Clinical trials: SARS-CoV-2 Infection Covid19
Covid19, Kidney Diseases
RECOVAC Repeated Vaccination Study
Rationale: The humoral and cellular immune response after two mRNA vaccinations is severely attenuated in kidney transplant patients compared to controls, especially when their immunosuppressive regimen contains mycophenolate…
- Conditions
- Covid19, Kidney Diseases, Vaccine Response Impaired, SARS-CoV2 Infection
- Trial name
- NCT05030974
- Testing
- mRNA-1273, Ad26.COV2.S vaccine
- Where
- 4 sites in Netherlands
- Volunteers
- 336 people
- Sponsor
- University Medical Center Groningen
Mental Health Wellness 1
Evaluation of Staff COVID-19 Wellbeing Centres in a Healthcare Workplace: COVID-WELL Study
Evaluation of a workplace intervention to implement supported wellbeing centres in a healthcare workplace during and after the COVID-19 pandemic.
- Trial name
- COVID-WELL (NCT04410016)
- Testing
- Staff Wellbeing Centres
- Where
- United Kingdom
- Volunteers
- 819 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
AMD, ACEi's/ARB Prevent/Worsen Risk of COVID-19 Infection
Long-term Use of Drugs That Could Prevent the Risk of Serious COVID-19 Infections or Make it Worse
The COVID-19 emerging disease due to a novel coronavirus (SARS-CoV-2), started in Wuhan, China, last December, 2019. In the past three months, the virus has spread rapidly worldwide to reach the pandemic threshold.
- Trial name
- TRAPSAH (NCT04356417)
- Testing
- - Synthetic anti-malarial drugs
- Where
- France
- Volunteers
- 6,000,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, SARS-CoV 2
Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection
This is a prospective, double-blind, randomized, placebo-controlled study in two distinct cohorts to evaluate the efficacy and safety of hydroxychloroquine in the prevention of COVID-19 infection.
- Trial name
- NCT04372017
- Testing
- Hydroxychloroquine, Vitamin D
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sanford Health
SARS-CoV 2
SARS-CoV2 (COVID-19) Diagnosis in Human Saliva by MALDI-TOF MS Profiling
Since March 2020, SARS-CoV2 virus (nCoV19; COVID-19) is considered pandemic. Its high rate of spread and infection in the human population and the lack of effective and validated treatment have led the authorities of several…
- Trial name
- CoviDiagMS (NCT04460638)
- Testing
- Saliva collection, Clinical assessment
- Where
- France
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Covid19
A Pilot Study for the Collection Of Vocalized, Individual Digital Cough Sound Recordings to Screen for COVID-19
Decentralized clinical study designed to collect cough sounds and self-reported symptoms alongside a COVID-19 realtime quantitative polymerase chain reaction (rt-qPCR) test.
- Trial name
- COVID-Cough (NCT04864535)
- Testing
- Recordings of cough sounds from adults
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- ResApp Health Limited
Chronic Disease, Covid-19 Pandemic
Effect of Hand-Washing Training in Covid-19
This study was conducted in order to inform, the women with chronic disease in rural areas, about hand-washing and nutrition, and to evaluate the efficiency of the training program.
- Trial name
- NCT04957017
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Respiratory Infection Virus, Respiratory Failure
Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19
A randomized, double-Blind, placebo-controlled trial aimed to investigate the safety and efficacy of sivelestat on treating adult patients with COVID-19-related acute respiratory distress syndrome (ARDS)
- Trial name
- NCT05697016
- Testing
- Sivelestat Sodium for Injection
- Volunteers
- 238 people
- Sponsor
- Beijing Tiantan Hospital
Autoimmune Liver Disease, COVID-19
Study of Clinical Features of Patients With Autoimmune Liver Disease Complicated With Covid-19 and the Immune Mechanism Affecting Prognosis
With the decreasing virulence of omicrons strain, the current domestic epidemic prevention policy has been changed based on the health of the people and the development needs of the country.
- Trial name
- NCT06099626
- Testing
- Different types of disease
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
COVID-19, Cytokine Storm
Intercellular Adhesion Molecule-1 and TNF-α in Patients With COVID-19
This study aimed to assess the cytokine profile in COVID 19 patients and its relation with disease progression \& severity using COVID reporting and data system (CORADS) score.
- Trial name
- NCT05408325
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
COVID 19
Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia
Coronavirus-2019 disease (COVID-19) and community-acquired pneumonia are significant problems of modern medicine. Pneumonia is the most common severe complication of COVID-19.
- Trial name
- TARGET-VIP (NCT04522076)
- Where
- 2 sites in Russia
- Volunteers
- 1,130 people
- Sponsor
- National Research Center for Preventive Medicine
Mental Health Wellness 1
Jump Start Plus COVID-19 Support
The purpose of the study is to further develop and examine the Jump Start Plus COVID Support (JS+CS) program, which encourages improved psychosocial functioning by promoting resiliency in childcare centers.
- Trial name
- NCT05445518
- Testing
- Jump Start Plus COVID Support, Healthy Caregivers-Healthy Children (HC2)
- Where
- United States
- Volunteers
- 1,505 people, healthy volunteers welcome
- Sponsor
- University of Miami
COVID-19
Health Professional Exposure Assessment to Covid-19
Understanding the SARS-Cov2 epidemic is a major public health issue, both in the community and in the hospital sector. Because of their central position in the management of patients infected with COVID-19, hospital staff may be…
- Trial name
- SERODRON (NCT04429724)
- Testing
- Diagnostic test Covid-19
- Where
- 4 sites in France
- Volunteers
- 2,129 people, healthy volunteers welcome
- Sponsor
- Tourcoing Hospital
Covid19, Cancer
Prospective Determination of COVID-19 Infection Rate in a Chemotherapy Unit in Mexico.
Cancer patients are considered vulnerable to COVID-19 infection. During the pandemic, cancer patients may need to continue their regular treatment of chemotherapy and / or radiotherapy and therefore must visit a hospital unit.
- Conditions
- Covid19, Cancer, Tumor
- Trial name
- NCT04567979
- Where
- Mexico
- Volunteers
- 149 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Covid19, SARS-CoV-2 Infection
A Trial of GC4419 in Patients With Critical Illness Due to COVID-19
A Trial of GC4419 in Patients with Critical Illness due to COVID-19
- Trial name
- NCT04555096
- Testing
- GC4419
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Galera Therapeutics, Inc.
COVID-19
A Study to Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney Disease
The purpose of this study is to learn about the side effects (safety) of the study medicine PF-07321332 (nirmatrelvir)/ritonavir for the treatment of mild to moderate COVID-19 infection in adults with severe renal impairment.
- Trial name
- NCT05487040
- Testing
- PF-07321332 (nirmatrelvir)/ritonavir
- Where
- 52 sites in United States
- Volunteers
- 15 people
- Sponsor
- Pfizer
COVID-19 Respiratory Infection
Novel Rapid POC Diagnostics for COVID-19
This is a prospective, multicentre study in which the diagnostic accuracy of multiple Covid-19 Antigen rapid diagnostic tests will be assessed for COVID-19 case detection using prospectively collected nasal swabs and saliva…
- Trial name
- NCT05438589
- Where
- 2 sites in Georgia, South Africa
- Volunteers
- 1,283 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Telemedicine, Surgery, Plastic
3D Telemedicine During COVID-19: Non-clinical Validation
Telemedicine will be used as standard practice during the Covid Pandemic, in order to reduce clinician exposure to patients and potential high viral load, and reduce patient footfall in a hospital caring for Covid patients.
- Trial name
- NCT04444297
- Testing
- 3D Telemedicine, 2D Telemedicine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Pneumonia Due to COVID-19
Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19
The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to pneumonia with…
- Trial name
- NCT06522724
- Testing
- Education program, Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Rzeszow
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