoV Infection, Interferon
The Containing Coronavirus Disease 19 (COVID-19) Trial
In recent months severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has emerged as a novel human pathogen and, susceptibility amongst humans is presumed to be universal.
- Conditions
- SARS-CoV Infection, Interferon, Covid19
- Trial name
- ConCorD-19 (NCT04552379)
- Testing
- Peginterferon beta-1a
- Where
- Chile
- Volunteers
- 1,173 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
SARS-CoV-2 Infection
PMMA vs Polysulfone in SARS-CoV-2 Infection Hemodialysis Patients
Controlled, prospective, open-label trial with a total duration of 2 weeks to assess the clearance of inflammatory interleukins by different membranes in haemodialysis patients with COVID-19.
- Trial name
- Dial-COVID (NCT05040737)
- Testing
- PS membrane versus PMMA membrane,
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
SARS-CoV-2 Infection, Safety and Efficacy
Plasma for Early Treatment in Non-hospitalised Mild or Moderate COVID-19 Patients
This is a prospective, randomized (1:1), double blind study of Convalescent anti-SARS-CoV-2 MBT Plasma (also known as convalescent plasma) plus standard medical treatment (SMT) versus placebo plus SMT in mild or moderate COVID-19…
- Trial name
- NCT04621123
- Testing
- Convalescent anti-SARS-CoV-2 MBT plasma, Control Group
- Where
- 4 sites in Spain
- Volunteers
- 384 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
SARS-COV-2 Infections, COVID-19
Fight COVID-19 Trial
A 6-Week Prospective, Open label, Randomized, in Multicenter Study of, Oseltamivir 300mg per day plus Hydroxychloroquine 800 mg per day versus Combination of Lopipinavir 800mg (or 10 mg/kg ) per day and Ritonavir 200 mg ( or 2.5…
- Trial name
- FIGHT-COVID-19 (NCT04303299)
- Testing
- Oral
- Where
- Thailand
- Volunteers
- 320 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
COVID-19, Corona Virus Infection
A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19
Agent Name and Study Duration ArtemiC is a medical spray comprised of Artemisinin (6 mg/ml), Curcumin (20 mg/ml), Frankincense (=Boswellia) (15 mg/ml) and vitamin C (60 mg/ml) in micellar formulation for spray administration.
- Conditions
- COVID-19, Corona Virus Infection, SARS-CoV 2, Coronavirus
- Trial name
- NCT04382040
- Testing
- ArtemiC
- Where
- 4 sites in India, Israel
- Volunteers
- 50 people
- Sponsor
- MGC Pharmaceuticals d.o.o
SARS-CoV Infection, Polymerase Chain Reaction
Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR
This is a study that will attempt to validate the process for detecting SARS-CoV-2 (COVID19) on a non-FDA-approved technology using self-collected saliva as the specimen.
- Conditions
- SARS-CoV Infection, Polymerase Chain Reaction, Laboratory Testing
- Trial name
- NCT04604145
- Testing
- SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
COVID-19, SARS-CoV-2 Infection
Investigation of Antibody and Immune Responses to SARS-CoV-2 Proteins in COVID-19 Patients
SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), has negatively impacted global health and requires more research to develop better tests and to improve disease treatment.
- Trial name
- SARS-CoV-2 (NCT04465981)
- Testing
- Sampling
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- INanoBio Inc.
COVID-19, SARS-CoV 2 Infection, Health Disparities
EMPOWER - BAME vs COVID
The COVID-19 virus pandemic has massively affected us all. Moreover, there is a disproportionately high number of COVID-19 severe infections and deaths in British Black, Asian and minority ethnic (BAME) patients.
- Trial name
- NCT04399733
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Future Genetics Limited