Clinical trials: SARS-CoV-2 Infection Covid19
COVID-19
Clinical Evaluation for Batch Consistency of Ad5-nCoV in Chinese Healthy Adults
This is a randomized, double-blind, parallel-controlled, equivalence trial, for evaluation of safety and immunogenicity, and batch-to-batch consistency of a recombinant adenovirus type-5-vectored Covid-19 vaccine Convidecia in…
- Trial name
- NCT05313646
- Testing
- batch 1 of Ad5-nCoV, batch 2 of Ad5-nCoV, batch 3 of Ad5-nCoV
- Where
- China
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
COVID-19
JINZHEN for Treatment of Mild to Moderate COVID-19
JINZHEN is a botanical drug that contains eight chemical constituents extracted from plant, mineral and animal origin raw materials.
- Trial name
- NCT05092503
- Testing
- JINZHEN Granules for Oral Solution
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Lianyungang Kanion Group, Ltd.
Sars-CoV2, Critical Illness
COVID-19 and ICU-acquired MDR Bacteria
This multicenter before-after study aimed to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired multidrug resistant (MDR) bacteria.
- Trial name
- COVID-BMR (NCT04378842)
- Where
- 7 sites in France
- Volunteers
- 368 people
- Sponsor
- University Hospital, Lille
Obesity, Telemedicine
Feasibility of a Telematics Pre-operative Assessment in a Bariatric Surgery During Covid-19
Coronavirus (COVID-19) is a respiratory disease caused by a newly discovered coronavirus, SARS-CoV-2. Several recent papers on the pandemic recognized obesity as a risk factor for the COVID-19 infection.
- Conditions
- Obesity, Telemedicine, Bariatric Surgery
- Trial name
- NCT04486417
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Sars-CoV-2 Infection, Long Covid19
Long Term Outcomes in COVID-19 Patients Recruited in the CORIST Project
Months after seemingly recovering from COVID-19, many patients continue to suffer from major long-term effects. Interestingly, the existence of direct link between the severity of the disease in its acute phase and the severity…
- Trial name
- CORIST-2 (NCT04907890)
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
COVID-19
Telerehabilitation in People With Long COVID
The aim of our study is to investigate the effectiveness of telerehabilitation in Post-COVID patients.
- Trial name
- NCT05205460
- Testing
- Home-based telerehabilitation, Education and self-exercise
- Where
- Taiwan
- Volunteers
- 182 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Perinatal Anxiety, Covid19
Augmented CBGT for Perinatal Anxiety During a Global Pandemic (COVID-19)
This study will evaluate the effectiveness of an augmented version of our current evidence-based Cognitive Behavioural Group Therapy (CBGT) for perinatal anxiety protocol with cognitive and behavioural strategies composed of…
- Trial name
- NCT04495803
- Testing
- Cognitive Behavioural Group Therapy for Perinatal Anxiety
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- St. Joseph's Healthcare Hamilton
SARS Pneumonia
Respiratory Mechanics and Gas Exchange in Patients With COVID-19 and Hypoxemic Acute Respiratory Failure
Data on respiratory mechanics and gas exchange in acute respiratory failure in COVID-19 patients is limited. Knowledge of respiratory mechanics and gas exchange in COVID-19 can lead to different selection of mechanical…
- Trial name
- COVID-VENT (NCT04445961)
- Testing
- Respiratory mechanics measurement, Gas exchange measurement
- Where
- 3 sites in Russia
- Volunteers
- 117 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Covid19, Pneumonia, Viral
Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection
This is a Randomized, Open-Label Study of the Efficacy and Safety of Aralast NP Infusion Therapy with Antiviral Treatment and standard of care versus Antiviral Treatment and standard of care (control group) in Hospitalized…
- Trial name
- NCT04675086
- Testing
- alpha1-proteinase inhibitor, Antiviral Agents
- Where
- United States
- Sponsor
- Blessing Corporate Services, Inc
Breast Cancer, Obesity
Implementation of a CDSS in Oncology Patients During COVID-19
The present randomised controlled trial aimed to investigate the effectiveness of a clinical decision support system (CDSS) in assisting clinicians to apply nutritional care to breast cancer (BC) patients during the COVID-19…
- Conditions
- Breast Cancer, Obesity, Cardiovascular Disease Other
- Trial name
- CDSS (NCT04876560)
- Testing
- Application of CDSS to provide nutritional care in breast cancer patients from home, General lifestyle advice to breast cancer patients by phone
- Where
- 2 sites in Greece
- Volunteers
- 44 people
- Sponsor
- Iaso Maternity Hospital, Athens, Greece
COVID-19
Lymphocyte to Procalcitonin Ratio in Covid-19 Patients
The lymphocyte/CRP ratio has been studied many times in covid-19 patients and has been proven to be an indicator of mortality as well as poor prognosis.
- Trial name
- NCT06620159
- Where
- Turkey (Türkiye)
- Volunteers
- 535 people
- Sponsor
- Suleyman Demirel University
COVID-19
Immunogenicity and Safety Study of the 3rd Booster Dose Using the High or Medium Dose of Inactivated (CoronaVac®) Vaccine in Healthy Adults in Turkey
This is a randomized, double-blinded, and positive-controlled Phase IIb clinical trial of COVID-19 vaccine (CoronaVac®) manufactured by Sinovac Research \& Development Co., Ltd.The purpose of this study is to evaluate the…
- Trial name
- NCT05150496
- Testing
- Medium-dose COVID-19 Vaccine(Vero Cell),Inactivated, High-dose COVID-19 Vaccine(Vero Cell),Inactivated
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
SARS-CoV-2
Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants
The study evaluated the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273.214 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in infants aged 12 weeks to < 6 months.
- Trial name
- BabyCOVE (NCT05584202)
- Testing
- mRNA-1273.214
- Where
- 39 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Covid19
Study to Evaluate the Effects of Tempol (MBM-02) in COVID-19 Patients.
An Adaptive, Randomized, Double-blind, Placebo-controlled study to examine the Effects of Tempol in subjects with COVID-19 infection.
- Trial name
- NCT04729595
- Testing
- Tempol
- Where
- 17 sites in United States
- Volunteers
- 248 people
- Sponsor
- Adamis Pharmaceuticals Corporation
Healthy, COVID-19
Building Resilience During the COVID-19 Pandemic: a Randomized Controlled Trial
This clinical trial is to test the efficacy of a Resilience Training (RASMUS) compared to an active control condition (Progressive Muscle Relaxation, PMR) on resilience, psychological distress, and other clinical variables in a…
- Conditions
- Healthy, COVID-19, Distress, Emotional
- Trial name
- NCT05802875
- Testing
- RASMUS Resilience Training, Progressive Muscle Relaxation
- Where
- Austria
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Patients With COVID-19
Conducting Clinical Trials of the Medicine "Rutan Tablets 0.1g" No. 10 in the Complex Therapy of COVID-19
The purpose of this clinical trial is to evaluate the efficacy and safety of the registered drug Rutan 0.1 against SARS-CoV-2 in patients with COVID-19.
- Trial name
- NCT05859919
- Testing
- The drug "Rutan 0.1"., Basic treatment
- Where
- Uzbekistan
- Volunteers
- 57 people
- Sponsor
- Research Institute of Virology, Ministry of Health of the Republic of Uzbekistan
Covid19, Ketogenic Dieting
Eucaloric Ketogenic Diet in COVID-19 Cytokine Storm Syndrome
Covid 19 pandemia is causing millions of deaths worldwide. To date, the evidence gathered suggests that the subgroup of patients who present the most serious clinical feature of COVID-19 could have a "cytokine storm syndrome"…
- Trial name
- ketocovidiet (NCT04492228)
- Testing
- Ketogenic diet
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ospedale Policlinico San Martino
Covid19
Impact of Colchicine and Low-dose Naltrexone on COVID-19
The purpose of this study is to explore the impact of two medications-colchicine and low-dose naltrexone (LDN)-relative to standard of care (SOC) on COVID-19 disease progression to severe/critical illness and/or intubation in…
- Trial name
- COLTREXONE (NCT04756128)
- Testing
- Colchicine 0.6 mg, Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- HealthPartners Institute
COVID-19 Pneumonia
Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia
The purpose of this study is to evaluate the safety, pharmacokinetic and pharmacodynamics of lanadelumab administered by intravenous (IV) infusion when added to standard-of-care (SoC) in adults hospitalized with COVID-19…
- Trial name
- NCT04460105
- Testing
- Lanadelumab
- Sponsor
- Shire
COVID 19, Pulmonary Disease
COVID-19 Search in Conjunctival Cells
The patients enrolled in this study will be all patients entering triage with suspicion of SARS-CoV2. Planned activities are required by the nasopharyngeal swab in parallel with the analysis of the conjunctival swab to identify…
- Trial name
- COVID-T (NCT04364594)
- Testing
- conjunctival swab
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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