Clinical trials: SARS-CoV-2 Infection Covid19
Coronavirus Disease 2019(COVID-19)
Safety, Tolerability and Pharmacokinetics of SCTA01, an Anti-SARS-CoV-2 Monoclonal Antibody, in Healthy Chinese Subjects
The purpose of this study is to evaluate the tolerability, safety, pharmacokinetics of SCTA01(anti-SARS-CoV-2 monoclonal antibody) in Healthy Chinese Subjects.
- Trial name
- NCT04483375
- Testing
- SCTA01
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Parent-Child Relations, Parental Stress
Effects of an ACT-based Psychological Treatment in Relatives of People With Intellectual Disabilities
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of parental stress in relatives of people with intellectual disabilities
- Trial name
- NCT05611554
- Testing
- ACT
- Where
- Spain
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
COVID-19 Infection
Clinical Characteristics and Prognostic Factors of Patients With COVID-19 (Coronavirus Disease 2019)
This is a multicenter, non-interventional, retrospective study using data captured in the EHRs (Electronic Health Records) of the participating hospital sites to determine factors that predict disease prognosis and outcomes in…
- Trial name
- NCT04569851
- Where
- 2 sites in Spain
- Volunteers
- 100,000 people
- Sponsor
- Savana Research
COVID-19
Immunogenicity and Safety Study of Monovalent Omicron XBB.1.5 Vaccine as a Booster in Adults
The purpose of this study is to assess the immunogenicity and safety of SCB-2023B monovalent Omicron XBB.1.5 vaccine compared to the prototype SCB-2019 vaccine in participants previously vaccinated with 3 doses of inactivated…
- Trial name
- NCT06567457
- Testing
- SCB-2023B vaccine, a monovalent Omicron XBB.1.5 recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19, SCB-2019 vaccine, a monovalent wu-hu1 SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19
- Volunteers
- healthy volunteers welcome
- Sponsor
- Clover Biopharmaceuticals AUS Pty
Long COVID-19 Syndrome, Post COVID Syndrome Long Covid
Inspiratory Muscle Pressure and Diaphragmatic Strength in Women With Long COVID-19: A Pressure Biofeedback-Guided Training Study
COVID-19 is an infectious disease that can cause long-term health problems even after the acute infection has resolved. Many people who have recovered from COVID-19 continue to experience breathing difficulties, fatigue, and…
- Conditions
- Long COVID-19 Syndrome, Post COVID Syndrome Long Covid, Post COVID-19 Syndrome
- Trial name
- NCT07397130
- Testing
- Pressure Biofeedback Unit
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- RSUP Persahabatan
Sars-CoV2
Evaluation of the Pharmacokinetics and Pharmacodynamics of Hydroxychloroquine in COVID-19 Intensive Care Unit Patients
To date, no treatment has demonstrated clinical efficacy on COVID 19. However, several therapeutic strategies are being considered and are being evaluated in numerous clinical trials.
- Trial name
- PREAVIS (NCT04522466)
- Testing
- Hydroxychloroquine (HCQ)
- Where
- 4 sites in France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Severe COVID-19 Pneumonia
A Study to Evaluate the Safety and Effect of STC3141 Continuous Infusion in Subjects With Severe Corona Virus Disease 2019（COVID-19）Pneumonia
The study is a Randomized, Open-Label, Multi-Centre, Phase 2a Study to Evaluate the Safety and Effect of STC3141 Continuous Infusion in Subjects with Severe Corona Virus Disease 2019（COVID-19）Pneumonia.
- Trial name
- NCT04880694
- Testing
- STC3141
- Where
- 4 sites in Belgium
- Volunteers
- 25 people
- Sponsor
- Grand Medical Pty Ltd.
Deep Venous Thrombosis
Deep Venous Thrombosis in Non-severe COVID-19 Patients Hospitalized for a Neurovascular Pathology
Severe SARS-CoV-2 infection, responsible of COVID-19, is accompanied by many venous thromboembolic events. Antithrombotic treatment is the cornerstone of management of many neurovascular diseases (NVDs) and the benefit-risk ratio…
- Trial name
- VT-Covid-19 (NCT04452422)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19, ARDS
Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome
This study is meant to assess the lung mechanics in SARS-CoV-2 induced acute respiratory failure. A precise characterisation of lung mechanics and heart-lung-interactions might allow a better understanding of SARS-CoV-2 induced…
- Trial name
- LungMechCoV-19 (NCT04597853)
- Testing
- Assessment of lung mechanics and heart-lung interactions
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Post-acute Sequelae SARS-CoV-2 Infection (PASC)
TDCS-potentiated Generalization of Cognitive Training in the Rehabilitation of Long COVID Symptoms
The overarching goals of this study are to employ cognitive testing to understand how transcranial direct current stimulation (tDCS), when used concurrently with cognitive training tasks, can affect cognitive impairment symptoms…
- Trial name
- NCT05589272
- Testing
- Active tDCS
- Where
- United States
- Sponsor
- University of Minnesota
Post COVID-19
Value of Montelukast as a Potential Treatment of Post COVID-19 Persistent Cough
As of September 2020, the COVID-19 pandemic has affected millions of people in 196 countries and left hundreds of thousands dead.
- Trial name
- NCT05447039
- Testing
- Montelukast Sodium Tablets
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Anosmia
Prevalence and Outcomes of Olfactory and Gustatory Dysfunctions in Patients With COVID-19
Prevalence and Outcomes of Olfactory and Gustatory Dysfunctions in Patients with COVID-19
- Trial name
- NCT04524754
- Where
- Egypt
- Volunteers
- 218 people
- Sponsor
- Ain Shams University
Asymptomatic COVID-19
Study of Oral High/Low-dose Cepharanthine Compared With Placebo in Non Hospitalized Adults With COVID-19
The purpose of this study is to evaluate the efficacy and safety of high/low-dose cepharanthine for the Treatment of COVID-19 in asymptomatic and non-pneumonia mild adult participants with COVID-19 who do not need to be in the…
- Trial name
- NCT05398705
- Testing
- Cepharanthine
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
COVID-19, H1N1 Influenza
Comparison of COVID-19 and H1N1 Influenza Pneumonia
To explore the different clinical and CT features distinguishing COVID-19 from H1N1 influenza pneumonia.
- Trial name
- NCT04933994
- Testing
- computed Tomography
- Volunteers
- 483 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
SARS-CoV-2 Infection, Influenza Viral Infections
Hypothesizing the Genesis of Infectious Diseases and Epidemics Through an Integrated Systems Biology Approach
In this study, the investigators aim to collect phenotypical and extensive unbiased multimodal biological data, at two different time points, and to integrate them using a systems biology approach.
- Trial name
- HYGIEIA (NCT05557539)
- Testing
- blood samples, urine samples and nasopharyngeal swabs
- Where
- Belgium
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
COVID-19
Effectiveness of the Oxford-AstraZeneca COVID-19 Vaccine as a 2nd Booster, the REFORCO-Brazil Study
This study will address specific questions concerning the additional protection of the AZ COVID-19 vaccine as a second booster dose in preventing severe COVID-19 outcomes (hospitalisation, ICU admission etc) and will provide data…
- Trial name
- REFORCO-B (NCT05697705)
- Testing
- ChAdOx1 nCOV-19 vaccine (Vaxzeria), BNT162b2 (Pfizer), Ad26.COV2.S (Janssen)
- Where
- Brazil
- Volunteers
- 188,814,085 people
- Sponsor
- AstraZeneca
COVID-19
Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines
This is an open-label Phase 3 study evaluating the immunogenicity and safety of Novavax vaccine(s) with Matrix-M™ adjuvant (ancestral strain NVX-CoV2373 and an alternative strain and/or multivalent Novavax vaccine) as booster…
- Trial name
- NCT05875701
- Testing
- NVX-CoV2373, SARS-CoV-2 rS antigen/Matrix-M Adjuvant
- Where
- 5 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Novavax
Respiratory Distress Syndrome, Adult
A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS
A Phase 1 study of agenT-797 to treat moderate to severe acute respiratory syndrome in Coronavirus disease 2019 (COVID-19) participants.
- Trial name
- NCT04582201
- Testing
- agenT-797
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- MiNK Therapeutics
Covid19, Acute Respiratory Distress Syndrome
Clinical Features of COVID-19 Patients
The data were retrospectively collected during the first and the second wave of epidemic in COVID-19 patients with Severe Acute Respiratory Syndrome Coronavirus 2, at the moment of intensive care unit admission and during the in…
- Conditions
- Covid19, Acute Respiratory Distress Syndrome, Ventilatory Failure
- Trial name
- NCT04815304
- Testing
- peripheral lymphocytes subsets
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- San Salvatore Hospital of L'Aquila
COVID-19
S Protein and COVID-19: a Monocentric Prospective Study
The aim of this study is to compare plasma S Protein levels to SARS-CoV-2 viral load in COVID positive patients.
- Trial name
- PROS-Covid (NCT05351385)
- Testing
- Hematolgy and Chemistry analysis, Real Time PCR, PROS assay COVID+
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Milano Bicocca
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